Tsukamurella paurometabola: Tpau_1211
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Entry
Tpau_1211 CDS
T01228
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
tpr
Tsukamurella paurometabola
Pathway
tpr00020
Citrate cycle (TCA cycle)
tpr00630
Glyoxylate and dicarboxylate metabolism
tpr00785
Lipoic acid metabolism
tpr01100
Metabolic pathways
tpr01110
Biosynthesis of secondary metabolites
tpr01120
Microbial metabolism in diverse environments
tpr01200
Carbon metabolism
tpr01210
2-Oxocarboxylic acid metabolism
Module
tpr_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tpr_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
tpr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Tpau_1211
00630 Glyoxylate and dicarboxylate metabolism
Tpau_1211
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Tpau_1211
Enzymes [BR:
tpr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Tpau_1211
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Tpau_1211
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Tpau_1211
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Tpau_1211
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ADG77842
UniProt:
D5UW35
LinkDB
All DBs
Position
complement(1236070..1239789)
Genome browser
AA seq
1239 aa
AA seq
DB search
MSSSSVSDFGQNEWLVEEMYERFKADPNSVDPSWHDFLSTYQPGAAAANGSAPAAAAAPA
APAAPAPAAAAPAVTPPAKAAESTLTPAPSKPVTPAPSSPAKPAPAPKTPATAEFPAEEE
HQVLRGAANAVVKNMNASREIPTATSVRAMPVKVMFDNRVVINNHLARTRGGKISFTHIL
GYALVQGVKAFPNMNRHFAEIDGKPNAVTPPHVNLGIAIDLVGKNGSRSLVVAGVKNAET
MDFAQFVAAYEDIVRRARNGKLTAEDFAGVTISLTNPGGIGTVHSVPRLMVGQGAIIGVG
AMEYPAEFQGASEEKIADLGVGKLTTLTSTYDHRIIQGAESGDFLRYVHELTLSDEFWDD
IFRTLHVPYEPVRWRRDIPPHGIDKDARVLELIAAYRARGHLMADVDPLRFNNDKLESHP
DLNVLTYELTLWDLDRTFNVGGFHGEDRLKLRKVLSVLRDAYCRHVGIEYAHILEPEQQK
WLQERVEAKDSKPSVAEQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAV
LDQAAEHSLDEVVIGMPHRGRLNVLANIVGKPYSKIFTEFEGNLNPAQAHGSGDVKYHLG
AEGKYYQMFGENEITVSLVANPSHLEAVDPVLEGIVHAKQDMLNPPEGTHPVMPLMLHGD
AAFAGQGVVAETLNMANLDGFSNGGTVHIVVNNQVGFTTSPENSRSSQYCTDVAKMIGAP
IFHVNGDDPEACVWVAKLAVDFRERFHKDVVIDLVCYRRRGHNEGDDPSMTQPGMYDVID
TKRGVRKSYTEALIGRGDISTKEAEDALRDYQGQLERVFNEVKELEKFQAEPAPSIIADQ
PLPSSLVTAVPLEQLQRIGDAYGNVPEGFTVHPRVAPVVKRRFEMSREGGVDWAFGELLA
FGTLLEEGRTVRLAGQDSRRGTFTQRHAVLIDRQSGQEYTPLDNLGPDGTPSPGKFMVYD
SALTEFAGLGFEYGYSVADESALVCWEAQFGDFVNGAQSIIDEFISSGEAKWGQTSGVTL
LLPHGHEGQGPDHTSARIERFLQLCAEGSMTVAMPSTPASYFHLLRRHALDGVRRPMVVA
TPKSMLRNKAAVSPLEDFTSGKFRSVIDDPAFEVDGGNRDGVSQLLLVSGKLYYELEARR
KKDNRTDVAIIRMEQLYPLPSRRLPATLDKYPNAKDVRWVQEEPANQGAWPFFGLELPQL
DERLVGIKRVSRRAMSAPCSGSSKVHAVEQAQIIDEAFA
NT seq
3720 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcagttctgtatcggatttcggccaaaacgagtggctggtcgaggagatgtac
gagcggttcaaggccgaccctaattcggtcgacccgagctggcacgatttcctctccacg
tatcagcccggcgccgccgcggcgaatggcagcgcacccgctgcggccgcagcgcctgcg
gcccccgccgctcccgctccggcggccgcggccccggcggtgaccccgcccgcgaaggcg
gccgagtccacgctgacgccggcaccgtcgaagccggtcactcccgccccgtcgtccccc
gcgaagccggcgccggcgccgaagactcccgccacggcggagttcccggccgaggaggag
caccaggtgctccgcggcgccgcgaatgcggtggtcaagaacatgaacgccagccgcgag
atcccgacggccacgtcggtgcgcgcgatgccggtgaaggtgatgttcgacaaccgcgtg
gtgatcaacaaccacctcgcgcgtacccgcggcggcaagatcagcttcacccacatcctc
gggtatgcgctggtccagggcgtcaaggcgttccccaacatgaaccggcacttcgccgag
atcgacggtaagccgaacgccgtcacaccaccgcatgtcaacctgggcatcgcgatcgac
ctggtgggcaagaacggaagccgcagcctggtggtggccggcgtcaagaacgccgagacc
atggacttcgcacagttcgtggccgcctacgaggacatcgtgcgccgggcccgcaacggc
aagttgaccgccgaggacttcgccggggtcaccatctcgctgaccaacccgggcggtatc
ggcacggtgcactcggtgccccgtctgatggtgggccagggcgcgatcatcggcgtcggt
gccatggagtacccggccgagttccagggcgccagcgaggagaagatcgccgatctggga
gtcggcaagctcaccacgctgacctcgacctacgaccaccgcatcattcagggcgccgag
tcgggcgacttcctgcgctacgtccacgagctcaccctgagcgacgagttctgggacgac
atcttccgcaccctgcacgtgccctacgagcccgtgcgctggcgtcgcgacatccccccg
cacggcatcgacaaggacgcccgcgttcttgagctgatcgcggcctaccgggcccgcggc
cacctgatggccgatgtggatccgctgcggttcaacaacgacaagctcgaatcgcacccc
gacctgaacgtgctcacctacgagctgacgctgtgggatctggaccgcacgttcaacgtg
ggtggtttccacggcgaagaccggctcaagctgcgcaaggtgctctcggtgctgcgcgac
gcctactgccggcacgtgggtatcgagtacgcgcacatcctcgagcccgagcagcagaag
tggctgcaggagcgcgtcgaggccaaggattccaagccctcggtcgccgagcagaagtac
atcctgtccaagctcaacgccgccgaggccttcgagacgttcctgcagaccaagtacgtc
ggccagaagcggttctcgctggagggcgccgagtcggtcatcccgatgatggacgccgtc
ctcgatcaggccgccgagcactcgctcgatgaggtcgtgatcggcatgccgcaccgcggc
cgcctcaacgtgctggcgaacatcgtcggcaagccgtacagcaagatcttcaccgagttc
gagggcaacctgaacccggcgcaggcacacggctcgggtgacgtgaagtaccacctcggc
gccgagggcaagtactaccagatgttcggcgagaacgagatcaccgtctcgctggtcgcc
aacccgtcgcacctcgaagcggtcgaccccgtgctcgagggcatcgtgcacgccaagcag
gacatgctgaacccgccggagggcacgcaccccgtcatgccgctgatgctgcacggcgac
gccgccttcgccggtcagggcgtggtggccgagacgctcaacatggcgaacctcgacggc
ttctccaacggcggcaccgtgcacatcgtggtgaacaaccaggtcggcttcaccacctcg
ccggagaactcccgcagctcgcagtactgcaccgatgtggcgaagatgatcggcgcgccg
atcttccacgtcaacggcgacgatcccgaggcctgcgtgtgggtggccaagctcgccgtc
gatttccgcgagcgcttccacaaggacgtcgtgatcgacctcgtctgctaccgccgccgc
ggccacaacgagggcgacgatccgtcgatgacccagcccggcatgtacgacgtgatcgac
accaagcgcggtgtccgcaagtcctacaccgaggctctgatcggccgtggcgacatctcc
accaaggaggccgaggacgcactgcgcgactaccagggccagctggagcgggtgttcaac
gaggtcaaggagctcgagaagttccaggccgagcccgcaccgtcgatcatcgccgaccag
ccgctgcccagctcgctggtgaccgccgtaccgctggagcaattgcagcggatcggcgac
gcctacgggaatgtgcccgagggcttcaccgtgcacccgcgcgtggcccccgtggtcaag
cgtcggttcgagatgtcgcgcgagggcggcgtcgactgggcgttcggtgagctcctcgcg
ttcggcaccctgctggaggagggccgcacggtccgcctggccggccaggacagccgccgc
ggcaccttcacgcagcgtcacgcggtgctgatcgatcgccagtccgggcaggagtacacc
ccgctcgacaacctcggccccgacggcaccccgtcgcccggcaagttcatggtctacgac
tcggcgctcaccgagttcgcgggcctgggcttcgagtacggctactcggtggccgacgag
tcggcgctggtgtgttgggaggcgcagttcggcgacttcgtcaacggcgcgcagtcgatc
atcgacgaattcatcagctcgggagaggccaagtggggccagacctcgggcgtcacgctg
ctgctcccccacggccacgagggccaggggcccgaccacacctcggcccgtatcgagcgg
ttcctgcagttgtgcgccgagggctcgatgacggtcgcgatgccgtcgacccccgcgtcg
tacttccacctgttgcgccgccacgcgctcgacggtgtgcgccgcccgatggtggtcgcg
acgccgaagtcgatgctgcgcaacaaggcggcggtgagcccgctggaggacttcacctcg
ggcaagttccgttcggtgatcgacgatccggccttcgaggtcgacggcggcaaccgcgac
ggcgtgtcccagctcctgctggtctccggcaagctgtactacgagctggaggctcgccgg
aagaaggacaaccgcaccgacgtggcgatcatccgcatggagcagctctacccgctgccc
tcgcggcgcctgccggccacgctggacaagtaccccaacgcgaaggacgtgcgctgggtg
caggaggagccggccaaccaaggtgcgtggccgttcttcggcctggagctgccgcagctc
gacgagcgcctcgtgggcatcaagcgcgtctcgcggcgcgccatgtcggcaccgtgctcg
ggttcgtcgaaggtgcacgcggtggagcaggcacagatcatcgacgaggccttcgcctga
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