KEGG   Trichechus manatus latirostris (Florida manatee): 101348250
Entry
101348250         CDS       T05135                                 
Name
(RefSeq) protein kinase C alpha type isoform X2
  KO
K02677  classical protein kinase C alpha type [EC:2.7.11.13]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01521  EGFR tyrosine kinase inhibitor resistance
tmu04010  MAPK signaling pathway
tmu04012  ErbB signaling pathway
tmu04014  Ras signaling pathway
tmu04015  Rap1 signaling pathway
tmu04020  Calcium signaling pathway
tmu04066  HIF-1 signaling pathway
tmu04070  Phosphatidylinositol signaling system
tmu04071  Sphingolipid signaling pathway
tmu04072  Phospholipase D signaling pathway
tmu04150  mTOR signaling pathway
tmu04151  PI3K-Akt signaling pathway
tmu04261  Adrenergic signaling in cardiomyocytes
tmu04270  Vascular smooth muscle contraction
tmu04310  Wnt signaling pathway
tmu04360  Axon guidance
tmu04370  VEGF signaling pathway
tmu04510  Focal adhesion
tmu04540  Gap junction
tmu04613  Neutrophil extracellular trap formation
tmu04650  Natural killer cell mediated cytotoxicity
tmu04664  Fc epsilon RI signaling pathway
tmu04666  Fc gamma R-mediated phagocytosis
tmu04670  Leukocyte transendothelial migration
tmu04713  Circadian entrainment
tmu04720  Long-term potentiation
tmu04723  Retrograde endocannabinoid signaling
tmu04724  Glutamatergic synapse
tmu04725  Cholinergic synapse
tmu04726  Serotonergic synapse
tmu04727  GABAergic synapse
tmu04728  Dopaminergic synapse
tmu04730  Long-term depression
tmu04750  Inflammatory mediator regulation of TRP channels
tmu04911  Insulin secretion
tmu04912  GnRH signaling pathway
tmu04916  Melanogenesis
tmu04918  Thyroid hormone synthesis
tmu04919  Thyroid hormone signaling pathway
tmu04921  Oxytocin signaling pathway
tmu04925  Aldosterone synthesis and secretion
tmu04926  Relaxin signaling pathway
tmu04928  Parathyroid hormone synthesis, secretion and action
tmu04929  GnRH secretion
tmu04933  AGE-RAGE signaling pathway in diabetic complications
tmu04935  Growth hormone synthesis, secretion and action
tmu04960  Aldosterone-regulated sodium reabsorption
tmu04961  Endocrine and other factor-regulated calcium reabsorption
tmu04970  Salivary secretion
tmu04971  Gastric acid secretion
tmu04972  Pancreatic secretion
tmu05017  Spinocerebellar ataxia
tmu05022  Pathways of neurodegeneration - multiple diseases
tmu05031  Amphetamine addiction
tmu05032  Morphine addiction
tmu05143  African trypanosomiasis
tmu05146  Amoebiasis
tmu05161  Hepatitis B
tmu05163  Human cytomegalovirus infection
tmu05164  Influenza A
tmu05170  Human immunodeficiency virus 1 infection
tmu05171  Coronavirus disease - COVID-19
tmu05200  Pathways in cancer
tmu05205  Proteoglycans in cancer
tmu05206  MicroRNAs in cancer
tmu05207  Chemical carcinogenesis - receptor activation
tmu05214  Glioma
tmu05223  Non-small cell lung cancer
tmu05225  Hepatocellular carcinoma
tmu05231  Choline metabolism in cancer
tmu05415  Diabetic cardiomyopathy
tmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101348250
   04012 ErbB signaling pathway
    101348250
   04014 Ras signaling pathway
    101348250
   04015 Rap1 signaling pathway
    101348250
   04310 Wnt signaling pathway
    101348250
   04370 VEGF signaling pathway
    101348250
   04066 HIF-1 signaling pathway
    101348250
   04020 Calcium signaling pathway
    101348250
   04070 Phosphatidylinositol signaling system
    101348250
   04072 Phospholipase D signaling pathway
    101348250
   04071 Sphingolipid signaling pathway
    101348250
   04151 PI3K-Akt signaling pathway
    101348250
   04150 mTOR signaling pathway
    101348250
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101348250
   04540 Gap junction
    101348250
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101348250
   04650 Natural killer cell mediated cytotoxicity
    101348250
   04664 Fc epsilon RI signaling pathway
    101348250
   04666 Fc gamma R-mediated phagocytosis
    101348250
   04670 Leukocyte transendothelial migration
    101348250
  09152 Endocrine system
   04911 Insulin secretion
    101348250
   04929 GnRH secretion
    101348250
   04912 GnRH signaling pathway
    101348250
   04921 Oxytocin signaling pathway
    101348250
   04926 Relaxin signaling pathway
    101348250
   04935 Growth hormone synthesis, secretion and action
    101348250
   04918 Thyroid hormone synthesis
    101348250
   04919 Thyroid hormone signaling pathway
    101348250
   04928 Parathyroid hormone synthesis, secretion and action
    101348250
   04916 Melanogenesis
    101348250
   04925 Aldosterone synthesis and secretion
    101348250
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101348250
   04270 Vascular smooth muscle contraction
    101348250
  09154 Digestive system
   04970 Salivary secretion
    101348250
   04971 Gastric acid secretion
    101348250
   04972 Pancreatic secretion
    101348250
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101348250
   04961 Endocrine and other factor-regulated calcium reabsorption
    101348250
  09156 Nervous system
   04724 Glutamatergic synapse
    101348250
   04727 GABAergic synapse
    101348250
   04725 Cholinergic synapse
    101348250
   04728 Dopaminergic synapse
    101348250
   04726 Serotonergic synapse
    101348250
   04720 Long-term potentiation
    101348250
   04730 Long-term depression
    101348250
   04723 Retrograde endocannabinoid signaling
    101348250
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101348250
  09158 Development and regeneration
   04360 Axon guidance
    101348250
  09159 Environmental adaptation
   04713 Circadian entrainment
    101348250
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101348250
   05206 MicroRNAs in cancer
    101348250
   05205 Proteoglycans in cancer
    101348250
   05207 Chemical carcinogenesis - receptor activation
    101348250
   05231 Choline metabolism in cancer
    101348250
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101348250
   05214 Glioma
    101348250
   05223 Non-small cell lung cancer
    101348250
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101348250
   05161 Hepatitis B
    101348250
   05171 Coronavirus disease - COVID-19
    101348250
   05164 Influenza A
    101348250
   05163 Human cytomegalovirus infection
    101348250
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101348250
   05143 African trypanosomiasis
    101348250
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    101348250
   05022 Pathways of neurodegeneration - multiple diseases
    101348250
  09165 Substance dependence
   05031 Amphetamine addiction
    101348250
   05032 Morphine addiction
    101348250
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101348250
   05415 Diabetic cardiomyopathy
    101348250
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101348250
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101348250
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tmu01001]
    101348250
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tmu04131]
    101348250
Enzymes [BR:tmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     101348250
Protein kinases [BR:tmu01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   101348250
Membrane trafficking [BR:tmu04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    101348250
SSDB
Motif
Pfam: Pkinase C1_1 PK_Tyr_Ser-Thr C2 C1_2 ABC1
Other DBs
NCBI-GeneID: 101348250
NCBI-ProteinID: XP_004374255
UniProt: A0A2Y9DGJ5
LinkDB
Position
Unknown
AA seq 549 aa
MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNEAFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRKPSNSLDRVKLTDFNFLMVLGKGSFGKVMLADRKGT
EELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVN
GGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIAD
FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQVMFHCN
FMFVYCCIM
NT seq 1650 nt   +upstreamnt  +downstreamnt
atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcatgaggtgaaggaccacaaattcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggtgcacaagaggtgccatgag
ttcgttactttttcttgcccgggtgcggataagggacccgacacagatgacccgaggagc
aagcacaagtttaaaatccacacttatggaagccccaccttctgtgatcactgtgggtca
ttgctatatggacttatccaccaagggatgaaatgtgacacctgcgacatgaatgttcac
aagcagtgtgtaatcaatgtccccagcctctgtggaatggatcacacagagaagcgaggg
cgcatctacctgaaggctgaagtcactgatgagaagctccacgtcacagtacgagatgca
aaaaatctaatccctatggatccaaatgggctttcagatccttacgtgaagctgaaactt
attcctgatcctaaaaatgaaagcaaacagaaaaccaaaaccatccgctctacactaaac
cctcagtggaatgaggccttcacgttcaaattaaagccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaagaaatgacttcatgggatccctttcc
tttggagtttcagagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa
gaagagggtgagtactacaatgtacccattccagaaggggatgaagaaggaaacgtggag
ctcaggcagaaatttgagaaagccaagctcggccccgctgggaacaaagtaatcagtcct
tcagaagacaggaaaccttccaacagcctcgaccgagtgaaactcactgacttcaatttc
ctcatggtcctggggaaagggagttttggaaaggtgatgcttgctgacaggaaaggcaca
gaagagctgtacgctatcaagatcctcaagaaggacgtggtgatccaggatgacgacgtg
gagtgcaccatggtagagaagagagttctggccctccttgacaaacctccattcctgaca
cagctccactcctgcttccagacagtggatcgactgtacttcgtcatggaatatgtcaac
ggtggggacctcatgtaccacattcagcaagtcggaaaatttaaggagccacaagcagta
ttctatgcagcagagatttccattggattgttctttcttcataaaaggggaatcatttat
agagatctaaaattagataatgtcatgctggattcagaaggacatatcaagattgcagac
tttgggatgtgtaaggagcacatgatggatggcgtcacaaccaggaccttctgtgggact
ccagattacatcgccccagagataatcgcttatcagccgtatgggaaatccgtggactgg
tgggcgtatggcgtcctgttatacgaaatgctagctggccaggtaatgtttcactgcaat
tttatgtttgtttattgctgtataatgtga

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