Takifugu rubripes (torafugu): 101063467 Help Entry 101063467         CDS       T02386                                  Name (RefSeq) obscurin-like   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism tru  Takifugu rubripes (torafugu) Pathway tru04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:tru00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     101063467  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tru01001]     101063467   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:tru04131]     101063467 Enzymes [BR:tru01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      101063467 Protein kinases [BR:tru01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    101063467 Membrane trafficking [BR:tru04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     101063467 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 Izumo-Ig RhoGEF V-set_CD47 fn3 Kdo PH Lep_receptor_Ig IQ IQ_SEC7_PH Motif Other DBs NCBI-GeneID:  101063467 NCBI-ProteinID:  XP_029684277 LinkDB All DBs Position 20:complement(9765886..9795303) Genome browser AA seq 6309 aa AA seqDB search MGDSKHPGKVAAAKNHLQVVKGLEDAEVSECESCSFEVTLSVAYIAGVWTRDGTQLRSKP SCCISTHGKKHSLILKRVTLGDAGLYCFQADGLQTSGRLGVRARDIYIVKELEDVDTRER QTVNFLCEVNQVDVDGRWYRDDCRIRPGDKIKIRHQGRTHTLCFKSVRPEHAGEIRFTAE RVSSYATLTVKELPVQIVRPLRVKIAMYRHRGLLECQVSRPNAQVKWYKNRKELLPSKKY QVINQDVYRQLYIDDVCSSDEDTYTCDAGDDQTSCQLLVEEQAISIVRGMSSVEVMEPEP ALFQVETSLKSGRPPRWTLNGEVLEPSAAVNINRKGTVHSLCLTSTESSMCGPVVFVAGK SRSTAQLTVKERPLQVSHPLEDTDAKENSSATLSCGFMPSPRVVRWFKGRTALKTSNKYS MKREGHRAELTIHGLTGMDSGQYRCVAGGSQSTAQVKVEVRTLKLVKHLEPVEVEEDGCA TFSCELNFVVANAEWLLNNVRLYSNAINRIQHMGTMHSLTIKKLRPQVGRVTFKAGLLSE SALLKVKERPAVFLKSLEDAVGEEQGDVCLHCEISKETATPVWRKDGFVLTPDDKHELLQ FGKTLALIIHSLSKDDAGQYTCDLGTSQTKAKVTVHDLHITIVQRLKTVSVLEGENCTFD CHLSHDVDDQPRWTINGQVVDTDGHVQVVNNGRRYRLAIKDALLSDAGDIVFTIKDLTCR TMLFVKEKPVHIFRDLLNVKAVPGEDAELSCEITKTDVTIRWLKNGHLIRQSPKYEMSVA KNQAKLVIRNATIRDSGDYCCEADGVASRAKVEIRELQHTFAMELKDSRAEEKAKVTLEC ETRRPAKRVKWLKGMLELRSSRKYVIRQKGVMLSLTINSLEKSDTDIYICDVGTMQSRAQ LTVQGQTVFILDELEDVECLEGDTVTFRCRICPSDYSDVKWYLDETLLYTNELNEIQLLA GGYHVLTFRQLARKDTGTISFSAGDKRSYASLLVRERRPTIIKALEDCEAIEGGGLILSC LTSKPCHIRWYKDGCLMWNSSRYFTSRSGCEARLTIREVGRNDGGVYECSAGSVSTRAVV TVKAIPAEFTQPLKSVEAREGETLTLTCEYSLPGIHFLWNKGYESIRPGDKYLMKQRKTV ISLTIQNLHPEDSGEYTCQCRDHRTTASLKVHAIPTTFTQQLRNIQAQEGSNVVLRCELS KPGIPVEWRKGDEPLKNGVRFQIRRRETTLELLIWKPVPEDSGVYSCVCADQKTSANVKI TALPVTFKQKLKNVQIEEGNVAVFRCELSKVGHSVEWMKRGDEVIRGGEKYQMRQRDTLL ELRILDAKPDDSNIYTCVCGTVETTATLTVNALPVTFKQKLKNVQVEEGNNITLYCEISK PGIPVEWRRAGDLLENGDKYHIRQRETTLELTIRDVDPEDSGVYTCACRDQRTKATVKVV AVPATFKVSLKSQDAEEGSSVSLSCELSKKGVLVQWKRDAQVLSEGMCPGKYQMKVEGKT AQLTVHSVQAEDAGRYSCIAGDEKTSAEVRVKALPVTFKRGVQNIAVKEGDSGVLCGELS RPGAQAEWRKGRVVLTPGEKFEMKQEGCFVKLLINCVEESDAGKYTCKTNDSQSTAELTV HGLPPTFRRPLINQEVMEGNSVILHCELSKAASSVEWRRGGELLKHGDKYQVRKKELQVE MKILDLSVSDGGEYSCVCGEQATRAVITVKEWPIRFLQELKNIQVQEGNEVKLRCEISKA GASIEWKKGEKVLSDGEKYRMKQSGSMLELVIRKSQPEDSGTYSCVCAEVKSSATIIITA IPITFKQKLKNQEVVEEGSVTLRCELSKAGVPVEWRKEAQLLQEGEKYQMRQEGRAAEMS IRGVTLADGGEYSCSVGTAVTAAEIKVRALPITFKQEMENLVVKEGDSAVFNCELSKPGA PVDWRKGRVVLKPGYKYEMKLEGRLSQLTINNIEESDAGKYTCKTSDSQSTAELTVRAPP IMFKTKLRSQQVEEEKSVTLSCELSKPGLAAQWRKGQEQLQNNFKYQIRNRNSIMELTIK NTQLVDSGLYSCNYGDVKTSANITVTPIPLSFKTGLKNQEAPEGGNVSLRCELSRTGVPV QWFKSENELCQGGRYQMTLGGNIAEMHIRNIQPEDVGEYSCIFGEQKTTAEVNVRAAASV YFEKELESQAVMEGKPVLLSCEVSSANVPVTWKKDNIVLEDGGRYILKKEGTRHSLEIRK LQLEDAGEFCCISRGKKTTAKLVVRERVRILTALQDITVTAGQDATFVCELTHAEAEGVW WLGSSPLQRNEMNQMMCQGRQHRLVLAMTTPEETGTVAFVVGEERTSAHLLVVPKPKVLF EEKPRDVVIMEGETAILSCVTTDLTSPVTWKCNHVPLRNGDKYETRKEGKVNLLLIHDAD PENAGIYSCDTGDVQSSARLTVTERPPFFQEGLQSVEVEEGGSVFLCCELSKLGVPIHWK KDRLPLRSSRKHEIKEDGCFLQLHVWDLKPEDSGSYSCQAGNAETTATVTVKELPPFFKK ELRNLGVEEGSSASLCCELSKPGVAVQWKRNRIPLRAGRKYEMKQEGCLLQLQIRDLIPE DSGSYSCHTESAETSASLSVKELPPIFTECLQNVTANEGGTLALRCELSKPGVAVQWKKN KVVLRSSRKYDMKHGGCLHQLNIGELTLEDNGSYSCHAGSAETAAVVSVKALPPFFKEGL QSVKVEEGGAASLSCVLSKPGVSVQWKKNKLVLRSSRKYEIKQDGCILQLQINGLKPEDS GSYSCHAGDAETTATVSVTEVPPFFKKDLINVEADEGGAASLCCELSKPGVSVQWKKNRI PLRAGRKYEMKQEGCILQLLIRDLIPEDSGSYSCQAEMLESTAVVTVKERAVFFSSDLQS VEAEEGGAVTLCCELSKPGVSVQWKKNSLQLRANRKYEMKQDGCLLQLHIKDLIPGDSGS YLCHAGGAETSATLSVRELPPFFKKSLESLEVEEGSSASLRCELSKPGASVQWTKNRILL RAGRKYEMKQEGCLLQLQINELIPEDSGSYSCHADSVVTTATVAVKELPPYFISQLQSVE AEEGSAASLCCELSKPGVRVQWKKNRIPLRAGRRCELKQEGCLLQLNIQELKPEDSGVYT CQTGSAETSATVSVKELPPFFKKTLQSVKAEEGATVSLCCELSKPGASVQWKKNEMALRA GRKYEMKQDGCLTELQIKDLKLEDSGSYSCHAGKAGTSATLAVRELPPFFKKSLQSLEVE EGSSASLCCELSKPGASVQWKKNRTPLRAGRKYEMKQEGCLLQLQINELIPEDSGSYSCH AGNAETSATVAVKELPPYFISQLQSVEAEEGSAASLCCELSKPGVRVQWKKNRIPLRAGR KYELKQEGCLLQLNIQELKPEDSGVYTCQTGSAETSATVSVKEIQPPPAKEEPPVIVSQT VAKPLKASTPAENVRPVPPEPKKRSNRKASITSLEKDAILTLDKNQSVVKDRKEELKGTP ARSEEKDLGVLKNGTRAEEFNLEKDEAKNFDKFTKLTDIKKELVGEAKKKREKDVFIEAE QPATILEKLVLAEQPEVVLEQKRRSFVCLQNEDEGEVIPKQPAKPSEKENKVDTKRPSPA FQEEMPGKEDQDDVRGPLKQQEARSAVQKEGDKTEESFKPPVRSRGRLTLENQQPNMDLF QPEKALEVSEEGLEQRNQVKQGLSTTVSQKEKTGQKSQEKLDKTLANQVEHAPPKPPTRL KSKARSGMEKQHSRDTETEQDDQQVKVDDRLVNKSVSLKKEAEEKPNFESEQWVTEIPEQ FKQPAKVSDNDTNTKQSLKQLVKPIIKEPEQETKLAVRPLRREEEQHVTKQAEDIPLLYI SEDETFMEALSELPVDIQPPDQGFTTNPPEDATLDDEPELQGAAVKIQAAFKGYKTRKDM RPVFKEVFKNQSADLQSTLTLLCVVEGNPTTVRWLKNGHSIVSDHRCCMETTEAGACSLV IKNLGSADSGVYTCEAVNKFGIASYNGNITVVQPQKPLQKPVHPPLAAITPLQLAQPKSD SQPKSPLQNQHLAQAQGQTGTESYVESVNVSLWEAYNLTEQQDTPMRLQERRASLLAASS MSSPSDYDTAPDVMEPVDAPVLREAKQANAADRVLPKEDKEQITPPQTLKHLKVKDHEDR LRTASPKHHRAHTPLTSTVSGSESEGEEDRQETFEMYVTRADCSSEGGNKDSVVLKEGQF VEVLDAFHPERWLVRTKPTKTNPARQGWVCPAYLEKKRKETFPQLRPQAEDLDGIGSTGE EYRRSLSQLIQGLIDGEEEFVKEMKTLQLHYLDSSRHVSVNILNQKEMIFRNIKDIVCLH ERSILPGLRECTTDDDVAMLLISHAENFEKYLHYMVGQAQAEACIADKAVQQYFKESAES SAAPAMDVLTFIQQPVERIQTYQALLKELIKNKAKSGQSCCLLEKSFSMMSSLPWRSDNL HQVSLIENYPAPLTALGEPVRQGVFTVWEENPEVKVSSRGHQRQVFLFKECIVLCKLKRD GSVNADTFTFKNKMKLNDVEIKESVDGDEKSWGLWHEHRGSLRRYTLQGRSSLVKLSWLK DLKELQQRTSLPTNTPPVFESLLSDWTTKIGQTIKLTCKVTGSPTPAVSWFKDGLSLEDD PRHIILAERSGTCTLILDSLSAQDSGQYACFAHSFMGSAGTLAKVVVQAPPRFVSRLESA CLIEGEDIQFSCSTLTTPLPRIRWSKEGRELFNGEKYCILNDARSGILSLTVIGATEADI GQYECELWNEFGCVRCKAGLCPAYVPPTDVESDHPQDLPAKDADSDSWTTAFVNKWLQSD FNPAPAAKMLHPSADPEGTECSADRAVPASTTEGQVLQQPPCFLEDEEEELYISESMQEI TDAPPTIQVPHEDLCVEPGQPVTFTAIITGRPAPKIEWYKDEEELLANENVKLAQHGARC SVTIVCPEGEDSGIYTCFAYNDSGHESCQAQLTVEEGPLEHREREVELGKRRKLFSVYDV HDEIGRGTFGVVKRVVHRRTGEVFAAKFLPVRSSTRTRAFQERDLLSRLAHPRVACLLDF FCTRRTLVLITEMCCSHGLLDHLLLKGSVSEREVRSFIQQILEGLGHIHSMNILHLDMKP DNILMVYPPRDEIKICDFGFCQEIDTSRHQYSMLGTPEFVAPEIVHLEPVTVATDIWSVG VISYICLVCRCPFVGETDRATLLRVGEGTLNWDAPDVTCRSPEAQNFLHILLQPDPEKRP SAFESLSHEWFQDELAGEDTDEINTRNLKAFISKRKWQRSLTCIGSVLTLRPIPELLDAP LRETAATVPREPQEHSSSSLSSGSSSEYDEADSWDFFQHYSQTEEEEETEDDYDPLMERA RIPEPFPRHHLDTEEEEVTLGDEEDGDVERRSVLERSMSRQSAASSETSCQRTPQRERRL SKDSSPSLHLSDGDEGSGSEGGRIPRGSVIRSTFYSTSHQLSPMSARHMTLRDKFQAKKQ ERGRKPIRRSLSGRLSEPLIEYVEDETDAARGQRRVSVQPAMQKSCSFDSGVGLVHGNVP PHRRSRSLDGFSRLSPGSPICSKSGEEEGSQSLKEDFTDDEGTARNLLSIPQRPTRRRGS VAPVRGIPLQVGSALPSRLLAGDRALSKLDQEPTQGGAFTGSQGSLAESFHLEHGGSDSS SRLGSYEELSHGHRRGRSRSGYSEGYNDQGEPLISSSPFSFTEVKSVSSFPQAPPRNRTR SNPNLTTYQRGQLGTPLTASPSPSLSSLQAPERPPRAKDKKDLRGLQRHASAPALELQPP VGKSPKLGFLNIFRRQSWTGQPYSQLENPEFGPTLGEIMSPDTPTMSLRKRMRASASSLT KLFSKSSSKEDVSKGPIVKVSPEVGGFTGPESPKKRTTKLLPSFKMPVFKRTKGLLVRPS KPEVLQLDGGGVLLVWKPVHSSDPVTYCVQYCTDATGGDWTLLSEEVADSCYVVKDLPRG ASYVFRVSCITKTGAGPFSDASVPVVMATHPEETHIPLIQTESPGSKVIGLDQQTHQKTY SFLSEINRGRFSIITMCRDVETSQVFAAKVTPYKAEQRQLVLREYQLLKKLHHPHLVQLH TAYLTSSYLVLVEELCPGKELLHSLAARELYSETHVAELLVQILSAVDYLHGRRVIHLDL KSDNMLVDDCNHLKIVDLGSAQLFTPGQPLNIEHIQGLSESRDGLSKVYIVLPKAPEILE GHGVGPETDIWAVGVLSFIMLSADSPFHAELDSEQDRNIKKGKIQFGRCYPGLSEGALNF MKSSMNNKSWGRPTAAECLHSPWLRAHRASHRGRQSKVCFSTDKLKEFLTQKEEKRDQVR TKLQGPFFQ NT seq 18930 nt NT seq  +upstreamnt  +downstreamnt atgggcgacagcaaacatccagggaaagttgctgctgcaaagaatcacctgcaggtggta aagggactggaggacgcggaggtgtctgagtgtgagagctgctccttcgaggtgacgctc agcgtggcctacatcgccggcgtgtggaccagagacgggacgcagctgaggtcaaagccc agctgttgcatcagcacacacgggaagaaacactccctcatcctgaaaagggtaaccctg ggagacgcaggcttgtactgctttcaggctgacggccttcagacctcgggcagactcggc gtcagagctcgagacatctacatcgtgaaggagctggaggatgtggacacgagggaacgc cagactgtgaactttctctgcgaggtcaaccaggtcgatgtggatggtcggtggtacaga gacgactgccggattcgaccgggggacaaaatcaagatcagacaccagggtagaacacac acgctgtgtttcaaatcggtccggccagaacatgccggggagatcaggttcacggcagag cgcgtctcttcctacgctactctcacggtcaaagagctgccggtccaaatagtgcgacct ctgagggtcaagatcgccatgtatcgccaccgagggctcctggagtgccaggtgtcacgg cccaatgcgcaggtcaagtggtacaagaacaggaaggagctccttcccagtaagaagtac caggtaatcaaccaggacgtctacaggcagctgtacatcgatgacgtctgctcatcagat gaggacacctacacctgtgatgcaggagacgaccaaacgtcttgtcagcttctcgtggag gagcaggctatcagcatagtgcgaggaatgagctctgtggaggtgatggagccggagcca gcactgttccaggtggagaccagcctaaaatcaggaagaccacccagatggaccctgaat ggagaggtcctagagcccagtgctgcggtgaacatcaacaggaagggcaccgtccacagc ctctgtctgacctccactgagagctccatgtgcggccctgtggtctttgtggctggaaag agtcgttccactgctcaactgactgtaaaggagagacccctgcaggtgtcccaccctttg gaagatactgacgcgaaggagaacagctctgccaccctgagctgcgggtttatgccctct cccagggtggtgcggtggtttaaaggccgcacggcgctgaaaacctcaaacaagtacagc atgaagagggaaggacaccgagccgagctgaccattcacggcctgacagggatggattca ggacaataccgctgtgttgctggcggttcacagagcaccgcacaggttaaggtggaagtg cgaacactgaagctggttaagcaccttgagccagtggaggtggaggaggacggctgcgcc accttctcatgcgagctgaacttcgtggtcgccaacgctgagtggctcctcaacaacgtc cgcctctattccaacgccatcaacaggatccagcacatgggcaccatgcacagcctcaca atcaagaagctgcgtccacaagtgggcagggtcaccttcaaagcaggtctcctgtctgag agcgccttgttaaaggtcaaagagcgaccggctgtgttcctgaagtctctggaggacgct gtaggagaagaacaaggggatgtttgtctgcactgtgaaatctccaaggagacagcgacc cctgtatggaggaaagatggtttcgtgttgacccctgatgataaacatgagcttctgcag tttggcaaaaccctggcactgatcatccactccctgagcaaagacgacgcgggacagtac acgtgcgacctcggcaccagtcagaccaaggctaaagtcactgtccacgacttacacatc acgatagtgcagcgtctgaagactgtgtcggtcctggaaggggagaattgcacgttcgat tgccacctctcccacgatgttgacgatcagccccgctggacgataaacggccaggtcgtg gataccgacggccacgtccaggtggtcaacaacggccgcaggtacaggctggctataaag gatgcactgctgagcgacgctggagacatcgtcttcacaataaaagacctcacatgtagg accatgctttttgttaaagaaaaacccgttcacatcttcagagatctacttaacgtcaag gcagtgccgggcgaggacgctgagctgagctgtgagatcaccaagacggacgtcaccatt cggtggctgaaaaatggccatttgatccggcagagcccaaagtatgagatgagtgttgcg aagaaccaggcgaagctggtgatcaggaacgcaacgatcagggactctggagattactgc tgcgaggcagatggcgtcgcttcacgggccaaagtggagatcagagaactccagcatacc ttcgcgatggagctgaaggactcacgggccgaagaaaaggccaaagtgaccctggagtgc gagaccaggcgtccagccaagcgggtgaaatggctgaagggcatgttggaactgaggtcc agcaggaagtatgtcatcagacagaagggagtgatgctgtcgctgacaatcaacagcctg gagaaatccgacaccgacatttacatatgtgatgttggcaccatgcaaagccgagcgcag ctgaccgtgcagggtcagacggtgttcatcctggatgagttagaggatgtcgagtgtctc gagggtgacacggtcacgttccggtgtagaatctgccccagcgactacagcgatgtcaaa tggtatctggacgagactctgttatacaccaatgaactcaatgagatccagttgttggct ggagggtaccatgtcctgacgttcaggcagcttgcccgcaaagacaccggcactatttca ttttctgcaggggataaaagatcatacgcctcgctgctcgtcagagagaggcgtcccacc atcattaaagcgctggaagactgtgaggccatcgaaggaggtggcttgattttgtcttgc ctgacctccaaaccgtgtcacatccgatggtacaaagatggctgcctgatgtggaactcc tcgaggtatttcaccagtcggtctggctgtgaggcccggctgacaatccgggaggttggc cgcaacgatggcggagtctatgagtgcagcgccggctcagtttcaaccagggctgtggta actgtcaaagccatcccagcagagttcacacagcctctgaagagtgtggaggccagggag ggagaaactttaactctgacctgcgaatactctctgcctggcatccatttcctctggaat aaaggttatgagagcatcaggcccggagataaatacttaatgaaacagaggaagactgtc atctctctgaccattcaaaaccttcatcccgaagactcaggggaatacacctgtcagtgc agagatcaccgcactacagccagcctcaaagttcatgctatccccaccacattcacacag cagctgaggaatattcaagcgcaggagggaagcaacgttgtcctccgctgtgagctgtcc aaacctggaattccagtagaatggaggaaaggagacgagccgttaaagaatggggtcagg ttccagataaggcgaagagagaccaccttagagctccttatatggaagccagtgcccgag gacagcggagtgtacagctgcgtgtgcgccgaccagaagacgtcagccaatgtcaaaatc accgccctcccagtcaccttcaagcagaagctgaagaacgtgcagatcgaggaaggcaac gtcgcggttttccgctgtgagctgtcaaaagtgggccacagcgtggaatggatgaagaga ggcgatgaggtcatcagaggtggagagaagtatcagatgcggcagagagacactctgttg gagctgcggatcttggatgcaaaacctgatgacagcaatatttacacatgcgtctgtgga accgtagagaccactgcaactctgactgttaacgctcttcctgtcaccttcaaacagaag ctaaaaaatgtacaagtggaggaaggcaacaatatcacgctgtactgtgagatctccaag cctggcatcccggtggaatggagacgtgctggagatcttttagaaaatggggacaagtac cacattaggcagagggagacgaccctggagttgaccatccgagacgtcgatccggaggac agcggcgtctacacctgcgcgtgtcgggatcagcggacaaaggctactgttaaagttgtt gctgttccagctacatttaaagtgagcctgaagagtcaggacgctgaggaagggagcagc gtcagcctgagctgcgagctgtcgaagaaaggggtgctagtgcagtggaagagagatgcc caggtgctgtctgaagggatgtgcccaggaaagtatcagatgaaggtggaagggaagacg gctcagctgaccgtccacagtgtccaggcagaggacgcagggaggtacagctgtatcgcc ggagacgagaaaacctcagctgaagtcagagtgaaggcactccctgtgacatttaaacga ggagtccagaacatagcggtgaaggaaggggacagcggggttctctgtggcgagctctcc agacccggagctcaggcggaatggaggaaaggacgagtcgtcctgacaccaggagagaag tttgagatgaagcaggaaggctgttttgtaaagctgttgatcaactgtgtggaggagagt gatgctgggaaatacacctgcaagaccaatgacagccaatcaaccgctgagctcactgtt catggcttaccaccgactttcagacggcctctcatcaaccaggaagtgatggagggcaac agcgtgattctgcactgtgagctcagcaaagctgcttcttcggtggagtggaggagagga ggagagctgctaaagcatggagacaaatatcaggtgaggaaaaaagagctgcaggtggag atgaagatcctcgacctcagtgtcagcgacggcggagagtacagctgtgtgtgtggagaa caggcaacgagagccgtgatcactgtaaaagagtggcccatcagattcctccaagagctg aaaaacattcaggtgcaggaaggcaacgaagtcaaacttcgctgtgagatctcaaaagca ggcgcttcaatagagtggaagaaaggagagaaagtgttgagcgacggagagaaataccgg atgaaacagagtggctccatgctggagcttgtcattaggaagagccagcctgaggacagc ggcacatacagctgtgtttgtgctgaagtcaaatcttctgccaccatcatcatcactgca atcccaatcactttcaagcaaaagttgaagaaccaggaagttgtggaggagggttctgtg acgctccgctgcgagctttctaaagccggagttccggtggagtggaggaaagaggctcag ctcctccaggagggagaaaaatatcagatgagacaagagggtagagcggcagagatgtcg ataaggggagtgactcttgcggatggtggggagtacagctgttctgttggtacagctgtc acggcggctgagattaaagtgagagcattacctataaccttcaaacaagagatggagaac ttggtagtgaaggagggagatagtgctgttttcaactgtgagctctccaaacccggagcc ccagtggactggaggaaaggaagagtcgtccttaaacctgggtacaaatatgagatgaag ctagaaggccgtctcagtcaactgacaatcaacaacatagaggagagcgatgctgggaag tatacctgtaagaccagtgacagccaatcgacagctgagctcactgtcagagctcctccc atcatgttcaagacaaagttaaggagccagcaggtggaggaggagaagagtgtgacactg agctgtgagctgtccaagcctggccttgctgcgcagtggaggaaaggacaagagcagctt cagaacaacttcaagtatcaaattaggaatcgaaacagcatcatggagctgaccatcaaa aacacacagttggtggacagtggactttacagctgcaactatggtgacgttaaaacctca gccaacatcacagtaacaccaatccccctctctttcaagacgggtctgaagaaccaggag gctccagagggcggcaacgtgtccctgcgctgtgagctatccaggaccggcgtgcctgtg cagtggtttaagtctgaaaatgagctctgtcaaggaggtcgctatcagatgacactcgga gggaatatagccgagatgcacatcagaaacatccagcccgaggatgtcggagagtacagc tgcatctttggggagcaaaagacaacggctgaagtaaacgtcagagcggcagcatccgtg tactttgagaaggagctggagagccaagctgtgatggaaggaaaacccgtgcttctctct tgtgaagtttccagtgctaatgtccctgtgacttggaagaaggacaacattgtgttagag gatggaggacgctacattttaaagaaggaaggcaccagacactccttagagatcaggaaa ctgcaactggaggatgctggagagttctgctgtatcagcagaggcaagaagaccactgct aagctggttgtgagagagcgcgtgcggattcttacagcgctacaggatatcactgtgaca gcgggccaagatgccacgtttgtatgtgagctgactcacgcagaggccgagggggtctgg tggctcggctctagccccttacagaggaacgaaatgaaccagatgatgtgccagggtcgt cagcatcggctggtcctcgccatgacgacacccgaggagacgggcactgtggcatttgtg gttggggaggagaggacatcagcccatcttctggttgttccaaagcccaaagttttattt gaggagaagcccagagatgttgtcatcatggaaggagagacagcaattttgtcctgtgtg accactgatctcacctctccggttacttggaaatgcaatcatgtccccctgcgaaatggt gataaatatgagacgcgcaaggagggaaaagtcaaccttctacttatccatgatgcagat cctgaaaatgctggtatctactcctgtgatactggggatgtccagagcagtgccaggctt accgtgacagagcgtccgccgttcttccaagaaggcctgcagagtgtggaggtggaggag ggcgggtccgtctttctgtgctgcgaactgtccaaacttggagtgccgattcactggaaa aaggacagacttcctctgagatcgagcagaaagcatgaaataaaagaggatggctgtttc ctccagcttcacgtctgggatctgaaacctgaagacagcggcagctactcatgtcaagca ggaaatgcagagaccacagcgaccgtgacggtgaaagagctccctccattcttcaagaaa gaattaagaaatttgggggtcgaggagggcagctcggcctctctgtgctgtgagctgtcc aaacccggagtggcagtgcagtggaagaggaacaggataccgctgagagccggcaggaag tacgagatgaagcaggagggctgcctcctccagctgcagatccgtgatctcatacctgag gacagcggcagctactcatgtcacacagaaagtgcagagacaagtgcatcattgtctgta aaagaactcccgccaattttcacagaatgtttgcagaatgtgacggctaatgagggaggc acactggccttgagatgtgagttgtctaagcctggagtggctgtgcaatggaagaagaac aaggtggtgctgagatccagcaggaagtatgacatgaagcacggcggctgtctgcaccag ctcaacatcggggaactcactcttgaggacaacggcagctactcctgtcatgcaggaagt gcagagacagctgcagtagtgtcagtgaaagcgttaccaccatttttcaaagagggtttg cagagtgtgaaggtggaggaaggaggagctgcctccctttcctgtgtgttgtccaagcct ggcgtatcagtacagtggaagaagaacaagctggtgctgagatccagcaggaagtatgaa 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gaagacagtggagtctacacatgccagacaggaagtgcagagacctctgcaactgtgtct gtgaaagagatccagccgcctccagcaaaggaagagcctccagtgatcgtctctcagact gtagccaaacctctcaaagcatctactcctgcagaaaatgtgagacctgttcctccagag cccaaaaagagatccaacaggaaagcatcaataacaagtctggaaaaagatgcaattttg actttggacaaaaatcagtctgtggtgaaggacaggaaagaagagctaaagggaacacct gcaaggtctgaggagaaagacttgggcgttctaaagaatggaacacgggcagaggaattt aatctggagaaagatgaagccaagaatttcgataagtttacaaaactaactgatattaaa aaggaattggtgggtgaggcaaagaagaaaagagagaaagatgtttttattgaagcagaa caaccagcaaccatcttagagaaattggtcctggctgagcagccagaggtggtgttggaa caaaagagacggtcatttgtatgtctgcaaaatgaagatgaaggtgaagtgatcccaaaa caaccagcaaagccttcagagaaggaaaataaagtggacacaaagagaccgagtccagct ttccaagaagaaatgcctggaaaagaagatcaagatgatgtaagaggccctttgaagcaa caagaagcaagatcagccgtacaaaaagaaggtgacaaaacagaggagtcttttaaacca ccagtgagatcaagagggaggttaacattagagaatcaacaacccaacatggatcttttc cagccagaaaaagctttagaggtttccgaagaaggccttgaacagagaaaccaggtgaaa caaggattgtcaaccacagtttcccaaaaggagaaaacaggacaaaagtcacaagaaaaa 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actctggctaaggtggtggtgcaggctcctcccagatttgtgtcccgactggagagtgct tgtctcattgagggcgaagacatccagttttcctgttccacactcactactcctttaccc cggatcaggtggtccaaagagggtcgagagttgttcaacggggaaaagtattgcatccta aatgatgctcggagtgggatcctgagtctgacggtcatcggtgcaacagaggctgatatt ggacaatacgagtgtgagctctggaacgagtttggctgcgtccgatgcaaggccgggctt tgtcctgcttacgtacctccaactgacgtggagagcgaccaccctcaggacttacctgct aaagatgcagattcagacagctggaccactgccttcgtcaacaagtggttgcaaagtgac ttcaacccagctcctgctgccaagatgctccacccctctgcagaccctgaaggaactgaa tgtagtgccgatcgggctgttcctgcgtcgaccacagaaggtcaggtgctgcagcagcct ccgtgtttcctggaggacgaagaggaagagctctacatctcagaatccatgcaggagatt acagatgcccctcccaccatccaggtgccccacgaggacctgtgtgtagaaccgggccag ccggttacgttcactgccatcatcacggggagacctgcaccaaaaattgagtggtacaag gatgaagaggagctgctagctaatgagaatgtaaagctagcgcagcatggcgcccgttgc tctgtgaccatagtgtgccccgagggtgaggacagcggaatatacacttgctttgcctac aacgactctggtcacgagtcctgccaggcccagctgacggtcgaggaaggccctctggag caccgggagagagaggtggagcttggaaagaggaggaagttgttctctgtttatgacgtc catgatgaaattggaaggggcaccttcggggtagtgaagcgcgtcgttcacaggaggaca ggtgaggtgtttgccgccaagtttctacccgtgcggagcagtacgcggaccagagccttc caggagagggacttgctgtcccgcctggcccaccccagagtcgcctgtctgctggacttc ttttgcaccagacgcactctggtgttgatcacagaaatgtgctgttcccatggacttctg gaccatctccttcttaaaggctcagtttctgagagagaggtccggtcgttcatccagcag atcctggaaggcctcggtcacattcacagcatgaacattttgcacctggatatgaaacct gataatatcctgatggtgtatccaccgagagatgagatcaagatctgcgactttggcttc tgccaagaaatagacacgtccaggcaccagtacagcatgctgggaacgccggagtttgtt gccccagagattgttcaccttgagcccgtcactgtggccaccgacatttggtctgtcggg gttatatcctacatatgtcttgtgtgccgctgccccttcgtgggtgagacagaccgagcc acactgctcagagttggggaaggaaccctgaactgggacgcccccgatgtcacctgtagg agcccagaggcccagaactttcttcacatcctcctccagccagatccagagaaacggcca tctgcctttgagtccttgagccacgaatggttccaggatgaacttgctggagaagacact gatgaaatcaacacaaggaatttaaaagcatttatctccaaaaggaaatggcagcgctcg ttgacttgcatcgggtcagttctcactctcaggcccatcccagagctgctggatgctcct ctcagggaaaccgctgctaccgttccccgtgagcctcaggaacacagcagcagctctctg agcagcggctcgtcgtccgagtacgacgaagccgactcctgggacttcttccagcactac agccagactgaggaggaggaggaaaccgaggacgactacgatcctctgatggagagagcg cggatccccgaaccattccccagacaccatttagacacagaggaggaggaggtcacattg ggagatgaagaggatggagatgttgagaggaggagtgtgctggagcggagtatgagcagg cagtcagctgcgtcatcagagacgtcctgccaaaggacacctcagagggaacgtaggctc agcaaagacagcagcccctccctccacctctctgatggagatgagggttcggggagcgag gggggccgcatcccacgtggaagcgtcatcagaagcactttctacagcacctcgcaccag ctgtcccccatgtctgccagacacatgactttgcgggataaatttcaagccaaaaagcag gagaggggccgcaaaccaatacggagaagcctttccgggcggcttagcgagcccctgatc gaatacgtggaggatgagacggatgccgcccgcggccagaggcgagtgtccgtccaaccc gcgatgcagaagtcctgctcgttcgacagtggcgtcggcctcgtccacggcaatgtccca cctcacaggaggagcaggtctcttgacgggttctctcggctgtctcccggctcacccatc tgctccaagtcaggtgaggaagagggttcccagagcctgaaggaggatttcacagatgac gaagggacggcaagaaacctgttgtccatccctcaacgacccacaagaaggaggggctcc gtagctccagtgcgggggattcctctgcaggtgggatcagctcttccctctcgcctcctc gctggagatagagcactctctaaactagatcaggagccgacacaaggaggcgcctttaca 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gcctcttacgtgttccgggtgagctgcatcaccaaaacaggcgccggacctttcagtgac gcttctgtgccggtcgtcatggcaacacaccctgaagagactcacattcctctaatccag actgaatcaccggggtcaaaggttatcggattggatcagcagacacaccagaagacctac agtttcctctcggagattaacagggggcgtttcagcatcatcaccatgtgcagggacgtt gagaccagtcaggtttttgctgccaaggtcaccccttacaaggccgagcagaggcagctg gtgctgagggaatatcagctcctgaagaagcttcatcacccccacctggtgcagctgcac accgcctacctcaccagcagctacctggtgttagtggaggagctctgccccggcaaggag ctgctccacagtctggcagcgagagagctctattcagagactcatgttgcagagctgctg gttcagattctgagcgccgtggactacctccacggacgccgcgtgatccacctggacctg aagtccgacaacatgctggtggacgactgcaaccacctgaagatagtggacttgggctcg gctcagctcttcacgccgggccagcctctgaacatcgagcacatccagggcctgtcggag agcagagacggcctcagcaaagtttatattgtccttcccaaagctccggaaatcctcgaa ggtcacggcgtcggccctgaaactgacatttgggccgttggagtgctgtcgtttatcatg ctgagcgccgacagcccgttccacgcggagctcgactcggagcaggaccgaaacatcaag aaagggaagatccagtttgggcgctgttaccccggcctgtcggagggagccctgaacttc atgaagagcagcatgaataacaaatcctgggggaggcccacggcagcggagtgtctgcac 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