Talpa occidentalis (Iberian mole): 119260772
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Entry
119260772 CDS
T07495
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00020
Citrate cycle (TCA cycle)
tod00190
Oxidative phosphorylation
tod01100
Metabolic pathways
tod01200
Carbon metabolism
tod04714
Thermogenesis
tod04932
Non-alcoholic fatty liver disease
tod05010
Alzheimer disease
tod05012
Parkinson disease
tod05014
Amyotrophic lateral sclerosis
tod05016
Huntington disease
tod05020
Prion disease
tod05022
Pathways of neurodegeneration - multiple diseases
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05415
Diabetic cardiomyopathy
Module
tod_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tod_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
tod_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
119260772 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
119260772 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
119260772 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
119260772 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
119260772 (SDHA)
05012 Parkinson disease
119260772 (SDHA)
05014 Amyotrophic lateral sclerosis
119260772 (SDHA)
05016 Huntington disease
119260772 (SDHA)
05020 Prion disease
119260772 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
119260772 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119260772 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
119260772 (SDHA)
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
119260772 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Pyr_redox_2
Thi4
DAO
GIDA
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
119260772
NCBI-ProteinID:
XP_037385730
LinkDB
All DBs
Position
Unknown
AA seq
662 aa
AA seq
DB search
MSGVRAVSRLLRHRRLALTRAPASRTGARGFHFTVDGTKRSSAKVSDSISAQYPVVDHEF
DAVVVGAGGAGLRAAFGLSEAGFSTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWH
FYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGK
GGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEGGECRGVIALCIEDG
SIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYG
AGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTVEIREGRGCGPEKD
HVYLQLHHLPPEQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVL
KHVDGRDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVP
PIKANAGEESVMNLDKLRFAEGSIRTSELRLNMQKSMQSHAAVFRLGSVLQEGCEKISRL
YGDLKHLRTFDRGMVWNTDLVETLELQNLMLCALQTIHGAEARKESRGAHAREDYKERVD
EYDYSKPIQGQQRKPFEQHWRKHTLSYVDIRTGKVSLQYRPVIDQTLDETDCATVPPAIR
SY
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggggtccgggcggtgtcgcggctgctccgccaccggcgcctggcgctgacccgc
gcgccggcatcacggacaggagcccgcgggtttcacttcacggtcgatgggacgaagagg
tcgtctgctaaggtgtcagactccatttccgcgcagtacccagttgtggaccatgagttc
gacgcggtggtggtgggcgctggcggcgctggcctgcgcgcagccttcggcctctcggag
gcgggcttcagcacagcatgtgtcacgaagctctttcccaccagatcccacactgtggcc
gcccagggaggcatcaatgccgcgctgggcaacatggaggaggacaactggaggtggcac
ttctacgacactgtgaagggctccgactggctgggggaccaggacgccatccactacatg
actgagcaggcccctgcctctgtggttgagctggagaactacggcatgccgttcagcagg
accgaggacgggaggatctaccagcgcgcctttggcgggcagagcctcaagttcggcaaa
ggcgggcaggcccatcgctgctgctgcgtggcagaccgcaccggccactcactgctgcac
acgttgtatggacggtctctgcggtatgacaccagctacttcgtggagtacttcgccctg
gacctcctgatggagggcggggagtgccgcggcgtgatcgcgctctgcatagaggacggg
tccatccaccgcattagagccaagaacacggtcatcgccacagggggctacgggcgcacc
tacttcagctgcacatctgctcacaccagcactggcgatggcaccgccatgatcaccaga
gccggcctgccctgccaggatctggagtttgtgcagttccaccccacaggcatctacggc
gccggctgtctcatcacggagggctgccgtggagaggggggcatcctcatcaacagccag
ggcgagcggttcatggagcggtacgcgcctgtcgccaaggacctggcgtcccgggacgtt
gtgtctcggtccatgaccgtggagatccgcgagggcagaggctgcggccccgagaaggac
cacgtctacctgcagctgcaccacctgccccccgagcagctggccatgcgccttcctggc
atctccgagacggccatgatcttcgcgggtgtggatgtcaccaaggagcccatccccgtc
ctccccaccgtgcactacaacatggggggcatccccaccaactacaaggggcaggttctg
aagcacgtggacgggcgggaccaggtggtccccggcctgtacgcctgtggggaagctgcc
tgtgcctcagtgcatggagccaaccggctgggagccaactcactgcttgacctggtggtg
ttcggccgcgcctgtgccctgagcatcgcggagtcctgcaggcccggagataaagttccc
ccaattaaagctaacgctggggaagaatctgtcatgaatcttgacaaattgcggtttgct
gagggaagcataagaacctcagaactgcgactcaacatgcagaagtccatgcagagccat
gcggcggtgttccggttgggcagcgtgctgcaggagggctgtgagaagatcagccggctc
tatggggacctgaagcatctgaggacgttcgacagagggatggtctggaacacggacctt
gtggagaccctggagctgcagaatttgatgctgtgcgcgctgcagaccatccacggcgcc
gaggcccgcaaggagtcgcgcggcgcccatgcccgggaggactacaaggagcgggtagac
gagtatgactactcgaagcctatccaggggcagcagcggaagcccttcgagcagcactgg
cggaagcacaccctttcctacgtcgacatccggaccgggaaggtctcgctacagtacagg
cccgtgatcgaccagactctggatgagactgactgtgccacggtgcccccggccatccgc
tcctactga
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