Ursus arctos horribilis (North American brown bear): 113257829
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Entry
113257829 CDS
T05909
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00230
Purine metabolism
uah01100
Metabolic pathways
uah04022
cGMP-PKG signaling pathway
uah04024
cAMP signaling pathway
uah04924
Renin secretion
uah05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113257829 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
113257829 (PDE3A)
04022 cGMP-PKG signaling pathway
113257829 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
113257829 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
113257829 (PDE3A)
Enzymes [BR:
uah01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
113257829 (PDE3A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
113257829
NCBI-ProteinID:
XP_026358103
LinkDB
All DBs
Position
Unknown
AA seq
1142 aa
AA seq
DB search
MAVLREAARVGDKPDHGGVYQAPAAGPDCPAGAGPARSRDSGSRGRWGDLVLRPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEIGRDLEQSKEAATAAAEETAPGAEGGVFPGLRGGAP
GGGAPLSPWLQLSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLGV
GEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPYL
AYLAGVLGLLLARYVEQILPQSAGAAPREHFGSQQIAGTKEDIPVFKRRRRSSSVVSAEM
SGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDL
LADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRMNPVVSFSENYTCSDSEEGSEKDKLA
IPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEASSLSAVSPD
SWNNPVMMTLTKSRSFTSSYAVSAANHVNSRKPNRPGALAKISPLSSPCSSPPQGTPVSS
PVSKISAVRFPESANTSARQGLGSHRALTYTQSAPDLSPQILPPPVICSSCGRPYPQGNA
ADGPLEGNSAAVRTPSRTDDTTQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACG
PYTPEAMIFLDKPVLAPEPLVMDNLDSIMEQLNTWNFPIFDLVEKIGRKRGRILSQVSYR
LFEDMGLFEAFKIPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGHST
VMNDHGSASDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHD
YDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHF
RFLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKC
KELHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYD
SAGLMPGKWVEDSDESGDTDDPEEEEEEAANEEETCENNESPRKKTFKRRKIYCQITQHL
LQNHKMWKKVIEEEQRLAGIENPSLDPSPQQHPSEQIQAIREEEEEKGKPRGEEILTPEQ
NQ
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgctccgcgaggccgcgcgagtcggggacaagcccgaccacggtggggtgtat
caagcccccgcggcgggcccggactgtcccgctggcgccggccccgcacggtcgcgggac
tccggcagccgcggccgctggggagacctggtgctgcggccgctccggcgctcccggaaa
ctttcctcagcgctgtgcgcgggctccttgtcctttctgctggccctgctggtgaggctg
gtgcgcggggagatcggccgcgacctggagcagagtaaggaggcggcgacggccgctgcg
gaggaaacggccccgggagcagaagggggcgtcttcccggggcttcggggaggtgctcct
gggggcggcgcgccgctcagcccctggctgcagctctcagcgctgctcttcagtcttctg
tgtgccttcttctggatgggcttgtacctcctgcgcgccggggtgcgcctgcctctggcc
gtcgcactgctcgccgcctgctgcgggggggaagcgctcgtccagattgggctgggcgtc
ggggaggatcacttactctcgctgccggccgcgggggtggtgctcagctgcttggccgcc
gcgacatggctggtgctgaggctgaggctgggcgtcctcatgatcgccttgactagcgcg
gtcaggactgtgtccctcatttccttagagaggttcaaggtcgcctggagaccttacctg
gcatacttggccggcgtgttggggctcctcctggccaggtacgtggagcaaatcttgccg
cagtctgcgggggcggctccgagggagcatttcgggtcccagcaaattgctgggaccaag
gaagatatcccagtatttaagaggaggaggcggtccagctccgtggtgtccgcggagatg
tccggctgcagcagcaagtcccatcggaggacctccctgccctgcataccgagggaacag
ctcatggggcattcagaatgggaccacaaacgagggccaagaggatcacagtcctcagga
accagtattaccgtggatattgccgtgatgggggaggctcacggcctcattaccgacctc
ctggcagacccttcgctgccccccaacgtgtgcacatccttgagggcagtaagcaacctg
ctcagcacccagctcaccttccaggctattcacaagccccgcatgaatcctgttgtttcc
ttcagtgaaaattacacctgttctgattccgaggaaggctctgaaaaagacaagctggct
attcccaagcgcctgagaaggagtttgcctcctggtttgttgagacgagtttcatcaacc
tggacaaccaccacctcagccacaggcctgcccactttggagcctgccccagtacggagg
gaccggagcgcaagcatcaaactacatgaggcatcttcattgagtgctgttagtcccgat
tcttggaataacccggtgatgatgaccctcaccaaaagcagatccttcacttcatcctat
gctgtttctgcagctaaccatgtaaactcaagaaagccaaatcgaccaggtgccctagcg
aaaatttctcctctttcatcgccctgttcctcacctccccaagggactcctgtcagcagc
cccgtcagcaaaatttctgcagtgcggtttccagaatctgccaacacaagtgctagacaa
ggcctaggttctcacagggcattaacttatactcagagtgcccctgacctgtctcctcag
atcctccctccacctgttatatgtagcagctgtggtagaccctatccccaagggaatgct
gctgatggacccctggagggaaacagtgcagccgttcggacaccaagcagaacagatgac
actactcaagttacctctgattatgaaaccaacaacaacagtgatagcagtgatattgta
cagaacgaagatgagaccgagtgcctgagagagcctctaaggaaagcttctgcttgtggc
ccctacacgcctgaagccatgatattcctggacaagccagttcttgctcctgaacctctt
gtcatggataacttggactcaattatggagcagctaaatacttggaattttccaattttt
gatttggtggaaaaaataggaagaaaacgtggccgtattcttagtcaggtatcatacagg
ctttttgaagacatgggcctctttgaagctttcaaaattccagttagggaatttatgaat
tattttcatgctttggagattggatacagagagattccttatcataacagaatccatgcc
actgatgtgttacacgctgtgtggtatcttactacgcaaccaattccaggccactccact
gtgatgaatgatcatggatcagcaagtgattcagattctgacagtggatttacccatgga
catatgggatatgtcttctcaaaaatgtataatgtgcccgatgataaatacggatgtctc
tctggaaatatcccagccttagagttaatggcattgtatgtggctgcggccatgcacgat
tacgatcacccaggaaggactaacgctttcctggttgcaactagtgctccccaggcggtg
ctctataatgatcgttcagttttggagaatcatcacgcagctgctgcttggaatcttttc
atgtcccggccggagtacaacttcttagttaaccttgaccatgtggaatttaagcatttt
cgtttccttgtcattgaagcaattttggccactgacctgaagaaacactttgattttgta
gccaaatttaatgccaaggtgaatgatgatgttggaatagattggaccaatgaaaatgat
cgcctcctggtttgccaaatgtgtataaagttggctgatatcaatgggccagctaaatgt
aaagagctccatcttcagtggacagagggtattgtcaatgaattttatgaacagggtgat
gaagaggccagccttgggttaccaataagccccttcatggaccgttctgctcctcagttg
gccaatcttcaggaatccttcatctctcacattgtgggtcctctgtgcaactcctatgat
tcagcaggactaatgccagggaagtgggtggaagatagtgatgagtcaggagatactgat
gacccagaagaagaggaggaggaagcagcaaacgaagaggaaacctgtgaaaataatgaa
tctccaagaaagaaaactttcaaaaggaggaaaatctactgccaaataactcagcacctc
ctgcagaaccacaagatgtggaagaaagtcattgaagaggaacagcggttggcaggcata
gagaatccgtccctggacccgtccccccagcagcatccctcagaacagatccaggccatc
agggaagaagaggaagagaaagggaagccgcgaggagaggagatcctgaccccggaacaa
aaccagtga
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