KEGG   Ursus americanus (American black bear): 123778302
Entry
123778302         CDS       T07931                                 
Symbol
RELA
Name
(RefSeq) transcription factor p65
  KO
K04735  transcription factor p65
Organism
uar  Ursus americanus (American black bear)
Pathway
uar01523  Antifolate resistance
uar04010  MAPK signaling pathway
uar04014  Ras signaling pathway
uar04024  cAMP signaling pathway
uar04062  Chemokine signaling pathway
uar04064  NF-kappa B signaling pathway
uar04066  HIF-1 signaling pathway
uar04071  Sphingolipid signaling pathway
uar04137  Mitophagy - animal
uar04151  PI3K-Akt signaling pathway
uar04210  Apoptosis
uar04211  Longevity regulating pathway
uar04218  Cellular senescence
uar04380  Osteoclast differentiation
uar04613  Neutrophil extracellular trap formation
uar04620  Toll-like receptor signaling pathway
uar04621  NOD-like receptor signaling pathway
uar04622  RIG-I-like receptor signaling pathway
uar04623  Cytosolic DNA-sensing pathway
uar04625  C-type lectin receptor signaling pathway
uar04657  IL-17 signaling pathway
uar04658  Th1 and Th2 cell differentiation
uar04659  Th17 cell differentiation
uar04660  T cell receptor signaling pathway
uar04662  B cell receptor signaling pathway
uar04668  TNF signaling pathway
uar04722  Neurotrophin signaling pathway
uar04917  Prolactin signaling pathway
uar04920  Adipocytokine signaling pathway
uar04926  Relaxin signaling pathway
uar04931  Insulin resistance
uar04932  Non-alcoholic fatty liver disease
uar04933  AGE-RAGE signaling pathway in diabetic complications
uar04936  Alcoholic liver disease
uar05010  Alzheimer disease
uar05022  Pathways of neurodegeneration - multiple diseases
uar05030  Cocaine addiction
uar05132  Salmonella infection
uar05133  Pertussis
uar05134  Legionellosis
uar05135  Yersinia infection
uar05140  Leishmaniasis
uar05142  Chagas disease
uar05145  Toxoplasmosis
uar05146  Amoebiasis
uar05152  Tuberculosis
uar05160  Hepatitis C
uar05161  Hepatitis B
uar05162  Measles
uar05163  Human cytomegalovirus infection
uar05164  Influenza A
uar05165  Human papillomavirus infection
uar05166  Human T-cell leukemia virus 1 infection
uar05167  Kaposi sarcoma-associated herpesvirus infection
uar05168  Herpes simplex virus 1 infection
uar05169  Epstein-Barr virus infection
uar05170  Human immunodeficiency virus 1 infection
uar05171  Coronavirus disease - COVID-19
uar05200  Pathways in cancer
uar05202  Transcriptional misregulation in cancer
uar05203  Viral carcinogenesis
uar05207  Chemical carcinogenesis - receptor activation
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05212  Pancreatic cancer
uar05215  Prostate cancer
uar05220  Chronic myeloid leukemia
uar05221  Acute myeloid leukemia
uar05222  Small cell lung cancer
uar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uar05321  Inflammatory bowel disease
uar05415  Diabetic cardiomyopathy
uar05417  Lipid and atherosclerosis
uar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123778302 (RELA)
   04014 Ras signaling pathway
    123778302 (RELA)
   04064 NF-kappa B signaling pathway
    123778302 (RELA)
   04668 TNF signaling pathway
    123778302 (RELA)
   04066 HIF-1 signaling pathway
    123778302 (RELA)
   04071 Sphingolipid signaling pathway
    123778302 (RELA)
   04024 cAMP signaling pathway
    123778302 (RELA)
   04151 PI3K-Akt signaling pathway
    123778302 (RELA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    123778302 (RELA)
  09143 Cell growth and death
   04210 Apoptosis
    123778302 (RELA)
   04218 Cellular senescence
    123778302 (RELA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    123778302 (RELA)
   04620 Toll-like receptor signaling pathway
    123778302 (RELA)
   04621 NOD-like receptor signaling pathway
    123778302 (RELA)
   04622 RIG-I-like receptor signaling pathway
    123778302 (RELA)
   04623 Cytosolic DNA-sensing pathway
    123778302 (RELA)
   04625 C-type lectin receptor signaling pathway
    123778302 (RELA)
   04660 T cell receptor signaling pathway
    123778302 (RELA)
   04658 Th1 and Th2 cell differentiation
    123778302 (RELA)
   04659 Th17 cell differentiation
    123778302 (RELA)
   04657 IL-17 signaling pathway
    123778302 (RELA)
   04662 B cell receptor signaling pathway
    123778302 (RELA)
   04062 Chemokine signaling pathway
    123778302 (RELA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    123778302 (RELA)
   04917 Prolactin signaling pathway
    123778302 (RELA)
   04926 Relaxin signaling pathway
    123778302 (RELA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123778302 (RELA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123778302 (RELA)
  09149 Aging
   04211 Longevity regulating pathway
    123778302 (RELA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123778302 (RELA)
   05202 Transcriptional misregulation in cancer
    123778302 (RELA)
   05207 Chemical carcinogenesis - receptor activation
    123778302 (RELA)
   05208 Chemical carcinogenesis - reactive oxygen species
    123778302 (RELA)
   05203 Viral carcinogenesis
    123778302 (RELA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123778302 (RELA)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    123778302 (RELA)
   05221 Acute myeloid leukemia
    123778302 (RELA)
   05220 Chronic myeloid leukemia
    123778302 (RELA)
   05215 Prostate cancer
    123778302 (RELA)
   05222 Small cell lung cancer
    123778302 (RELA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123778302 (RELA)
   05170 Human immunodeficiency virus 1 infection
    123778302 (RELA)
   05161 Hepatitis B
    123778302 (RELA)
   05160 Hepatitis C
    123778302 (RELA)
   05171 Coronavirus disease - COVID-19
    123778302 (RELA)
   05164 Influenza A
    123778302 (RELA)
   05162 Measles
    123778302 (RELA)
   05168 Herpes simplex virus 1 infection
    123778302 (RELA)
   05163 Human cytomegalovirus infection
    123778302 (RELA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123778302 (RELA)
   05169 Epstein-Barr virus infection
    123778302 (RELA)
   05165 Human papillomavirus infection
    123778302 (RELA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123778302 (RELA)
   05135 Yersinia infection
    123778302 (RELA)
   05133 Pertussis
    123778302 (RELA)
   05134 Legionellosis
    123778302 (RELA)
   05152 Tuberculosis
    123778302 (RELA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123778302 (RELA)
   05145 Toxoplasmosis
    123778302 (RELA)
   05140 Leishmaniasis
    123778302 (RELA)
   05142 Chagas disease
    123778302 (RELA)
  09163 Immune disease
   05321 Inflammatory bowel disease
    123778302 (RELA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123778302 (RELA)
   05022 Pathways of neurodegeneration - multiple diseases
    123778302 (RELA)
  09165 Substance dependence
   05030 Cocaine addiction
    123778302 (RELA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123778302 (RELA)
   05418 Fluid shear stress and atherosclerosis
    123778302 (RELA)
   05415 Diabetic cardiomyopathy
    123778302 (RELA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123778302 (RELA)
   04932 Non-alcoholic fatty liver disease
    123778302 (RELA)
   04931 Insulin resistance
    123778302 (RELA)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123778302 (RELA)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    123778302 (RELA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:uar03000]
    123778302 (RELA)
Transcription factors [BR:uar03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    123778302 (RELA)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer
Other DBs
NCBI-GeneID: 123778302
NCBI-ProteinID: XP_045631499
LinkDB
Position
Unknown
AA seq 539 aa
MDDLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLRLSPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFNGPTDPRPPPRRIAVPSRSTPSVPKPAPQPYPFTPSLSTINF
EEFSPMVFPSGQIPNQTSALAPAPAPILAQAPAPAPAPILAPGLAQAVVPPAPKTTQAGE
GTLSEALLHLQFDADEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGVSVAPHTAEPM
LMEYPEAITRLVTGSQRPPDPAPAPLGASGLPNGLLSGDEDFSSIADMDFSALLSQISS
NT seq 1620 nt   +upstreamnt  +downstreamnt
atggacgacctgtttcccctcatcttcccgtctgagcccgcccaggcctctggcccctat
gtggagatcatcgagcagcccaagcagcggggcatgcgcttccgctacaagtgcgagggc
cgctcagcgggcagtatcccgggcgagaggagcacggataccaccaagacccaccccacc
atcaagatcaatggctacactgggccagggacagttcgcatctccctggttaccaaggac
ccccctcaccggcctcacccccatgagcttgtggggaaagactgccgggatggcttctat
gaggctgagctctgccccgaccgttgcatccacagcttccagaacctggggatccagtgt
gtaaagaagcgggacctggagcaggccatcagtcaacgcatccagaccaacaacaatccc
ttccaagttcccatcgaagaacagcgtggggactacgacctgaatgcggtgcggctgtgc
ttccaggtgacagtgcgggacccggcaggcaggcccctccgcttgtcacctgtcctctct
catcccatctttgacaaccgtgcccccaacaccgccgagctcaagatctgccgagtgaac
cggaactctgggagctgcctcgggggggatgagatcttcctgctgtgtgacaaggtgcag
aaagaggacatcgaagtgtatttcacgggaccgggctgggaggcccgaggctccttttct
caagctgacgtccaccgacaagtggccattgtgttccggacacctccctacgcggacccc
agcctgcaggcccccgtgcgtgtctccatgcagctgcggcggccttcagatcgggagctc
agcgagcccatggaattccagtacttgccagacacagatgatcgacaccgaattgaggag
aaacgcaaaaggacgtatgagaccttcaagagcatcatgaaaaagagtcctttcaatgga
cccaccgacccccgacctccaccccggcgcattgctgtgccttcccgaagcacaccttcc
gtccccaagccagctccccagccctatccctttacgccgtccctcagcaccatcaacttc
gaggagttctcccccatggtctttccttcggggcagatcccaaaccagacctctgccttg
gccccagcccctgccccaatcctcgcccaggccccggccccagcccctgccccgatctta
gccccaggccttgctcaggctgtggtcccccccgcccccaagaccacccaggccggggaa
gggacactgtcagaggccctgctgcacctgcagtttgacgccgacgaagacctgggggcc
ctgctgggcaacagcactgaccccgccgtgttcacagacctggcatctgtcgacaactct
gagtttcagcagctgctgaaccagggtgtatctgtggccccacacacagccgagcccatg
ctgatggagtaccctgaggcaataacgcgcctggtgacagggtcccagaggccccctgac
ccagctcctgctcccctgggggcctctgggctccccaacggcctcctctcaggggatgaa
gacttctcctccattgcagacatggacttctcagcccttctgagtcagatcagctcctaa

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