Trichechus manatus latirostris (Florida manatee): 101348250
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Entry
101348250 CDS
T05135
Name
(RefSeq) protein kinase C alpha type isoform X2
KO
K02677
classical protein kinase C alpha type [EC:
2.7.11.13
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01521
EGFR tyrosine kinase inhibitor resistance
tmu04010
MAPK signaling pathway
tmu04012
ErbB signaling pathway
tmu04014
Ras signaling pathway
tmu04015
Rap1 signaling pathway
tmu04020
Calcium signaling pathway
tmu04066
HIF-1 signaling pathway
tmu04070
Phosphatidylinositol signaling system
tmu04071
Sphingolipid signaling pathway
tmu04072
Phospholipase D signaling pathway
tmu04150
mTOR signaling pathway
tmu04151
PI3K-Akt signaling pathway
tmu04261
Adrenergic signaling in cardiomyocytes
tmu04270
Vascular smooth muscle contraction
tmu04310
Wnt signaling pathway
tmu04360
Axon guidance
tmu04370
VEGF signaling pathway
tmu04510
Focal adhesion
tmu04540
Gap junction
tmu04613
Neutrophil extracellular trap formation
tmu04650
Natural killer cell mediated cytotoxicity
tmu04664
Fc epsilon RI signaling pathway
tmu04666
Fc gamma R-mediated phagocytosis
tmu04670
Leukocyte transendothelial migration
tmu04713
Circadian entrainment
tmu04720
Long-term potentiation
tmu04723
Retrograde endocannabinoid signaling
tmu04724
Glutamatergic synapse
tmu04725
Cholinergic synapse
tmu04726
Serotonergic synapse
tmu04727
GABAergic synapse
tmu04728
Dopaminergic synapse
tmu04730
Long-term depression
tmu04750
Inflammatory mediator regulation of TRP channels
tmu04911
Insulin secretion
tmu04912
GnRH signaling pathway
tmu04916
Melanogenesis
tmu04918
Thyroid hormone synthesis
tmu04919
Thyroid hormone signaling pathway
tmu04921
Oxytocin signaling pathway
tmu04925
Aldosterone synthesis and secretion
tmu04926
Relaxin signaling pathway
tmu04928
Parathyroid hormone synthesis, secretion and action
tmu04929
GnRH secretion
tmu04933
AGE-RAGE signaling pathway in diabetic complications
tmu04935
Growth hormone synthesis, secretion and action
tmu04960
Aldosterone-regulated sodium reabsorption
tmu04961
Endocrine and other factor-regulated calcium reabsorption
tmu04970
Salivary secretion
tmu04971
Gastric acid secretion
tmu04972
Pancreatic secretion
tmu05017
Spinocerebellar ataxia
tmu05022
Pathways of neurodegeneration - multiple diseases
tmu05031
Amphetamine addiction
tmu05032
Morphine addiction
tmu05143
African trypanosomiasis
tmu05146
Amoebiasis
tmu05161
Hepatitis B
tmu05163
Human cytomegalovirus infection
tmu05164
Influenza A
tmu05170
Human immunodeficiency virus 1 infection
tmu05171
Coronavirus disease - COVID-19
tmu05200
Pathways in cancer
tmu05205
Proteoglycans in cancer
tmu05206
MicroRNAs in cancer
tmu05207
Chemical carcinogenesis - receptor activation
tmu05214
Glioma
tmu05223
Non-small cell lung cancer
tmu05225
Hepatocellular carcinoma
tmu05231
Choline metabolism in cancer
tmu05415
Diabetic cardiomyopathy
tmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101348250
04012 ErbB signaling pathway
101348250
04014 Ras signaling pathway
101348250
04015 Rap1 signaling pathway
101348250
04310 Wnt signaling pathway
101348250
04370 VEGF signaling pathway
101348250
04066 HIF-1 signaling pathway
101348250
04020 Calcium signaling pathway
101348250
04070 Phosphatidylinositol signaling system
101348250
04072 Phospholipase D signaling pathway
101348250
04071 Sphingolipid signaling pathway
101348250
04151 PI3K-Akt signaling pathway
101348250
04150 mTOR signaling pathway
101348250
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101348250
04540 Gap junction
101348250
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
101348250
04650 Natural killer cell mediated cytotoxicity
101348250
04664 Fc epsilon RI signaling pathway
101348250
04666 Fc gamma R-mediated phagocytosis
101348250
04670 Leukocyte transendothelial migration
101348250
09152 Endocrine system
04911 Insulin secretion
101348250
04929 GnRH secretion
101348250
04912 GnRH signaling pathway
101348250
04921 Oxytocin signaling pathway
101348250
04926 Relaxin signaling pathway
101348250
04935 Growth hormone synthesis, secretion and action
101348250
04918 Thyroid hormone synthesis
101348250
04919 Thyroid hormone signaling pathway
101348250
04928 Parathyroid hormone synthesis, secretion and action
101348250
04916 Melanogenesis
101348250
04925 Aldosterone synthesis and secretion
101348250
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101348250
04270 Vascular smooth muscle contraction
101348250
09154 Digestive system
04970 Salivary secretion
101348250
04971 Gastric acid secretion
101348250
04972 Pancreatic secretion
101348250
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
101348250
04961 Endocrine and other factor-regulated calcium reabsorption
101348250
09156 Nervous system
04724 Glutamatergic synapse
101348250
04727 GABAergic synapse
101348250
04725 Cholinergic synapse
101348250
04728 Dopaminergic synapse
101348250
04726 Serotonergic synapse
101348250
04720 Long-term potentiation
101348250
04730 Long-term depression
101348250
04723 Retrograde endocannabinoid signaling
101348250
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101348250
09158 Development and regeneration
04360 Axon guidance
101348250
09159 Environmental adaptation
04713 Circadian entrainment
101348250
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101348250
05206 MicroRNAs in cancer
101348250
05205 Proteoglycans in cancer
101348250
05207 Chemical carcinogenesis - receptor activation
101348250
05231 Choline metabolism in cancer
101348250
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101348250
05214 Glioma
101348250
05223 Non-small cell lung cancer
101348250
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101348250
05161 Hepatitis B
101348250
05171 Coronavirus disease - COVID-19
101348250
05164 Influenza A
101348250
05163 Human cytomegalovirus infection
101348250
09174 Infectious disease: parasitic
05146 Amoebiasis
101348250
05143 African trypanosomiasis
101348250
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
101348250
05022 Pathways of neurodegeneration - multiple diseases
101348250
09165 Substance dependence
05031 Amphetamine addiction
101348250
05032 Morphine addiction
101348250
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101348250
05415 Diabetic cardiomyopathy
101348250
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101348250
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101348250
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tmu01001
]
101348250
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tmu04131
]
101348250
Enzymes [BR:
tmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
101348250
Protein kinases [BR:
tmu01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
101348250
Membrane trafficking [BR:
tmu04131
]
Endocytosis
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
101348250
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
C1_1
PK_Tyr_Ser-Thr
C2
C1_2
ABC1
Motif
Other DBs
NCBI-GeneID:
101348250
NCBI-ProteinID:
XP_004374255
UniProt:
A0A2Y9DGJ5
LinkDB
All DBs
Position
Unknown
AA seq
549 aa
AA seq
DB search
MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS
LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA
KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNEAFTFKLKPSDKDRRL
SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE
LRQKFEKAKLGPAGNKVISPSEDRKPSNSLDRVKLTDFNFLMVLGKGSFGKVMLADRKGT
EELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVN
GGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIAD
FGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQVMFHCN
FMFVYCCIM
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc
gcccgcaaaggggcgctgaggcagaagaacgtgcatgaggtgaaggaccacaaattcatc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt
gggaaacaaggcttccagtgccaagtttgctgttttgtggtgcacaagaggtgccatgag
ttcgttactttttcttgcccgggtgcggataagggacccgacacagatgacccgaggagc
aagcacaagtttaaaatccacacttatggaagccccaccttctgtgatcactgtgggtca
ttgctatatggacttatccaccaagggatgaaatgtgacacctgcgacatgaatgttcac
aagcagtgtgtaatcaatgtccccagcctctgtggaatggatcacacagagaagcgaggg
cgcatctacctgaaggctgaagtcactgatgagaagctccacgtcacagtacgagatgca
aaaaatctaatccctatggatccaaatgggctttcagatccttacgtgaagctgaaactt
attcctgatcctaaaaatgaaagcaaacagaaaaccaaaaccatccgctctacactaaac
cctcagtggaatgaggccttcacgttcaaattaaagccttcagacaaagaccgacgactg
tctgtagaaatctgggactgggatcgaacaacaagaaatgacttcatgggatccctttcc
tttggagtttcagagctgatgaagatgccggccagtggatggtacaagttgcttaaccaa
gaagagggtgagtactacaatgtacccattccagaaggggatgaagaaggaaacgtggag
ctcaggcagaaatttgagaaagccaagctcggccccgctgggaacaaagtaatcagtcct
tcagaagacaggaaaccttccaacagcctcgaccgagtgaaactcactgacttcaatttc
ctcatggtcctggggaaagggagttttggaaaggtgatgcttgctgacaggaaaggcaca
gaagagctgtacgctatcaagatcctcaagaaggacgtggtgatccaggatgacgacgtg
gagtgcaccatggtagagaagagagttctggccctccttgacaaacctccattcctgaca
cagctccactcctgcttccagacagtggatcgactgtacttcgtcatggaatatgtcaac
ggtggggacctcatgtaccacattcagcaagtcggaaaatttaaggagccacaagcagta
ttctatgcagcagagatttccattggattgttctttcttcataaaaggggaatcatttat
agagatctaaaattagataatgtcatgctggattcagaaggacatatcaagattgcagac
tttgggatgtgtaaggagcacatgatggatggcgtcacaaccaggaccttctgtgggact
ccagattacatcgccccagagataatcgcttatcagccgtatgggaaatccgtggactgg
tgggcgtatggcgtcctgttatacgaaatgctagctggccaggtaatgtttcactgcaat
tttatgtttgtttattgctgtataatgtga
DBGET
integrated database retrieval system