Tropheryma whipplei TW08/27: TW257
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Entry
TW257 CDS
T00117
Symbol
ddlA
Name
(GenBank) D-alanine--D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tws
Tropheryma whipplei TW08/27
Pathway
tws00470
D-Amino acid metabolism
tws00550
Peptidoglycan biosynthesis
tws01100
Metabolic pathways
tws01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tws00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TW257 (ddlA)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TW257 (ddlA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TW257 (ddlA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tws01011
]
TW257 (ddlA)
Enzymes [BR:
tws01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TW257 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:
tws01011
]
Precursor biosynthesis
Amino acid ligase
TW257 (ddlA)
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Paralog
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GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp_3
ATPgrasp_TupA
Motif
Other DBs
NCBI-ProteinID:
CAD66933
UniProt:
Q83I36
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All DBs
Position
286979..288022
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AA seq
347 aa
AA seq
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MRSLLLLFGGRSQEHSVSYASARALLEHICDEWTVIPVGITKHGDFVYCSTVSEQDYGEV
IDNGNRVVWPSRAGCKKIEVVQARGKSFFVEFDLVFPLLHGVFGEDGTIQGMLDLLDIPY
VGSGVFASAAAMDKHYTKILCSHAGIPVLPWYLIKGHAWHKNRDSFLKQISDRFTFPLFV
KPVDAGSSFGCTFVDFFEQLPVAIEHALQHGKSAIVEPALDAPEVFCSLIENNGVLQCSE
LVFVKHSGSKFYDYSAKYLNPVEFVIPAQFDNTDGYAEIASKVFFELGCRHYARIDFFVT
ESGLVLNEINTSPGLTQKSIFPSSFKSMQYSQVIETILASAYCQVKR
NT seq
1044 nt
NT seq
+upstream
nt +downstream
nt
atgcgcagcttgctcttattatttggtggtcgctcacaagagcattcggttagttatgca
tcggccagggcgttgcttgaacatatatgcgatgaatggactgtaattcctgttggcata
acaaaacacggcgattttgtatactgcagcactgtgtcagagcaggattatggcgaagtc
attgataatggtaatagagttgtttggcccagccgcgcggggtgcaaaaaaattgaggta
gtccaggctcgcggcaaaagcttttttgttgagttcgatctcgtatttcctctccttcat
ggggtgtttggtgaagacggaacaatccaggggatgcttgacctgcttgatattccttat
gttggttccggagtatttgcaagtgcagctgcgatggataagcactatacaaaaatactg
tgttcccacgcgggcattccggttctgccgtggtatctcattaaggggcatgcttggcat
aagaacagagattcttttttgaagcaaatttctgacagatttacctttcctctgtttgtg
aagcctgttgatgctggctcgagttttggttgcacttttgttgattttttcgagcaattg
ccagtggctatagaacatgctcttcaacacggaaaatctgctattgttgagcctgccctt
gatgctccagaagttttttgctcactcattgaaaataatggggtattgcagtgctctgaa
ctcgtttttgtaaaacatagtggcagtaagttttatgattattccgccaaatacctgaac
ccggttgagtttgtgattccagctcagtttgacaataccgacggatatgccgagattgct
tcaaaagtttttttcgagcttggctgtcgccactacgctcggattgatttttttgttaca
gaatcgggtcttgttctaaatgagattaacacatcacccggcctcactcagaaatcgatt
tttccatcaagctttaagtcgatgcaatacagtcaagttatagagactattcttgcctca
gcctactgccaggtcaaacgctaa
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