Thermomicrobium roseum: trd_0065
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Entry
trd_0065 CDS
T00845
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tro
Thermomicrobium roseum
Pathway
tro00470
D-Amino acid metabolism
tro00550
Peptidoglycan biosynthesis
tro01100
Metabolic pathways
tro01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tro00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
trd_0065
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
trd_0065
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
trd_0065
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tro01011
]
trd_0065
Enzymes [BR:
tro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
trd_0065
Peptidoglycan biosynthesis and degradation proteins [BR:
tro01011
]
Precursor biosynthesis
Amino acid ligase
trd_0065
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GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
ACM05555
UniProt:
B9L283
LinkDB
All DBs
Position
74622..75740
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AA seq
372 aa
AA seq
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MARKIRVAVIFGGQSGEHDVSLRSARAILRHIDRERFEIVPVGITREGRWLIGGDPLREL
ATASRLPLELEPVSSGAGSAPATGESALALPGSLPGEIDVVFPVLHGPYGEDGTIQGLLE
LAGIPYVGCGVLASAVAMDKPTAKRLFASVGLEQARWIAFTWHEWQCQHQTLLARIEREL
GYPCFVKPANLGSSVGVSKARRREELLAAIELASRYDRRIVVEEAIDARELEVSVLGNEE
PVASIVGEIVPSREFYDYEAKYIDPHSQLLIPAPISEEQAATVRRMALEAFRVIDGAGMA
RVDFFLERSTGRILINEVNTIPGFTAISMYPKLWEASGLCFRDLITRLIELALERHQAQQ
RRRAQATQPFSG
NT seq
1119 nt
NT seq
+upstream
nt +downstream
nt
atggccaggaaaatccgcgttgcagtcattttcggcgggcagtcgggtgagcacgatgtc
tccttgcgctcggcccgagcgatcctgcgtcacatcgatcgtgagcgcttcgagatcgta
ccagtcgggatcacgcgcgagggccgctggctgatcggaggcgatccgctgcgcgagttg
gccacagcgagccgtctgccgctcgagctggaaccggtcagcagtggggcgggcagcgct
ccggcaacgggtgagagcgcgcttgcccttccggggtcgctgcctggtgagatcgatgtc
gtctttccggtgctccacgggccgtacggggaggacgggacgatccagggactcctggag
ttggccggcatcccctacgtcggttgcggtgtcctcgcctcggcggtcgccatggacaag
ccgacggcgaagcgactcttcgcgagcgtgggactcgagcaggctcgctggatcgctttc
acctggcacgagtggcagtgccagcaccagacgctcctcgcgcggatcgaacgggaactc
ggttatccctgcttcgtcaagccggctaatctcggctccagtgtcggcgtgagcaaagcg
cgcaggcgcgaggagcttctggccgcgatcgagttggcgagccgttacgatcgtcgcatc
gtcgtggaagaagcgatcgatgcacgggaactggaggtgagcgtcctcggcaacgaggaa
ccggtcgcctcgatcgtgggagagatcgtcccgagtcgcgagttttacgactacgaggcg
aagtacatcgacccccactctcagctcctcattccggcaccgatcagtgaggagcaggcg
gcaacggtccgacggatggcgttggaagcgtttcgggtgatcgacggtgcgggaatggct
cgcgtggacttcttcctggaacgctcgactggccggattttgatcaacgaggtcaatacg
atacccgggttcaccgcgatctccatgtatcccaagctctgggaggcatcgggactgtgc
tttcgggatctgatcacgcggttgatcgagctcgccctggagcggcaccaggcgcagcag
cggcgacgagctcaggcgacccagccgttctccggttga
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