Ursus americanus (American black bear): 123803088 Help Entry 123803088         CDS       T07931                                  Symbol SPHK1 Name (RefSeq) sphingosine kinase 1 isoform X1   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism uar  Ursus americanus (American black bear) Pathway uar00600   Sphingolipid metabolism uar01100   Metabolic pathways uar04020   Calcium signaling pathway uar04071   Sphingolipid signaling pathway uar04072   Phospholipase D signaling pathway uar04148   Efferocytosis uar04370   VEGF signaling pathway uar04371   Apelin signaling pathway uar04666   Fc gamma R-mediated phagocytosis uar05152   Tuberculosis Module uar_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:uar00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     123803088 (SPHK1)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     123803088 (SPHK1)    04371 Apelin signaling pathway     123803088 (SPHK1)    04020 Calcium signaling pathway     123803088 (SPHK1)    04072 Phospholipase D signaling pathway     123803088 (SPHK1)    04071 Sphingolipid signaling pathway     123803088 (SPHK1)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     123803088 (SPHK1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     123803088 (SPHK1)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     123803088 (SPHK1) Enzymes [BR:uar01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      123803088 (SPHK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  123803088 NCBI-ProteinID:  XP_045670239 LinkDB All DBs Position Unknown AA seq 487 aa AA seqDB search MPERAGRRAWSEDLAGRSPPQGAAPDSASSVSSPSDPAAAGDDAGASTAPAPGGEGEPLS RHRDARLGSTDKELKAGATAAGSSATALGTPWQRELRVEVMDPAGGARSLLPRPCRVLVL LNPRGGKGKALQLFRSHVQPLLVQADVSFTLMLTERRNHARELVRVEELGRWDALVVMSG DGLMHEVVNGLMERPDWETAIRKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTL LLCRRLLAPMNLLSLRTASGLRLFSVLSLAWGFIADVDLESEKFRRLGEMRFTLGTFLRL AALRVYQGTLAYLPAERVVSQVPAPPAVERQDQQGPTDAHLVPLEEPVPPHWTVVPEQDF VLVLALLHSHLGSEMFAAPMGRCAAGTMHLFYVRAGVSRAMLLRLFLAMEKGRHMDYDCP YLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAVQGQVHPDYVWMVSGCMEPPPSQKPQQG PPPGEPL NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgcccgagcgcgcgggtcgccgcgcgtggtccgaggatctagctgggcgctccccacct cagggggccgctccggactccgccagctctgtctcctctccctcagatcccgcagccgca ggggatgacgcgggtgcctccacggccccggctccgggcggggagggcgagcccctcagc cggcaccgcgacgcccgcctgggcagcaccgataaggagctgaaagcaggagccaccgcc gcgggcagctccgcgacagcgctggggacgccctggcagcgggagctgcgagtcgaggtt atggatccagcgggcggcgccaggagcctgctgccccggccctgccgcgtgctggtcctg ttaaacccgcgcggaggcaagggcaaggcgctgcagctcttccgcagccacgtgcagcct ctgctggtccaagccgatgtctccttcacgctcatgctaactgagcggcggaaccatgca cgggagctggtgcgggttgaggagctggggcgctgggatgcgctggtggtcatgtctgga gacgggctgatgcatgaggtggtgaacgggctcatggagcggccagactgggagactgcc atccggaagcccctgtgtagcctcccagctggctctggcaatgcactggcagcttctttg aaccattatgctggctacgagcaggtgactaatgaggacctcctgaccaactgcacgctg ctgctgtgtcgccgcctcctggcgcccatgaacctgctgtcactgaggacagcctcaggg ctgcgcctcttctccgtgctgagcctggcttggggcttcatcgccgacgtggatctggag agtgagaagtttcggcgtctaggggagatgcgcttcactctgggcaccttcctgcgcctg gcagccctgcgagtctaccagggcacgctggcctacctccctgcagaaagggtggtctcc caggtgcccgccccccctgccgtggagcgccaggatcagcagggtcccacggatgcccac cttgtacccctggaggagccggtgcccccgcactggactgtggtcccggagcaggacttc gtgctcgtgctggcgctgctgcactcccacctgggcagcgagatgtttgcggcccccatg ggccgatgtgcggccggcaccatgcatctcttctatgtgcgggcaggcgtgtctcgggcc atgctgctgcgcctcttcctggccatggagaaggggaggcacatggactatgactgtccc tacttggtgtacgtgcctgtggttgccttccgcctggagcccaaggacggaaagggtgtg tttgctgtggatggcgagttgatggtcagcgaggctgtgcagggccaggtgcacccagac tacgtctggatggtcagtggctgcatggagcccccacccagccagaagcctcagcaggga ccacctccaggcgagcccttatga

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