Ursus arctos horribilis (North American brown bear): 113258578
Help
Entry
113258578 CDS
T05909
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah01522
Endocrine resistance
uah04012
ErbB signaling pathway
uah04015
Rap1 signaling pathway
uah04062
Chemokine signaling pathway
uah04137
Mitophagy - animal
uah04144
Endocytosis
uah04360
Axon guidance
uah04370
VEGF signaling pathway
uah04510
Focal adhesion
uah04520
Adherens junction
uah04530
Tight junction
uah04540
Gap junction
uah04611
Platelet activation
uah04613
Neutrophil extracellular trap formation
uah04625
C-type lectin receptor signaling pathway
uah04727
GABAergic synapse
uah04750
Inflammatory mediator regulation of TRP channels
uah04810
Regulation of actin cytoskeleton
uah04912
GnRH signaling pathway
uah04915
Estrogen signaling pathway
uah04917
Prolactin signaling pathway
uah04919
Thyroid hormone signaling pathway
uah04921
Oxytocin signaling pathway
uah04926
Relaxin signaling pathway
uah05100
Bacterial invasion of epithelial cells
uah05135
Yersinia infection
uah05152
Tuberculosis
uah05161
Hepatitis B
uah05163
Human cytomegalovirus infection
uah05167
Kaposi sarcoma-associated herpesvirus infection
uah05168
Herpes simplex virus 1 infection
uah05203
Viral carcinogenesis
uah05205
Proteoglycans in cancer
uah05207
Chemical carcinogenesis - receptor activation
uah05208
Chemical carcinogenesis - reactive oxygen species
uah05219
Bladder cancer
uah05417
Lipid and atherosclerosis
uah05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
113258578 (SRC)
04015 Rap1 signaling pathway
113258578 (SRC)
04370 VEGF signaling pathway
113258578 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113258578 (SRC)
04137 Mitophagy - animal
113258578 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113258578 (SRC)
04520 Adherens junction
113258578 (SRC)
04530 Tight junction
113258578 (SRC)
04540 Gap junction
113258578 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113258578 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113258578 (SRC)
04613 Neutrophil extracellular trap formation
113258578 (SRC)
04625 C-type lectin receptor signaling pathway
113258578 (SRC)
04062 Chemokine signaling pathway
113258578 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
113258578 (SRC)
04915 Estrogen signaling pathway
113258578 (SRC)
04917 Prolactin signaling pathway
113258578 (SRC)
04921 Oxytocin signaling pathway
113258578 (SRC)
04926 Relaxin signaling pathway
113258578 (SRC)
04919 Thyroid hormone signaling pathway
113258578 (SRC)
09156 Nervous system
04727 GABAergic synapse
113258578 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
113258578 (SRC)
09158 Development and regeneration
04360 Axon guidance
113258578 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
113258578 (SRC)
05207 Chemical carcinogenesis - receptor activation
113258578 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
113258578 (SRC)
05203 Viral carcinogenesis
113258578 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
113258578 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
113258578 (SRC)
05168 Herpes simplex virus 1 infection
113258578 (SRC)
05163 Human cytomegalovirus infection
113258578 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
113258578 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
113258578 (SRC)
05152 Tuberculosis
113258578 (SRC)
05100 Bacterial invasion of epithelial cells
113258578 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113258578 (SRC)
05418 Fluid shear stress and atherosclerosis
113258578 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113258578 (SRC)
01522 Endocrine resistance
113258578 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113258578 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uah04131
]
113258578 (SRC)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113258578 (SRC)
Protein kinases [BR:
uah01001
]
Non-receptor tyrosine kinases
SRC family
113258578 (SRC)
Membrane trafficking [BR:
uah04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
113258578 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
113258578 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
113258578 (SRC)
Macropinocytosis
Kinases
113258578 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH3_10
ABC1
Haspin_kinase
SH3_3
Motif
Other DBs
NCBI-GeneID:
113258578
NCBI-ProteinID:
XP_026359256
LinkDB
All DBs
Position
Unknown
AA seq
536 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagccc
gctgagaacacccacggtggcggcgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccctagtacggccttcccctccgcagctgccgag
cccaagctgttcgggggcttcaactcgtcagacacagtcacctccccacagagggcgggg
ccgctggctggtggagtgaccacctttgtggccctctacgactatgagtctcggacagag
accgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacagagggtgac
tggtggctggcccactcgctcagcacgggacagacgggttacatccctagcaactatgtg
gcgccctccgactctatccaggccgaggagtggtactttggcaagatcaccagacgggag
tcggaacggttactgctcaatgcggagaacccgagagggaccttcctagtgcgagaaagt
gagaccacgaaaggtgcctactgcctctccgtgtctgatttcgacaacgccaagggcctc
aacgtgaagcactacaagatccgcaagctggacagcggcggcttctacatcacgtcccgc
acccagttcaacagtctgcagcagctggtggcctactactccaaacatgctgacggcctg
tgccaccgcctcaccactgtgtgccctacgtccaagccccagactcagggcctggccaag
gatgcctgggagatccctcgggagtccctgcggctggaggtcaagctgggccaaggctgt
ttcggagaggtgtggatggggacctggaatggaaccaccagggtggccatcaaaaccctg
aagccaggcacgatgtctccggaggccttcctgcaggaggcccaggtcatgaagaaactg
aggcacgagaagctggtgcagctgtatgcggtggtgtctgaggaacctatctacatcgtc
acggagtacatgagcaaggggagtctgctggactttctcaagggggagacgggcaagtac
ctgcggctgcctcagctggtggacatggctgctcagatcgcctcaggcatggcctacgtg
gaacggatgaactatgtccaccgggacctccgtgctgccaacatcctggttggagagaac
ctcgtgtgcaaagtggctgactttgggctggctcggctcatcgaagacaatgagtacacg
gcccggcaaggtgccaaattccccatcaagtggacagctcccgaagcggccctctacggc
cggttcaccatcaagtcagatgtatggtcctttgggatcctgctgacggagctcacaaca
aagggacgggtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcgg
ggctaccgaatgccctgcccgcccgagtgtcccgagtccctgcacgacctcatgtgccag
tgctggcggaaggagccggaggagcggcccaccttcgagtacctgcaggccttcctggaa
gactacttcacgtccaccgagccccagtaccagcctggagagaacctatag
DBGET
integrated database retrieval system