Ursus arctos horribilis (North American brown bear): 113241916
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Entry
113241916 CDS
T05909
Symbol
PLA2G4D
Name
(RefSeq) cytosolic phospholipase A2 delta
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00564
Glycerophospholipid metabolism
uah00565
Ether lipid metabolism
uah00590
Arachidonic acid metabolism
uah00591
Linoleic acid metabolism
uah00592
alpha-Linolenic acid metabolism
uah01100
Metabolic pathways
uah04010
MAPK signaling pathway
uah04014
Ras signaling pathway
uah04072
Phospholipase D signaling pathway
uah04217
Necroptosis
uah04270
Vascular smooth muscle contraction
uah04370
VEGF signaling pathway
uah04611
Platelet activation
uah04664
Fc epsilon RI signaling pathway
uah04666
Fc gamma R-mediated phagocytosis
uah04724
Glutamatergic synapse
uah04726
Serotonergic synapse
uah04730
Long-term depression
uah04750
Inflammatory mediator regulation of TRP channels
uah04912
GnRH signaling pathway
uah04913
Ovarian steroidogenesis
uah04921
Oxytocin signaling pathway
uah05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
113241916 (PLA2G4D)
00565 Ether lipid metabolism
113241916 (PLA2G4D)
00590 Arachidonic acid metabolism
113241916 (PLA2G4D)
00591 Linoleic acid metabolism
113241916 (PLA2G4D)
00592 alpha-Linolenic acid metabolism
113241916 (PLA2G4D)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113241916 (PLA2G4D)
04014 Ras signaling pathway
113241916 (PLA2G4D)
04370 VEGF signaling pathway
113241916 (PLA2G4D)
04072 Phospholipase D signaling pathway
113241916 (PLA2G4D)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
113241916 (PLA2G4D)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113241916 (PLA2G4D)
04664 Fc epsilon RI signaling pathway
113241916 (PLA2G4D)
04666 Fc gamma R-mediated phagocytosis
113241916 (PLA2G4D)
09152 Endocrine system
04912 GnRH signaling pathway
113241916 (PLA2G4D)
04913 Ovarian steroidogenesis
113241916 (PLA2G4D)
04921 Oxytocin signaling pathway
113241916 (PLA2G4D)
09153 Circulatory system
04270 Vascular smooth muscle contraction
113241916 (PLA2G4D)
09156 Nervous system
04724 Glutamatergic synapse
113241916 (PLA2G4D)
04726 Serotonergic synapse
113241916 (PLA2G4D)
04730 Long-term depression
113241916 (PLA2G4D)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
113241916 (PLA2G4D)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
113241916 (PLA2G4D)
Enzymes [BR:
uah01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
113241916 (PLA2G4D)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
113241916
NCBI-ProteinID:
XP_026335594
LinkDB
All DBs
Position
Unknown
AA seq
817 aa
AA seq
DB search
MERLTTRGPPGRPHQGEASACWRLTVRVLEARNLGWTDLLSEADPYVTLQLPTVPGTKFK
TKTITNSSHPVWNETFSFLIQSQVKNVLELNVYDEDSVTEDDACFKFLYDVSEVLPGKLL
RKTFSLQPQGQEELDVEFLLEKTSDCPENLITNNVLVARELSCLDVHLDHTESVATVTDQ
AKLELELVLTGSYENTQTSALGPASAFRFHYMAAQDAELSARVRSSESNGWNSDKTAGHL
TVPLRSLAMGKEVTINIPATNTPGVRLQLETESCPKKLAVHLGFDLCAEEQAFLSRRKQV
VAKALKQALQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGI
SGSTWTMAHLYGDPEWSQKDLEGPIKYAREHLTKSKMEAFSPERLASYHQELELRAEQGH
PTTFVDLWALVLESMLHGQVMDQKLSEQRAALEQGQNPLPLYLSLNVKENNLETLDFKEW
VEFSPYEVGFLKYGAFVPAELFGSEFFMGRLMRRLPESRICFLEGIWSNIFSLNLLDVWY
GLISSDDTRKQHIKDKIRSLEESPASSKTSSWLEASWLQPGTALARAFKGLLTDRPLHQH
SCNFLRGLQLHQDYRSQKDFSTWADCQLDSTASQLTPQEPQLCLVDAGYFLNTSCPSMFR
SGRRLDLILAFDYSLPSPFEALQQTEVYCRARGLPFPRVEPSPQDQRQPTECHLFSDPSC
PDAPVLLHFPLVNASFRDHSAPGVRRSPAELPAGQVDLTGTASPYSLFNMTYKEEDFDRL
LQLSDYNVRNSQGAILQALRTAVKHRALGARPPAAQN
NT seq
2454 nt
NT seq
+upstream
nt +downstream
nt
atggaaagactgacaactaggggaccacctggccgccctcaccagggggaggcctctgct
tgctggcggctcactgtgagggttctggaggcacggaacctgggctggactgacctgttg
agtgaggcagacccctatgtgaccctacagctgcccaccgtccctggaacaaagtttaag
accaaaacaatcaccaactccagtcatcctgtgtggaatgagaccttcagtttcctaatc
cagagtcaggtcaagaatgtcctggagctaaatgtctatgatgaggactcagtcacggaa
gatgatgcctgcttcaagtttctctatgacgtctcagaagtcctccccggcaagctgctc
cggaagaccttctccctgcagccccagggacaggaggagctggacgtggagttcctgctg
gaaaaaacgtcagactgtccagaaaacctcatcaccaacaacgtccttgtggcccgagag
ctgtcatgcctggatgtccatctggaccacacagagagcgtagccaccgtcacagatcag
gccaagctggagctggagctcgtgctgacgggatcctatgaaaacacacagacatctgcg
ctggggccagcctctgccttccgcttccattacatggcagcccaagacgcagagctgagt
gcgcgtgtgaggagctctgaaagcaatggctggaattccgacaagacagctgggcacctc
actgtgcccctgaggtcactggccatgggaaaggaggtgacgattaacattcccgctaca
aataccccaggagtgaggctgcagctcgagactgagagctgccctaagaagctggctgtg
cacctgggctttgatctgtgcgcagaggagcaggccttcctgagcaggaggaaacaggtg
gtcgccaaggctctcaagcaggccctgcagctggacagagacctacaggaggatgaggtc
cctgtggtgggtatcatggccacaggaggaggtgcccgggccatgacctctctctacggc
cacctgttggcgctgcagaagctgggcctcctggactgtgtgacctacttcagcggcatc
tcaggctctacatggacaatggcccacctctacggggaccctgagtggtcacagaaggac
ctcgaaggacccatcaaatatgccagggaacacctgaccaagagcaagatggaggccttc
tccccagagcgcctagcaagctaccaccaggagctggaactgcgggcggagcagggccac
cccacgacttttgtggacctgtgggctctcgtgctggagtccatgctgcacggccaggtg
atggatcagaagctgtcggaacagagagcagcactggagcagggccagaaccctctgccc
ctctacttgagcctcaatgtcaaagagaacaatctggagaccctcgacttcaaggagtgg
gtggagttttccccctatgaggtcgggttcctgaagtatggagccttcgtccctgccgag
ctcttcggctccgagttcttcatgggccggctgatgaggaggctccctgagtcccggatc
tgctttctggaaggtatctggagcaacattttctccctgaacttgctggatgtctggtac
ggcctcatcagctctgatgacacccgcaagcagcacatcaaggacaagatcaggagcctg
gaggagtctcctgcctcctcgaagacctcctcatggttggaggcctcatggctgcaaccc
gggacagcactggccagggcgtttaagggcttgctgacggacaggccgctccaccagcac
agctgcaacttcctccggggcctccagctgcaccaggactaccgtagccagaaagacttc
tccacctgggcagactgccagctagactccaccgctagccagctgactcctcaggagccc
cagctctgcctggtagatgccggctacttcctcaacaccagctgtccctccatgttccgg
tcaggccgcaggctggacctcatacttgccttcgactactccctaccctcgccctttgag
gcactgcagcagactgaggtgtactgccgggcccggggactgccattccctcgagtggag
cccagccctcaggaccaacgccagccaacagagtgccacctcttctcagacccctcctgc
cccgatgccccggtcctgctgcacttcccactggtcaacgcctccttcagggaccactca
gcccccggtgtccggcgcagccccgcagagctcccagccggccaggtggatctcactggg
accgcctccccctactccctgttcaacatgacctacaaggaggaagactttgatcgtctg
ctgcagcttagtgactataacgtacggaacagccagggcgccattctgcaggccttgagg
actgccgtgaagcaccgggccctgggcgccaggcctccagcggcacagaattga
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