KEGG   Ursus arctos horribilis (North American brown bear): 113264969
Entry
113264969         CDS       T05909                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2
  KO
K10140  DNA damage-binding protein 2
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah03420  Nucleotide excision repair
uah04115  p53 signaling pathway
uah04120  Ubiquitin mediated proteolysis
uah05161  Hepatitis B
uah05169  Epstein-Barr virus infection
uah05200  Pathways in cancer
uah05202  Transcriptional misregulation in cancer
uah05210  Colorectal cancer
uah05212  Pancreatic cancer
uah05213  Endometrial cancer
uah05214  Glioma
uah05216  Thyroid cancer
uah05217  Basal cell carcinoma
uah05218  Melanoma
uah05220  Chronic myeloid leukemia
uah05222  Small cell lung cancer
uah05223  Non-small cell lung cancer
uah05224  Breast cancer
uah05225  Hepatocellular carcinoma
uah05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:uah00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    113264969 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    113264969 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    113264969 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113264969 (DDB2)
   05202 Transcriptional misregulation in cancer
    113264969 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    113264969 (DDB2)
   05212 Pancreatic cancer
    113264969 (DDB2)
   05225 Hepatocellular carcinoma
    113264969 (DDB2)
   05226 Gastric cancer
    113264969 (DDB2)
   05214 Glioma
    113264969 (DDB2)
   05216 Thyroid cancer
    113264969 (DDB2)
   05220 Chronic myeloid leukemia
    113264969 (DDB2)
   05217 Basal cell carcinoma
    113264969 (DDB2)
   05218 Melanoma
    113264969 (DDB2)
   05213 Endometrial cancer
    113264969 (DDB2)
   05224 Breast cancer
    113264969 (DDB2)
   05222 Small cell lung cancer
    113264969 (DDB2)
   05223 Non-small cell lung cancer
    113264969 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    113264969 (DDB2)
   05169 Epstein-Barr virus infection
    113264969 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:uah04121]
    113264969 (DDB2)
   03400 DNA repair and recombination proteins [BR:uah03400]
    113264969 (DDB2)
Ubiquitin system [BR:uah04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     113264969 (DDB2)
DNA repair and recombination proteins [BR:uah03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      113264969 (DDB2)
SSDB
Motif
Pfam: WD40 NBCH_WD40 EF-hand_1
Other DBs
NCBI-GeneID: 113264969
NCBI-ProteinID: XP_026367759
LinkDB
Position
Unknown
AA seq 426 aa
MAPRKRPETQKTPEVSVRPKSKRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVPPSYSIVRALHQHKLGNAAWPSLQQGLQQAFLHSLASYRIFQKAAPFDRRATSLAWHP
THPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLDTNQFFTSSMEGTT
RLQDFKGNTLRVFTSSGTCNFWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRMH
KKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLHSLPHSHPVNAACFSPDGA
QLLTTDQKSELRVYSASQWDCPPSLIPHPHRHFQHLTPIKATWHPRYNLIVVGRYPDPNF
KSCTPHELRTIDVFDGNSGKMMYQLYDPESSGIISLNEFNSMGDTLASVMGYHILIWSQE
EAGRRT
NT seq 1281 nt   +upstreamnt  +downstreamnt
atggctcctaggaaacgcccagaaacccagaagacccccgaggtgtctgtgcgccccaag
agcaagaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcgggctgcctttgggcggggttggctagcctg
caggtcccgccatcatacagcatcgtcagggccctccaccagcataagctgggcaacgct
gcctggccatcgctgcaacagggtctccagcaggcctttctgcactctctggcttcttac
cggatattccaaaaggctgccccctttgacaggagggccacatccttggcatggcaccca
actcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaacttt
ggcataaaggacaaacccaccttcattaaagggattggagctggagggagcatcactggg
ctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaacaact
aggctgcaagactttaaaggcaacacgctccgagtttttaccagctcaggcacctgcaac
ttctggttttgcagtctggatgtgtctgccagaagccgaatggtggtcacgggagacaat
gtggggcacgtgatcctgctgaacatggatggcagggagctttggaatctgagaatgcac
aaaaagaaagtgacccacgtggccttgaacccatgctgtgattggttcctggccacagcc
tccgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagcttc
ctccactcgctgccgcatagccatcctgtcaacgcagcttgttttagtcctgatggagcc
cagctcctgaccactgaccagaagagtgagctccgggtttattcggcctcccagtgggac
tgccccccgagcctgatcccacaccctcaccgccacttccagcacctgacgcccatcaag
gcaacctggcatcctcggtacaacctcattgtcgtgggccggtacccagatcctaatttc
aaaagctgtacaccccatgaattaaggaccattgatgtgtttgatggaaactcagggaag
atgatgtatcagctctatgacccagaatcttctggtatcatttcgctcaatgagttcaat
tccatgggggacacgctggcctctgtgatgggttatcacattctcatttggagccaggag
gaagctggaaggcggacatga

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