KEGG   Ursus americanus (American black bear): 123796968
Entry
123796968         CDS       T07931                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
uar  Ursus americanus (American black bear)
Pathway
uar01521  EGFR tyrosine kinase inhibitor resistance
uar01522  Endocrine resistance
uar04012  ErbB signaling pathway
uar04015  Rap1 signaling pathway
uar04062  Chemokine signaling pathway
uar04137  Mitophagy - animal
uar04144  Endocytosis
uar04360  Axon guidance
uar04370  VEGF signaling pathway
uar04510  Focal adhesion
uar04520  Adherens junction
uar04530  Tight junction
uar04540  Gap junction
uar04611  Platelet activation
uar04613  Neutrophil extracellular trap formation
uar04625  C-type lectin receptor signaling pathway
uar04727  GABAergic synapse
uar04750  Inflammatory mediator regulation of TRP channels
uar04810  Regulation of actin cytoskeleton
uar04912  GnRH signaling pathway
uar04915  Estrogen signaling pathway
uar04917  Prolactin signaling pathway
uar04919  Thyroid hormone signaling pathway
uar04921  Oxytocin signaling pathway
uar04926  Relaxin signaling pathway
uar05100  Bacterial invasion of epithelial cells
uar05135  Yersinia infection
uar05152  Tuberculosis
uar05161  Hepatitis B
uar05163  Human cytomegalovirus infection
uar05167  Kaposi sarcoma-associated herpesvirus infection
uar05168  Herpes simplex virus 1 infection
uar05203  Viral carcinogenesis
uar05205  Proteoglycans in cancer
uar05207  Chemical carcinogenesis - receptor activation
uar05208  Chemical carcinogenesis - reactive oxygen species
uar05219  Bladder cancer
uar05417  Lipid and atherosclerosis
uar05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    123796968 (SRC)
   04015 Rap1 signaling pathway
    123796968 (SRC)
   04370 VEGF signaling pathway
    123796968 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    123796968 (SRC)
   04137 Mitophagy - animal
    123796968 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123796968 (SRC)
   04520 Adherens junction
    123796968 (SRC)
   04530 Tight junction
    123796968 (SRC)
   04540 Gap junction
    123796968 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    123796968 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    123796968 (SRC)
   04613 Neutrophil extracellular trap formation
    123796968 (SRC)
   04625 C-type lectin receptor signaling pathway
    123796968 (SRC)
   04062 Chemokine signaling pathway
    123796968 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123796968 (SRC)
   04915 Estrogen signaling pathway
    123796968 (SRC)
   04917 Prolactin signaling pathway
    123796968 (SRC)
   04921 Oxytocin signaling pathway
    123796968 (SRC)
   04926 Relaxin signaling pathway
    123796968 (SRC)
   04919 Thyroid hormone signaling pathway
    123796968 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    123796968 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123796968 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    123796968 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    123796968 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    123796968 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    123796968 (SRC)
   05203 Viral carcinogenesis
    123796968 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    123796968 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    123796968 (SRC)
   05168 Herpes simplex virus 1 infection
    123796968 (SRC)
   05163 Human cytomegalovirus infection
    123796968 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123796968 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    123796968 (SRC)
   05152 Tuberculosis
    123796968 (SRC)
   05100 Bacterial invasion of epithelial cells
    123796968 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123796968 (SRC)
   05418 Fluid shear stress and atherosclerosis
    123796968 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123796968 (SRC)
   01522 Endocrine resistance
    123796968 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uar01001]
    123796968 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:uar04131]
    123796968 (SRC)
Enzymes [BR:uar01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     123796968 (SRC)
Protein kinases [BR:uar01001]
 Non-receptor tyrosine kinases
  SRC family
   123796968 (SRC)
Membrane trafficking [BR:uar04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    123796968 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    123796968 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    123796968 (SRC)
  Macropinocytosis
   Kinases
    123796968 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH3_10 ABC1 Haspin_kinase SH3_3
Other DBs
NCBI-GeneID: 123796968
NCBI-ProteinID: XP_045660540
LinkDB
Position
Unknown
AA seq 536 aa
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1611 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagccc
gctgagaacacccacggtggcggcgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccctagtacggccttcccctccgcagctgccgag
cccaagctgttcgggggcttcaactcgtcagacacagtcacctccccacagagggcgggg
ccgctggctggtggagtgaccacctttgtggccctctacgactatgagtctcggacagag
accgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacagagggtgac
tggtggctggcccactcgctcagcacgggacagacgggttacatccctagcaactatgtg
gcgccctccgactctatccaggccgaggagtggtactttggcaagatcaccagacgggag
tcggagcggttactgctcaatgcggagaacccgagagggaccttcctagtgcgagaaagt
gagaccacgaaaggtgcctactgcctctccgtgtctgatttcgacaacgccaagggcctc
aacgtgaagcactacaagatccgcaagctggacagcggcggcttctacatcacgtcccgc
acccagttcaacagtctgcagcagctggtggcctactactccaaacatgctgacggcctg
tgccaccgcctcaccactgtgtgccctacgtccaagccccagactcagggcctggccaag
gatgcctgggagatccctcgggagtccctgcggctggaggtcaagctgggccaaggctgt
ttcggagaggtgtggatggggacctggaatggaaccaccagggtggccatcaaaaccctg
aagccaggcacgatgtctccggaggccttcctgcaggaggcccaggtcatgaagaaactg
aggcacgagaagctggtgcagctgtatgcggtggtgtctgaggaacctatctacatcgtc
acggagtacatgagcaaggggagtctgctggactttctcaagggggagacgggcaagtac
ctgcggctgcctcagctggtggacatggctgctcagatcgcctcaggcatggcctacgtg
gaacggatgaactatgtccaccgggacctccgtgctgccaacatcctggttggagagaac
ctcgtgtgcaaagtggctgactttgggctggctcggctcatcgaagacaatgagtacacg
gcccggcaaggtgccaaattccccatcaagtggacagctcccgaagcggccctctacggc
cggttcaccatcaagtcagatgtatggtcctttgggatcctgctgacggagctcacaaca
aagggacgggtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcgg
ggctaccgaatgccctgcccgcccgagtgtcccgagtccctgcacgacctcatgtgccag
tgctggcggaaggagccggaggagcggcccaccttcgagtacctgcaggccttcctggaa
gactacttcacgtccaccgagccccagtaccagcctggagagaacctatag

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