KEGG   Ursus americanus (American black bear): 123782828
Entry
123782828         CDS       T07931                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04010  MAPK signaling pathway
uar04020  Calcium signaling pathway
uar04022  cGMP-PKG signaling pathway
uar04114  Oocyte meiosis
uar04218  Cellular senescence
uar04310  Wnt signaling pathway
uar04360  Axon guidance
uar04370  VEGF signaling pathway
uar04380  Osteoclast differentiation
uar04625  C-type lectin receptor signaling pathway
uar04650  Natural killer cell mediated cytotoxicity
uar04658  Th1 and Th2 cell differentiation
uar04659  Th17 cell differentiation
uar04660  T cell receptor signaling pathway
uar04662  B cell receptor signaling pathway
uar04720  Long-term potentiation
uar04724  Glutamatergic synapse
uar04728  Dopaminergic synapse
uar04921  Oxytocin signaling pathway
uar04922  Glucagon signaling pathway
uar04924  Renin secretion
uar05010  Alzheimer disease
uar05014  Amyotrophic lateral sclerosis
uar05020  Prion disease
uar05022  Pathways of neurodegeneration - multiple diseases
uar05031  Amphetamine addiction
uar05152  Tuberculosis
uar05163  Human cytomegalovirus infection
uar05166  Human T-cell leukemia virus 1 infection
uar05167  Kaposi sarcoma-associated herpesvirus infection
uar05170  Human immunodeficiency virus 1 infection
uar05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uar05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123782828 (PPP3CB)
   04310 Wnt signaling pathway
    123782828 (PPP3CB)
   04370 VEGF signaling pathway
    123782828 (PPP3CB)
   04020 Calcium signaling pathway
    123782828 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    123782828 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    123782828 (PPP3CB)
   04218 Cellular senescence
    123782828 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    123782828 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    123782828 (PPP3CB)
   04660 T cell receptor signaling pathway
    123782828 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    123782828 (PPP3CB)
   04659 Th17 cell differentiation
    123782828 (PPP3CB)
   04662 B cell receptor signaling pathway
    123782828 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    123782828 (PPP3CB)
   04921 Oxytocin signaling pathway
    123782828 (PPP3CB)
   04924 Renin secretion
    123782828 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    123782828 (PPP3CB)
   04728 Dopaminergic synapse
    123782828 (PPP3CB)
   04720 Long-term potentiation
    123782828 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    123782828 (PPP3CB)
   04380 Osteoclast differentiation
    123782828 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123782828 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123782828 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    123782828 (PPP3CB)
   05163 Human cytomegalovirus infection
    123782828 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123782828 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    123782828 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123782828 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    123782828 (PPP3CB)
   05020 Prion disease
    123782828 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    123782828 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    123782828 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123782828 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:uar01009]
    123782828 (PPP3CB)
Enzymes [BR:uar01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     123782828 (PPP3CB)
Protein phosphatases and associated proteins [BR:uar01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     123782828 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 123782828
NCBI-ProteinID: XP_045639138
LinkDB
Position
Unknown
AA seq 537 aa
MNLKEKIFFFFVGVMKLEVVMWSCTKTKALSAVPFPPTHRLTSEEVFDMDGIPRVDVLKN
HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSP
ANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKI
KYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMC
DLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGY
RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMD
VFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDERLIYGNKKVGSAAARKEIIRN
KIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAI
RGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgaacctcaaggagaagatattttttttcttcgttggagtgatgaaattggaagtggta
atgtggagctgcactaagaccaaagccctctctgctgtacctttccccccgacacatcgc
ttgacatctgaagaagtatttgatatggatgggatacccagggttgatgttctgaagaac
cacttagtaaaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggt
gctgccatccttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgt
ggtgacatccatggccaattttttgatctgatgaaactttttgaagtaggaggatcacct
gctaatacacgatacctttttcttggtgattatgtggacagaggttattttagtatagag
tgtgtcttatatttatgggtcctgaagattctgtacccaagcacattatttcttctgaga
ggcaatcatgaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaatt
aaatattcagaaagagtctatgaagcttgtatggaagcttttgatagtctgcctcttgct
gcacttttaaatcaacaatttctttgtgttcatggtggactttcaccagaaatacacaca
ctggatgatattaggagattagatagattcaaagagccacctgcatttggaccaatgtgt
gacttgctatggtccgatccttctgaagattttggaaatgaaaaatcacaggaacatttt
agtcacaatacagttcgaggatgttcttatttttataactatccagcagtgtgtgaattt
ttgcaaaacaataatttgttatcgattattagagctcatgaagctcaagatgcaggctat
agaatgtacagaaaaagtcaaactacagggttcccttcattaataacaattttttcggca
cctaattacttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtg
atgaatattcgacagtttaactgttctccacatccttactggttgcccaattttatggat
gtcttcacatggtctttaccatttgttggagaaaaagtgacagaaatgttggtaaatgtt
ctgagtatttgctctgatgatgaactgatgactgaaggtgaagaccagtttgatgaacgg
ctcatatatggcaataaaaaagtaggttcagctgcagcccggaaagaaatcataagaaac
aaaattcgagcaattggcaagatggcacgggtcttctctgttctcagggaggagagtgaa
agcgtgctgacactcaagggcctgactcccacagggatgttgcctagtggagtgttggct
ggaggacggcagaccctgcaaagtgccacagttgaggctattgaggctgaaaaagcaata
cgaggattctctccaccacatagaatctgcagttttgaagaggcaaagggtttggatagg
atcaatgagagaatgccaccccggaaagatgctgtacagcaagatggtttcaattctctg
aacaccgcacatgccactgagaaccacgggactggcaaccatagtgcccagtga

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