Ursus arctos horribilis (North American brown bear): 113268019
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Entry
113268019 CDS
T05909
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah05200
Pathways in cancer
uah05223
Non-small cell lung cancer
uah05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113268019 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
113268019 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
113268019 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113268019 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
uah04090
]
113268019 (ALK)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113268019 (ALK)
Protein kinases [BR:
uah01001
]
Receptor tyrosine kinases (RTK)
ALK family
113268019 (ALK)
CD molecules [BR:
uah04090
]
Proteins
113268019 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Gly_rich
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
113268019
NCBI-ProteinID:
XP_026372163
LinkDB
All DBs
Position
Unknown
AA seq
875 aa
AA seq
DB search
MCFHWLFTTCGASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPATDTYSISG
YGAAGGKGGKNTMMRSHGVSVLGIFNLEKGDMLYILVGQQGEDACPSTNRLIQKVCIGEN
NVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGAKTDTFHP
ERLENNSSVLGLNGNSGAAGGNAASNNDPEIDGEDGVSFISPLGILYTPALKVMEGHGEV
NIKHYLNCSHCEGDECHMDPESHKVICFCDHGTVLADDGVSCIVSPTPEPHLPLSLVLSV
VTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFA
GKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGVPSDPSPLQVAVKTLPEVCSEQ
DELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGGDLKSFLRETRPRPNQPS
SLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYR
ASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVL
EFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVIHTALPV
EYGPLVEEEEKVPVRPQDPEGIPPLLVSPPQANREEGREPAAPPPLPSASSGRAVKKPAA
AEPSVRGARAPAVEGGHVNMAFSQSNPPSELHKVQGSRNKPTSLWNPTYGSWFTEKPARK
TNPPAKKERHERGTPGREGSCAVAPPAAGGRLPGASVLLEPSSLTASVKEVPLFRLRHFP
CGTVNYGYQQQGLPLEAAAGAGRYGDSLLKSRPAP
NT seq
2628 nt
NT seq
+upstream
nt +downstream
nt
atgtgttttcactggctgttcaccacgtgcggggccagcgggccccatggccccacacag
gcccagtgtaacaacgcctaccggaattccaacctgagcgtggtggtggggagcgagggc
cccctgaaaggcatccagacctggaaggtgccagccaccgacacctacagcatctcaggc
tacggagctgctggtgggaaaggcgggaagaacaccatgatgcggtcccacggcgtgtct
gtgctgggcatcttcaacctggagaagggcgacatgctgtatatcctagttggacaacag
ggggaagacgcctgccccagcacaaaccgattaatccagaaagtgtgcattggtgagaac
aacgtgatagaagaagagatccgtgtgaacaggagtgtgcatgagtgggcaggagggggt
ggaggtggaggcggagccacgtacgtgtttaagatgaaggatggcgtgccagtgcccctg
atcattgcagccggcggtggcggcagggcctatggggccaagacagacacgttccaccca
gagagactggagaataactcctcggttctggggctgaacggcaactctggagccgcaggc
ggcaacgcggcctcaaacaatgaccccgagatcgacggggaggacggggtctctttcatc
agtccgctgggcatcctgtatacccccgctttaaaagtgatggagggccatggggaagtg
aatattaagcattatctgaactgcagccactgtgagggagacgagtgccacatggacccc
gagagccacaaggtcatctgcttctgtgaccacgggacagtgctggctgacgatggcgtc
tcctgcattgtgtcccccaccccagagccccacctgccgctctcgctggtcctgtctgtc
gtgacctcagccctcgtggccgccctggtcctggctttctccggcatcatgattgtgtac
cgccggaagcaccaggagctgcaagccatgcagatggagctgcagagccctgagtacaag
ctgagcaagctccgcacctcgaccatcatgaccgactacaaccccaactactgcttcgct
ggcaagacctcgtccatcagcgacctgaaggaggtgcctcggaaaaacatcaccctcatc
cggggactgggccacggtgcattcggggaggtgtatgaaggtcaggtgtccggagtgccc
agcgacccgagccccctgcaagtggctgtaaagacgctgcctgaagtgtgttctgaacag
gacgaactggatttcctcatggaagccctgataatcagcaaattcaaccaccagaacatc
gtgcgctgtattggggtgagtctgcaagccctgccccgatttatcctgctggagctcatg
gcaggaggagacctcaagtccttcctccgggagacccgccctcgcccgaaccagccctcc
tccctggccatgctggaccttctgcacgtggctcgggacatcgcctgtggctgtcagtat
ttggaggaaaatcacttcatccaccgagacattgctgccagaaactgcctcttgacctgt
ccgggccctggcagagtggccaagattggagactttggaatggcccgggacatctacaga
gcgagctactaccgaaaaggaggctgcgccatgctgcccgtcaaatggatgcctccagag
gccttcatggaagggatattcacttctaaaacggacacatggtccttcggcgtgctgctg
tgggaaatattttctcttggatacatgccgtaccccagcaaaagcaaccaagaagttctg
gagttcgtcaccagcggaggacggatggacccacctaagaactgccctgggcccgtatac
cggataatgacccagtgctggcaacatcagcctgaagacaggcccaactttgccataatt
ttggagaggatcgaatactgcacccaggacccggatgtgatccacacggctctgcccgta
gagtacggcccgctggtggaggaggaggagaaggtgcccgtgaggccccaagacccggag
gggatcccgccgctcctcgtctctcccccccaggctaaccgcgaggaggggcgcgagccg
gctgccccgccgcccctgccttccgcgtcctccggcagagccgtgaagaagcccgcggcg
gccgagccgtctgttcgaggcgcgcgggcgccggccgtggaaggaggacacgtgaacatg
gcgttctcccagtccaacccgccttcagagctgcacaaggtccagggatccaggaacaag
ccgaccagcctgtggaaccccacgtacggctcgtggtttacggagaaacccgccagaaag
accaatcctccagccaagaaggagcgccacgagaggggcaccccggggcgggaggggagc
tgtgctgtcgcccctcccgcggcgggcggccggctgccgggagcgtctgtgctgctggag
ccgtcctcgctgacggccagcgtgaaggaggtgcccctgttccggctgcgccacttcccg
tgcggcaccgtcaactacggctaccagcagcagggcctgccgctggaggccgccgccggg
gccgggcgctacggggacagcctgctgaagagccggcccgcgccctga
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