Ursus americanus (American black bear): 123785662
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Entry
123785662 CDS
T07931
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar04620
Toll-like receptor signaling pathway
uar04621
NOD-like receptor signaling pathway
uar04622
RIG-I-like receptor signaling pathway
uar04623
Cytosolic DNA-sensing pathway
uar04625
C-type lectin receptor signaling pathway
uar04657
IL-17 signaling pathway
uar04936
Alcoholic liver disease
uar05160
Hepatitis C
uar05161
Hepatitis B
uar05162
Measles
uar05164
Influenza A
uar05165
Human papillomavirus infection
uar05167
Kaposi sarcoma-associated herpesvirus infection
uar05168
Herpes simplex virus 1 infection
uar05169
Epstein-Barr virus infection
uar05171
Coronavirus disease - COVID-19
uar05207
Chemical carcinogenesis - receptor activation
uar05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
123785662 (IKBKE)
04621 NOD-like receptor signaling pathway
123785662 (IKBKE)
04622 RIG-I-like receptor signaling pathway
123785662 (IKBKE)
04623 Cytosolic DNA-sensing pathway
123785662 (IKBKE)
04625 C-type lectin receptor signaling pathway
123785662 (IKBKE)
04657 IL-17 signaling pathway
123785662 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
123785662 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
123785662 (IKBKE)
05160 Hepatitis C
123785662 (IKBKE)
05171 Coronavirus disease - COVID-19
123785662 (IKBKE)
05164 Influenza A
123785662 (IKBKE)
05162 Measles
123785662 (IKBKE)
05168 Herpes simplex virus 1 infection
123785662 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
123785662 (IKBKE)
05169 Epstein-Barr virus infection
123785662 (IKBKE)
05165 Human papillomavirus infection
123785662 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123785662 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123785662 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123785662 (IKBKE)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
123785662 (IKBKE)
Protein kinases [BR:
uar01001
]
Serine/threonine kinases: Other
IKK family [OT]
123785662 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
APH
Motif
Other DBs
NCBI-GeneID:
123785662
NCBI-ProteinID:
XP_045643445
LinkDB
All DBs
Position
Unknown
AA seq
758 aa
AA seq
DB search
MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTASYLRPHEVQVREFEVLR
KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEEEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNIMRLMGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKTFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEMMYRITTE
KPAGAIAGTQRQENGPLEWSYSLPITCRLSTGLQTQLVPILANILEVEQAKCWGFDQFFA
ETSDILQRVVVHVFSLSQAVLHHVYIHAHNTIAIFLEAVYEQTQVAPQHQEYLFEGHLCV
LEPSLSAQHIAHTTSSSPLTLFSTASETPKGLAFRDPAQDIPKFFPKVDLQSDYTTSKSV
LGAGYQALWLAQTLLAGQELMLRGLHWFVEVLQAMGRRTLEVVRVALLFLSSSLGTERFS
SVSGTPEIEEVKRVTELKSRLRALAEALSRCSHRITETQSRLSNLSSELLKNRDQVHADR
SIQKIQCCLDKMNLIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSRLAKRLLKVFQEKCVQ
KYQTSLVTHGMWMREVHETRNRLRMVGCSVAAHNTEAQGVQESLSKILDRLSHQLLQDRA
KEAQVSPPPAAPYPSPALTDLVFHMRELCDEMKLLAFDLQDNNRIIEGGQASLGPWNWGH
ELGSQEQSLWLSPELQSTLRLRTHPHRIPFQQGENPAA
NT seq
2277 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcaccgccaactacctgtggcacacggacgacctgctgggccagggcgccact
gccagcgtgtacaaggcccggaacaagaaatccggggagctggttgccgtgaaggtcttc
aacacggccagctacctgcgcccgcacgaggtgcaggtgagggagttcgaggtcctgcga
aagctgaaccaccagaacatcgtcaagctcttcgcggtggaggagacagggggcagccgg
cagaaggtgctggtgatggagtactgctctagcgggagcctgctgagcgtgctcgagagc
cccgagaatgcctttgggctgcccgaggaggagtttctggtggtgctgcgctgtgtggtg
gctggcatgaaccacctgcgggagaatggcatcgtccaccgcgacatcaagcctgggaat
atcatgcgtctcatgggggaggaggggcagagcatctacaagctcacggacttcggggcc
gcccgggagctagacgatgacgagaagtttgtctctgtctatggcactgaggagtacctg
caccccgacatgtatgagagggctgtgcttcgcaagccccagcagaagacattcggggtg
actgtggatctctggagcattggggtcaccctgtaccacgccgccactggcagcctgccc
ttcatcccttttggtgggccacgacgcaacaaggagatgatgtaccggatcaccacggag
aagccggccggcgccatcgcaggcactcagaggcaggagaacgggcccctggagtggagc
tacagcctccccatcacctgccgcctgtccacggggctgcagacccagctggtgcccatc
ctggccaacatcctggaggtggagcaggccaagtgctggggcttcgaccagttctttgca
gagaccagtgacatcctgcagcgagtcgttgtgcacgtgttctccctgtcccaggccgtc
ctgcaccacgtctacatccacgcccacaacacgatagccatctttctggaggctgtgtat
gagcagacccaggtagccccccagcaccaggagtacctcttcgagggtcacctctgcgtc
cttgagcccagcctgtcagcacaacacatcgcccacacgacctcaagcagccccctgacg
ctgttcagcacagccagtgagacccccaaggggttggccttcagggacccggctcaggac
atccccaagttcttccccaaagtggacctgcagtcagattacaccacttccaagagtgtg
ttgggcgccggctaccaggccctgtggctggcgcagaccctgctggccgggcaggagctc
atgcttcgggggctgcactggtttgtggaggtgctccaggccatgggcaggcggacactg
gaggtcgtgcgggtggccctccttttcctcagcagcagcctaggcactgagaggttcagc
agtgtgtctgggacgcctgagatagaggaggtgaagagagtgaccgagctgaagtccagg
ctgcgggctctggcagaggccctctccagatgctcccacaggatcacagagacccagtca
cgcctgagcaacctgagctctgagctgctgaagaaccgggatcaggtacatgcggacaga
agcatccagaagattcagtgttgtttggacaagatgaacctcatctacaaacaattcaag
aaatccagaatgaggccagggcttggctacaacgaggagcagattcacaagctggataag
gtgaattttagtcgtctagccaagaggcttctgaaggtattccaggagaagtgtgtgcag
aagtaccagacatccctggtcacgcacggcatgtggatgagggaggtgcacgagaccagg
aaccgtctgcgcatggtcggctgttccgtggctgcccacaacacggaagcccagggagtc
caggagagcctcagcaagatccttgaccggttatctcaccagctccttcaggacagagca
aaggaggctcaggtctcaccacccccggcagccccctatcccagccctgcactgacggac
ctggttttccacatgagggaactctgcgatgagatgaagctgctggcctttgaccttcag
gacaacaaccgcatcattgaaggaggccaggccagtctgggaccctggaattggggccac
gagctggggagccaggagcagagcctgtggttgtccccagagttgcagagtaccctccgg
ctgaggacacatccccaccgcatcccattccagcaaggggagaatccagccgcttaa
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