Ursus americanus (American black bear): 123796968
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Entry
123796968 CDS
T07931
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
uar
Ursus americanus (American black bear)
Pathway
uar01521
EGFR tyrosine kinase inhibitor resistance
uar01522
Endocrine resistance
uar04012
ErbB signaling pathway
uar04015
Rap1 signaling pathway
uar04062
Chemokine signaling pathway
uar04137
Mitophagy - animal
uar04144
Endocytosis
uar04360
Axon guidance
uar04370
VEGF signaling pathway
uar04510
Focal adhesion
uar04520
Adherens junction
uar04530
Tight junction
uar04540
Gap junction
uar04611
Platelet activation
uar04613
Neutrophil extracellular trap formation
uar04625
C-type lectin receptor signaling pathway
uar04727
GABAergic synapse
uar04750
Inflammatory mediator regulation of TRP channels
uar04810
Regulation of actin cytoskeleton
uar04912
GnRH signaling pathway
uar04915
Estrogen signaling pathway
uar04917
Prolactin signaling pathway
uar04919
Thyroid hormone signaling pathway
uar04921
Oxytocin signaling pathway
uar04926
Relaxin signaling pathway
uar05100
Bacterial invasion of epithelial cells
uar05135
Yersinia infection
uar05152
Tuberculosis
uar05161
Hepatitis B
uar05163
Human cytomegalovirus infection
uar05167
Kaposi sarcoma-associated herpesvirus infection
uar05168
Herpes simplex virus 1 infection
uar05203
Viral carcinogenesis
uar05205
Proteoglycans in cancer
uar05207
Chemical carcinogenesis - receptor activation
uar05208
Chemical carcinogenesis - reactive oxygen species
uar05219
Bladder cancer
uar05417
Lipid and atherosclerosis
uar05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
uar00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123796968 (SRC)
04015 Rap1 signaling pathway
123796968 (SRC)
04370 VEGF signaling pathway
123796968 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
123796968 (SRC)
04137 Mitophagy - animal
123796968 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
123796968 (SRC)
04520 Adherens junction
123796968 (SRC)
04530 Tight junction
123796968 (SRC)
04540 Gap junction
123796968 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
123796968 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123796968 (SRC)
04613 Neutrophil extracellular trap formation
123796968 (SRC)
04625 C-type lectin receptor signaling pathway
123796968 (SRC)
04062 Chemokine signaling pathway
123796968 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
123796968 (SRC)
04915 Estrogen signaling pathway
123796968 (SRC)
04917 Prolactin signaling pathway
123796968 (SRC)
04921 Oxytocin signaling pathway
123796968 (SRC)
04926 Relaxin signaling pathway
123796968 (SRC)
04919 Thyroid hormone signaling pathway
123796968 (SRC)
09156 Nervous system
04727 GABAergic synapse
123796968 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123796968 (SRC)
09158 Development and regeneration
04360 Axon guidance
123796968 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
123796968 (SRC)
05207 Chemical carcinogenesis - receptor activation
123796968 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
123796968 (SRC)
05203 Viral carcinogenesis
123796968 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
123796968 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
123796968 (SRC)
05168 Herpes simplex virus 1 infection
123796968 (SRC)
05163 Human cytomegalovirus infection
123796968 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
123796968 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
123796968 (SRC)
05152 Tuberculosis
123796968 (SRC)
05100 Bacterial invasion of epithelial cells
123796968 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123796968 (SRC)
05418 Fluid shear stress and atherosclerosis
123796968 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123796968 (SRC)
01522 Endocrine resistance
123796968 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uar01001
]
123796968 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
uar04131
]
123796968 (SRC)
Enzymes [BR:
uar01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
123796968 (SRC)
Protein kinases [BR:
uar01001
]
Non-receptor tyrosine kinases
SRC family
123796968 (SRC)
Membrane trafficking [BR:
uar04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
123796968 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
123796968 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
123796968 (SRC)
Macropinocytosis
Kinases
123796968 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH3_10
ABC1
Haspin_kinase
SH3_3
Motif
Other DBs
NCBI-GeneID:
123796968
NCBI-ProteinID:
XP_045660540
LinkDB
All DBs
Position
Unknown
AA seq
536 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagccc
gctgagaacacccacggtggcggcgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccctagtacggccttcccctccgcagctgccgag
cccaagctgttcgggggcttcaactcgtcagacacagtcacctccccacagagggcgggg
ccgctggctggtggagtgaccacctttgtggccctctacgactatgagtctcggacagag
accgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacagagggtgac
tggtggctggcccactcgctcagcacgggacagacgggttacatccctagcaactatgtg
gcgccctccgactctatccaggccgaggagtggtactttggcaagatcaccagacgggag
tcggagcggttactgctcaatgcggagaacccgagagggaccttcctagtgcgagaaagt
gagaccacgaaaggtgcctactgcctctccgtgtctgatttcgacaacgccaagggcctc
aacgtgaagcactacaagatccgcaagctggacagcggcggcttctacatcacgtcccgc
acccagttcaacagtctgcagcagctggtggcctactactccaaacatgctgacggcctg
tgccaccgcctcaccactgtgtgccctacgtccaagccccagactcagggcctggccaag
gatgcctgggagatccctcgggagtccctgcggctggaggtcaagctgggccaaggctgt
ttcggagaggtgtggatggggacctggaatggaaccaccagggtggccatcaaaaccctg
aagccaggcacgatgtctccggaggccttcctgcaggaggcccaggtcatgaagaaactg
aggcacgagaagctggtgcagctgtatgcggtggtgtctgaggaacctatctacatcgtc
acggagtacatgagcaaggggagtctgctggactttctcaagggggagacgggcaagtac
ctgcggctgcctcagctggtggacatggctgctcagatcgcctcaggcatggcctacgtg
gaacggatgaactatgtccaccgggacctccgtgctgccaacatcctggttggagagaac
ctcgtgtgcaaagtggctgactttgggctggctcggctcatcgaagacaatgagtacacg
gcccggcaaggtgccaaattccccatcaagtggacagctcccgaagcggccctctacggc
cggttcaccatcaagtcagatgtatggtcctttgggatcctgctgacggagctcacaaca
aagggacgggtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcgg
ggctaccgaatgccctgcccgcccgagtgtcccgagtccctgcacgacctcatgtgccag
tgctggcggaaggagccggaggagcggcccaccttcgagtacctgcaggccttcctggaa
gactacttcacgtccaccgagccccagtaccagcctggagagaacctatag
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