Ursus arctos horribilis (North American brown bear): 113246056
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Entry
113246056 CDS
T05909
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X1
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00230
Purine metabolism
uah01100
Metabolic pathways
uah01522
Endocrine resistance
uah04015
Rap1 signaling pathway
uah04020
Calcium signaling pathway
uah04022
cGMP-PKG signaling pathway
uah04024
cAMP signaling pathway
uah04062
Chemokine signaling pathway
uah04072
Phospholipase D signaling pathway
uah04114
Oocyte meiosis
uah04211
Longevity regulating pathway
uah04213
Longevity regulating pathway - multiple species
uah04261
Adrenergic signaling in cardiomyocytes
uah04270
Vascular smooth muscle contraction
uah04371
Apelin signaling pathway
uah04540
Gap junction
uah04611
Platelet activation
uah04713
Circadian entrainment
uah04714
Thermogenesis
uah04723
Retrograde endocannabinoid signaling
uah04724
Glutamatergic synapse
uah04725
Cholinergic synapse
uah04727
GABAergic synapse
uah04742
Taste transduction
uah04750
Inflammatory mediator regulation of TRP channels
uah04911
Insulin secretion
uah04912
GnRH signaling pathway
uah04913
Ovarian steroidogenesis
uah04914
Progesterone-mediated oocyte maturation
uah04915
Estrogen signaling pathway
uah04916
Melanogenesis
uah04918
Thyroid hormone synthesis
uah04921
Oxytocin signaling pathway
uah04923
Regulation of lipolysis in adipocytes
uah04925
Aldosterone synthesis and secretion
uah04926
Relaxin signaling pathway
uah04927
Cortisol synthesis and secretion
uah04928
Parathyroid hormone synthesis, secretion and action
uah04934
Cushing syndrome
uah04935
Growth hormone synthesis, secretion and action
uah04970
Salivary secretion
uah04971
Gastric acid secretion
uah04972
Pancreatic secretion
uah04976
Bile secretion
uah05032
Morphine addiction
uah05163
Human cytomegalovirus infection
uah05166
Human T-cell leukemia virus 1 infection
uah05200
Pathways in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113246056 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
113246056 (ADCY4)
04371 Apelin signaling pathway
113246056 (ADCY4)
04020 Calcium signaling pathway
113246056 (ADCY4)
04072 Phospholipase D signaling pathway
113246056 (ADCY4)
04024 cAMP signaling pathway
113246056 (ADCY4)
04022 cGMP-PKG signaling pathway
113246056 (ADCY4)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
113246056 (ADCY4)
09144 Cellular community - eukaryotes
04540 Gap junction
113246056 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113246056 (ADCY4)
04062 Chemokine signaling pathway
113246056 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
113246056 (ADCY4)
04923 Regulation of lipolysis in adipocytes
113246056 (ADCY4)
04912 GnRH signaling pathway
113246056 (ADCY4)
04913 Ovarian steroidogenesis
113246056 (ADCY4)
04915 Estrogen signaling pathway
113246056 (ADCY4)
04914 Progesterone-mediated oocyte maturation
113246056 (ADCY4)
04921 Oxytocin signaling pathway
113246056 (ADCY4)
04926 Relaxin signaling pathway
113246056 (ADCY4)
04935 Growth hormone synthesis, secretion and action
113246056 (ADCY4)
04918 Thyroid hormone synthesis
113246056 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
113246056 (ADCY4)
04916 Melanogenesis
113246056 (ADCY4)
04925 Aldosterone synthesis and secretion
113246056 (ADCY4)
04927 Cortisol synthesis and secretion
113246056 (ADCY4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
113246056 (ADCY4)
04270 Vascular smooth muscle contraction
113246056 (ADCY4)
09154 Digestive system
04970 Salivary secretion
113246056 (ADCY4)
04971 Gastric acid secretion
113246056 (ADCY4)
04972 Pancreatic secretion
113246056 (ADCY4)
04976 Bile secretion
113246056 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
113246056 (ADCY4)
04727 GABAergic synapse
113246056 (ADCY4)
04725 Cholinergic synapse
113246056 (ADCY4)
04723 Retrograde endocannabinoid signaling
113246056 (ADCY4)
09157 Sensory system
04742 Taste transduction
113246056 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
113246056 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
113246056 (ADCY4)
04213 Longevity regulating pathway - multiple species
113246056 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
113246056 (ADCY4)
04714 Thermogenesis
113246056 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113246056 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
113246056 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
113246056 (ADCY4)
05163 Human cytomegalovirus infection
113246056 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
113246056 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
113246056 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
113246056 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
113246056 (ADCY4)
Enzymes [BR:
uah01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
113246056 (ADCY4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
CD52
Motif
Other DBs
NCBI-GeneID:
113246056
NCBI-ProteinID:
XP_026342277
LinkDB
All DBs
Position
Unknown
AA seq
1126 aa
AA seq
DB search
MPTGGGESVGLPPDLPRRGSRCPLLLEHFLGLGWRGDYTQTCAQGRESPEQIGQIWVHSF
LSAFCEAGFFTCFRTPGWCSNSCLTDEKTSSARSRIHKRAIWDLASDRGFLTTVLCALGG
FSLLLGLASREQRLQRWTRPLSVLVWAALLGLGHGFLFTGGLVSAWDQVSFFLFVIFTVY
AMLPLGMRDAAAAGLASSLSHLLALGLYLGPQPDSRPALLPQLAANAVLFLCGNVAGAYH
KALMERALRATFREALRSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQ
GSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKE
HECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHS
GSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAGVYAVEDASMEH
RDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPQMRPSLLMTRYLESWGAAKPF
AHLSHLESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDEDLDTGDAKFFQVIEQLNSQ
KQWKQSKDFNPLTLYFREKELEKEYRLSALPAFKYYAACTFLVFFSNFIIQMLVANRPPA
LAITYSITFLLFLLLLFVCFSEHLTKCVLKGPKMLHWLPALSGLVATRPGLRVALGTATI
LLVFVMAITSLFFLPAATNCPSRASNVSSVASNVSWELPGSLPLISVPYSMHCCVLGFLS
CSLFLHMSFELKLLLLLLWLGVSCSLFLHSHAWLSDCLIARLYPDPLDSRPGVLKEPKLM
GAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRLLLENVLPAHVA
PQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIADFDE
LLSKPKFSGVEKIKTIGSTYMAATGLNATPGQDAQQDAERSCSHLGTMVEFAVALGSKLD
VINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEE
TARVLQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG
NT seq
3381 nt
NT seq
+upstream
nt +downstream
nt
atgcccacagggggtggtgaaagtgtagggctcccccctgacctgccacgaagaggttcc
aggtgccccctgctgctggagcacttcttagggctggggtggagaggggattacacccag
acttgtgcccagggcagggaatctcctgagcaaattggccagatttgggtacactcattc
ctaagtgccttctgtgaggcagggtttttcacttgcttcaggaccccaggatggtgctct
aattcctgtttgacagatgagaaaacgagctcagcaaggtcacggattcacaaacgcgcc
atatgggatctagcttcagaccggggcttcctgaccaccgtgctgtgtgcgctcggtggc
ttctcgctgctcctgggcctggcttcccgcgagcaacgactgcagcgctggacacgtccc
ctgtcggtcctcgtgtgggccgcgctactcgggctaggccatggcttcctgttcaccggg
ggcctggtgagcgcctgggaccaggtgtcctttttcctcttcgtcatcttcaccgtgtac
gccatgttgcccttgggcatgcgggatgccgccgccgcgggccttgcctcgtcgctttcc
cacctgctggcccttgggctgtaccttgggcctcagccggactccaggccagcgctgctg
ccgcagctggcagcgaacgccgtgttgttcttgtgcgggaacgtggccggagcgtaccac
aaggcgctgatggagcgcgctctgcgcgccacgttccgggaggctcttcgttccctgcac
tcgcgccggcggctggacacagagaagaagcaccaggaacaccttctcttgtccattctt
cctgcctacctggcccgagagatgaaggcagagatcatggcacggctgcaggctggacag
gggtcccggccagagagcaccaacaacttccacagcctctatgtcaagaggcaccaggga
gtgagcgtgctgtatgctgacatcgtgggcttcacacggctggccagtgagtgctcccct
aaggagctggtgctcatgctcaacgagctcttcggcaagttcgaccagattgccaaggag
catgaatgcatgcggatcaagatcctgggagactgttactactgtgtctctggtctaccg
ctctccctgccagaccacgccatcaactgcgtgcgcatggggctggacatgtgccgggcc
atcaggaaactccgggcggccactggcgtggacatcaacatgcgtgtgggcgtgcattcg
ggcagtgtgctctgcggagtcattgggctgcagaagtggcagtatgatgtctggtcccat
gatgtcacactggccaaccacatggaggcgggcggcgtgccaggacgagtacatattaca
ggggctaccctggccctgctggccggggtctatgctgtggaagatgcatcgatggaacac
cgggacccataccttcgggagctaggggagcccacctacctagtcatcgacccccgggct
gaggaggaggatgagaagggcactgcgggagggctgctgtcctctctcgagggcccccag
atgcgcccatcactgctgatgacccgctacctggagtcctggggcgcggccaagcctttt
gcccatctgagccacctagagagccctgtgtccacttccacccctctcccggagaaggcc
ctggcctccttcagcccccagtggagcctggaccggagccgtaccccccggggactagat
gaggacctggacactggggatgccaagttcttccaggtcatcgaacagctcaactctcag
aagcagtggaagcagtccaaggacttcaacccactgacactgtacttcagagagaaggag
ctggagaaagagtatcgactttctgccctccccgccttcaaatactatgcggcctgcacc
ttcctggtcttcttctccaacttcatcatccagatgctggtggccaacaggccgccagct
ctggccatcacctatagcatcaccttcctcctcttcctcctcctcctcttcgtctgcttc
tcagagcacctgacgaagtgtgtcttgaaaggccccaagatgctgcactggctgcccgca
ctgtctggcttggtggccacacggcccggactccgagttgccctgggcactgccaccatc
ctcctcgtttttgtcatggctattaccagcctgttcttcttaccggcggcaacaaactgc
ccttcccgggcttccaatgtgtcctccgtggcttccaacgtctcctgggagctccctggc
tccctgcctctcatcagcgtcccatactctatgcactgctgcgtgctggggttcctgtcc
tgctccctctttctgcacatgagcttcgagctgaagttgctgctgctcctgctatggctg
ggggtctcctgctccctcttcctgcactcccacgcctggctgtccgactgcctcatcgcc
cgcctctatccagatcccttggactccaggccaggggtgctgaaggagcccaaactgatg
ggagctatctccttcttcatcttcttcttcaccctccttgtcctggctcggcagaatgag
tactactgccgcctggacttcctgtggaagaagaagctgcggcaggagcaggaggagaca
gagaccatggagaacctgactcggctgctgctggagaatgtgctccctgcgcacgtggcc
ccccagttcattggccagaaccggcgcaacgaggacctctaccaccagtcctacgagtgt
gtctgtgtcctcttcgcctcagttccagactttaaggagttttactctgaatctaacatc
aaccacgagggtctagagtgtctgcggttgctcaatgagatcatcgctgattttgatgag
ctgctctcaaagcccaagtttagcggcgtggagaagatcaaaaccatcggcagcacctac
atggcagccacgggcttaaatgccacccccggacaggacgcacagcaggatgccgagcga
agctgcagccacctgggcaccatggtggagttcgcagtggccctcggatcgaagctggat
gtcatcaacaagcactcattcaacaacttccgcctgcgtgtggggttgaaccacggacct
gtagtggctggagtgattggggcccagaagcctcagtatgacatctggggcaacacggtg
aacgtggccagccgcatggaaagtacgggagtcctgggcaagatccaagtgactgaagag
acagcccgggtgctgcagtccttaggctatacctgctacagccggggcatcatcaaggtc
aaaggcaaagggcagctgtgcacctacttcctgaacacagatttgacacgaactggccct
ccctcggccaccctaggctga
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