Thermus thermophilus HB27: TT_C1223
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Entry
TT_C1223 CDS
T00170
Name
(GenBank) D-alanine-D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tth
Thermus thermophilus HB27
Pathway
tth00470
D-Amino acid metabolism
tth00550
Peptidoglycan biosynthesis
tth01100
Metabolic pathways
tth01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tth00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TT_C1223
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TT_C1223
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TT_C1223
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tth01011
]
TT_C1223
Enzymes [BR:
tth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TT_C1223
Peptidoglycan biosynthesis and degradation proteins [BR:
tth01011
]
Precursor biosynthesis
Amino acid ligase
TT_C1223
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AAS81565
UniProt:
Q72IA9
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All DBs
Position
complement(1186711..1187670)
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AA seq
319 aa
AA seq
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MRVLLIAGGVSPEHEVSLLSAEGVLRHMPFPTDLAVIARDGRWLLGEKALAALEAKAAPE
GEHPFPPPLPWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSK
RVLAQAGVPVVPWVAVRKGEPSMVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAF
RYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPA
PLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGEVYLNELNTIPGFTPTSMYPRLFE
AGGVAYPELLRRLVELALT
NT seq
960 nt
NT seq
+upstream
nt +downstream
nt
atgagggttcttctgatcgccgggggcgtaagccccgagcacgaggtctccctcctctcc
gcggaaggggttctgcgccacatgcccttccccacggacctcgccgtgatcgcccgggac
gggcgctggcttctgggggaaaaggccttggccgccttggaggccaaggcggcgcccgag
ggggagcatcccttccccccgcccctcccctgggagcggtacgatgtggtctttcccttg
ctccacggccgcttcggcgaggacgggacggtccagggctttctggagcttttgggcaag
ccctacgtgggggcgggggtggcggcgagcgccctctgcatggacaaggacctgagcaag
cgggtcctcgcccaggcgggggtgcccgtggtcccctgggtggcggtgcggaagggcgag
ccctccatggtgccctttgacccccccttcttcgtcaagccggccaacaccggctccagc
gtggggataagccgggtggaacgctttcaggaccttgaggccgccctggccttggccttc
cgctacgacgagaaagcggtggtggagaaggccctctccccggtgcgggagctggaggtg
ggggtcttgggcaacgtcttcggcgaggcgagccccgtgggcgaggtgcgctacgaggcg
cccttctacgactacgaaaccaagtacaccccgggccgggccgagctcctcatccccgcg
cccttggaccccggcacccaggagaccgtccaggagctcgccctcaaggcctacaaggtg
ctcggggtgcgggggatggcccgggtggacttcttcctcgcggagggggaggtttacctg
aacgagctcaacaccatccccggcttcacccccacgagcatgtacccccgcctctttgag
gcggggggggtggcctacccggagcttctcaggcgcctggtggagctcgccctcacctaa
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