Thermoanaerobacterium thermosaccharolyticum DSM 571: Tthe_0017
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Entry
Tthe_0017 CDS
T01299
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
ttm
Thermoanaerobacterium thermosaccharolyticum DSM 571
Pathway
ttm00290
Valine, leucine and isoleucine biosynthesis
ttm00660
C5-Branched dibasic acid metabolism
ttm01100
Metabolic pathways
ttm01110
Biosynthesis of secondary metabolites
ttm01210
2-Oxocarboxylic acid metabolism
ttm01230
Biosynthesis of amino acids
Module
ttm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ttm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Tthe_0017
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tthe_0017
Enzymes [BR:
ttm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
Tthe_0017
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Motif
Pfam:
Iso_dh
DUF6259
ERp29
Motif
Other DBs
NCBI-ProteinID:
ADL67615
UniProt:
D9TMD8
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Position
17087..18154
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AA seq
355 aa
AA seq
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MYKIAVLPGDGIGKEVIEEALKVLDSVSEKYGIEFDIKKYLFGGCAIDEYGTPYPKETEE
ACLESDAILLGAVGGPKWDDLDGDKRPEAGLLALRKSLDVYANLRPAILFSSLKSASPLK
DELLKDGLDVLVVRELTGGIYFGERGTEKIDYGYKAYDTEAYTTKEIERIAHIAFKAARN
RKKKVTSVDKANILDSSRLWRKVVNEVSKEYPDVELNHQYIDNCSMQLIKDPSQFDVILT
SNLFGDILSDEASQLTGSIGMLPSASLRGDKVGLYEPVHGSAPDIAGTKKANPLATILSV
AMMLEYSFDRLDAANDIRKAVNELLEDGYRTPDLGSGIILNTEEMGDMVVKYLKR
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
atgtacaaaatagctgtattgcctggtgatggaataggaaaagaagttatagaggaagca
ttaaaagtattggattcagtttcagaaaagtatgggatagagttcgatataaaaaagtat
ttgtttggcgggtgtgcaattgatgagtatggtactccatatcctaaagagacggaagaa
gcgtgtcttgaaagcgatgctattctactaggtgctgttggtggtccgaaatgggatgat
ttagatggagacaaaaggccggaggcagggcttcttgcattaagaaaaagcctagatgtg
tacgcaaatttaaggcctgccatcctttttagctccttgaaaagtgcatcgccacttaaa
gatgagcttttaaaggatggtttagatgtgcttgttgttagagaactgacaggtggtata
tatttcggtgaaagaggaacggaaaagatagattatggttataaagcgtatgatacagaa
gcttataccacaaaagaaatagaaagaatagctcatattgcttttaaagctgctagaaat
agaaagaagaaagttacatctgttgataaagcgaacatattggattcatcaagactatgg
agaaaagttgtcaatgaagttagcaaggaatacccagatgtagaattaaaccatcagtat
attgacaattgctcgatgcagcttataaaagatccgtcccaatttgacgtaatattgaca
tccaatttgtttggcgacattttatcagatgaagcatcacagcttacaggatctatagga
atgctgccatctgcaagtttgagaggagataaagtcggattatatgagcctgttcacggt
tcagcgccagacattgcaggtactaaaaaggccaatccattggcgactatattatcagtt
gcaatgatgctggaatattcatttgataggcttgacgccgcaaatgatataagaaaggct
gtaaatgagctgttagaagatggatatagaacacctgatttaggaagtggcattatttta
aatactgaagagatgggagacatggttgttaagtatttaaagaggtga
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