Thermus thermophilus HB8: TTHA1587
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Entry
TTHA1587 CDS
T00220
Symbol
TTHA1587
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00470
D-Amino acid metabolism
ttj00550
Peptidoglycan biosynthesis
ttj01100
Metabolic pathways
ttj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TTHA1587 (TTHA1587)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TTHA1587 (TTHA1587)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TTHA1587 (TTHA1587)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
ttj01011
]
TTHA1587 (TTHA1587)
Enzymes [BR:
ttj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TTHA1587 (TTHA1587)
Peptidoglycan biosynthesis and degradation proteins [BR:
ttj01011
]
Precursor biosynthesis
Amino acid ligase
TTHA1587 (TTHA1587)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
BAD71410
UniProt:
Q5SHZ3
Structure
PDB
LinkDB
All DBs
Position
1:complement(1510700..1511659)
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AA seq
319 aa
AA seq
DB search
MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPE
GEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSK
RVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAF
RYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPA
PLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFE
AGGVAYPELLRRLVELALT
NT seq
960 nt
NT seq
+upstream
nt +downstream
nt
atgagggttcttctgatcgccgggggcgtaagccccgagcacgaggtctccctcctttcc
gcggaaggggttctgcgccacatccccttccccacggacctcgccgtgatcgcccaggac
gggcgctggcttctgggggaaaaggccttgaccgccttggaggccaaggcggcccccgag
ggggagcaccccttccccccgcccctctcctgggagcggtacgatgtggtctttcccttg
ctccacggccgcttcggcgaggacgggacggtccaggggtttctggagcttttgggcaag
ccctacgtgggggcgggggtggcggcgagcgccctctgcatggacaaggacctgagcaag
cgggtcctcgcccaggcgggggtgcccgtggtcccctgggtggcggtgcggaagggcgag
ccccccgtggtgccctttgacccccccttcttcgtcaagccggccaacaccggctccagc
gtggggataagccgggtggagcgcttccaggacctggaggccgccctggccttggccttc
cgctacgacgagaaagcggtggtggagaaggccctctccccggtgcgggagctggaggtg
ggggtcttgggcaacgtcttcggggaggcgagccccgtgggggaggtgcgctacgaggcg
cccttctacgactacgagaccaagtacaccccgggccgggccgagctcctcatccccgcg
cccttggaccccggcacccaggagaccgttcaggagctcgccctcaaggcctacaaggtg
ctcggggtgcgggggatggcccgggtggacttcttcctcgcggagggggagctttacctg
aacgagctcaacaccatccccggcttcacccccaccagcatgtacccccgcctctttgag
gcggggggggtggcctacccggagcttctcaggcgcctggtggagctcgccctcacctaa
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