Treponema pallidum subsp. pallidum Sea 81-4: TPSea814_000670
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Entry
TPSea814_000670 CDS
T03185
Symbol
ddl
Name
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tpas
Treponema pallidum subsp. pallidum Sea 81-4
Pathway
tpas00470
D-Amino acid metabolism
tpas00550
Peptidoglycan biosynthesis
tpas01100
Metabolic pathways
tpas01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tpas00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TPSea814_000670 (ddl)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TPSea814_000670 (ddl)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TPSea814_000670 (ddl)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tpas01011
]
TPSea814_000670 (ddl)
Enzymes [BR:
tpas01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TPSea814_000670 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:
tpas01011
]
Precursor biosynthesis
Amino acid ligase
TPSea814_000670 (ddl)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
AHN67333
UniProt:
A0AA86E510
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All DBs
Position
complement(735447..736637)
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AA seq
396 aa
AA seq
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MVHVTLLYGGRSAEHDVSVRSARFVARTLCLQHTVMLIGITRRGVWYAQPACALEQLCTG
TVALSIQEDEKRRVCLVPGGGTAGAFVIAGMPCVTDVVFPVLHGSYGEDGTVQGLLEMLQ
VPYVGCGVCASALAMDKVKAKMLWQAAGLPVLPFVFFRKDAWRMHMQEFVAQLETRLGYP
LFVKPAQAGSSVGASAVQTRAPLIPAIEAAFQWDEVVLVERYVRAREIECALSGNGPYTV
HGAGEVIAQGAFYDYEEKYADASVARVLVTAPLETAQYEQITTLALRAYEALGLTGLARV
DFFLLETGEVYVNEVNTMPGFTSISLFPQICQAAGVAPQDLMAQLLSCARERFAARAALS
TDLHAHVCAPSVTAAHDPDAQGDDWDQRDSNPLPTA
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
gtggtgcatgtgacgcttttgtacggaggccgttctgcagagcacgatgtttctgtacgt
tctgcacgttttgtggcgcgcacgttgtgcttacaacacaccgtaatgctcatcggtatt
acccgtcgtggcgtgtggtatgcgcagcctgcgtgtgcattagagcagttgtgtaccggc
actgtcgcgctcagtattcaggaagatgaaaagaggcgcgtgtgtcttgtcccgggaggt
ggtactgcaggcgcttttgtcatagcggggatgccgtgtgtcacggatgtggtattcccc
gtattgcatggcagttatggggaagatggtacggtgcagggtttgcttgagatgctgcag
gtgccgtacgtggggtgtggagtgtgtgcaagtgctcttgcgatggataaggtaaaggca
aagatgctatggcaggcggcgggacttcccgttttaccgtttgtctttttccgtaaagat
gcatggcgtatgcatatgcaagaatttgttgcgcagcttgaaacacgccttggctatcct
ctttttgtaaagccagctcaagcaggcagttccgtaggagccagtgcagtgcagacgcgt
gcaccgcttatccctgcgattgaagcggcttttcagtgggatgaagtggtgttggtggag
cgatatgtgcgcgcgcgagaaattgaatgtgcgctcagtgggaacggaccctatactgta
catggggcaggagaggtgattgcgcagggagccttttatgactacgaggaaaaatatgct
gatgcaagtgtcgcgcgtgtactcgttacggctcctcttgagactgcccagtacgaacag
attaccacacttgccctgcgcgcatacgaagcattaggactcacgggtctggcgcgggtt
gatttttttctgttagaaacgggagaagtatatgtgaacgaagtaaacacgatgccgggt
tttacgtcgatatcactctttccccaaatatgtcaggctgcaggtgttgcaccgcaggac
ttaatggcacaactcctttcttgcgcacgagagcgctttgcagcgcgcgccgcactgagc
accgacttgcacgcccacgtgtgtgcgccctcggtgactgctgcacatgaccccgatgcg
caaggggacgactgggaccagagggactcgaaccccctccctactgcttag
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