Ursus maritimus (polar bear): 103663941
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Entry
103663941 CDS
T03271
Symbol
NRG2
Name
(RefSeq) pro-neuregulin-2, membrane-bound isoform isoform X1
KO
K05456
neuregulin 2
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr04012
ErbB signaling pathway
umr05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103663941 (NRG2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
103663941 (NRG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103663941 (NRG2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
umr04052
]
103663941 (NRG2)
Cytokines and neuropeptides [BR:
umr04052
]
Cytokines
Growth factors (RTK binding)
103663941 (NRG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Neuregulin
I-set
Ig_3
ig
EGF
DUF6377
EGF_2
Motif
Other DBs
NCBI-GeneID:
103663941
NCBI-ProteinID:
XP_040478290
UniProt:
A0A8M1F7Y2
LinkDB
All DBs
Position
Unknown
AA seq
838 aa
AA seq
DB search
MRQVCCSALPPPPLEKARCSSYSDSSSSSGSSSSSSSERSSSSSSSSGSSSESSSRSSSS
SNSSISRPAAPPEPRPPQQPQPRSPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLA
CYSPSLKSVQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRS
GGLQREQVISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPIDTNGKNLKKEVGKILCT
DCATRPKLKKMKSQTGQVGERQSLKCEAAAGNPQPRSRDIRIKYGNGRKNSRLQFNKVKV
EDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVCYYIE
GINQLSCKCPNGFFGQRCLEKLPLRLYMPDPKQKAEELYQKRVLTITGICVALLVVGIVC
VVAYCKTKKQRKQMHNQLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKNVPATDH
VIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGIMLSSVG
TSKCNSPACVEARARRAAAYSLEERRRAAVPPYHDSVDSLRDSPHSERYVSALTTPARLS
PVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPISYRLAEQQPLLRQPAPPGPGPGPGAD
MQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRA
RGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADGALAAES
TPFLGLRAAHDALRSDSPPLCLAADSRTYYSLDSHSTRASSRHSRGPPPRGKQDSAPL
NT seq
2517 nt
NT seq
+upstream
nt +downstream
nt
atgcggcaggtttgctgctcagcgctgccgccgccgccactggagaaggctcggtgcagc
agctacagcgacagcagcagcagcagcggcagcagcagcagcagcagcagcgagaggagc
agcagcagcagcagcagcagcggcagcagcagcgagagcagcagcaggagcagcagcagc
agcaacagcagcatctcccgtcccgctgcgcccccagagccgcggccgccgcaacagccg
cagccccgcagccccgcagcccggagagccgccgcccgctctcgagccgcagccgccggc
ggcatgaggcgcgacccggcccccggcttctccatgctgctcttcggtgtgtcgctcgcc
tgctactcgcctagcctcaagtcggtgcaggaccaggcatacaaggcaccggtggtggtg
gagggcaaggtacaggggctggccccagccggcggctccagctccaacagcacccgcgag
ccgcccgcctcgggtcgggtggcgctggtgaaggtgctggacaagtggccgctccggagc
ggggggctgcagcgcgagcaggtgatcagcgtgggctcctgtgcgccgctcgaaaggaac
cagcgctacatctttttcctggagcccacggagcagcccttagtctttaagacggccttt
gcccccatcgacaccaacggcaaaaacctcaagaaagaggtgggcaagatcctgtgcacg
gactgcgccacccggcccaagctgaagaagatgaagagccagacgggacaggtgggtgag
aggcagtccctgaagtgcgaggcagcggcgggcaaccctcagccccgcagccgcgacatt
cgcatcaagtacggcaacggcagaaagaactcgcgactacagttcaacaaggtgaaggtg
gaggatgctggggagtacgtctgcgaggctgagaacatcctgggcaaggacacggtccgg
ggccggctccatgtcaacagcgtgagtaccaccctgtcatcctggtcggggcacgcccgg
aagtgcaacgagacagccaagtcctattgtgtcaatggaggcgtctgctactacatcgag
ggcatcaaccagctctcctgcaaatgtccaaacggattcttcggacagagatgtttggag
aaactgcctttgcgattgtacatgccagatcctaagcaaaaagccgaggagctgtaccag
aagagggtcctgactatcaccggcatctgcgtggctctgctcgtagtgggcattgtctgc
gtggtcgcctactgcaagaccaagaaacagcggaaacagatgcacaatcagctccggcag
aacatgtgcccggcccaccagaaccggagcttggccaacgggcccagccacccccggctg
gaccccgaggagatccagatggcagattacatctccaagaatgtgccggccacggaccat
gtcatccggagggaaaccgagaccaccttctctgggagccactcctgttctccttctcac
cactgttccacggctacacccacctccagccacaggcatgagagccacacgtggagcctg
gaacgttctgaaagcctgacctctgactcccagtcgggcatcatgctgtcatcggtgggc
accagcaagtgcaacagcccggcgtgtgtggaggcccgggcgcggcgggcagcggcctac
agcctggaagagcggcgcagggctgccgtgccaccttaccacgactccgtagactccctg
cgtgactccccacacagcgagaggtacgtgtcggcactgaccacgcccgcgcgcctctct
cccgtggacttccactattcgctggccacgcaggtgccgacttttgagatcacgtccccc
aactcggcgcacgcagtgtcgctgccgccggcggcgcccatcagctaccgcctggcggag
caacagccgctcctgcggcagccggcgccccctggcccggggcccgggcccggcgcggac
atgcagcgcagctacgacagctactactaccccgcggcgggaccggggccgcggcgcggg
gcttgcgcgctgggcggcagcctgggcagcctgcccgccagccccttccgcatcccggag
gacgacgagtacgagaccacgcaggagtgcgcgcccccgcccccgccgcgcccgcgcgcc
cgcggcgcgtcccgcaggacgtcggcggggccccggcgctggcgccgctcgcgcctcaac
gggctggcggcgcagcgcgcacgcgcggcgcgggactcgctgtcgctgagcagcggctcg
gggggcggctcggcctctgcctcggacgacgacgcggacggggcgctggcggccgagagc
acgcctttcctcggcctgcgcgcggcgcacgatgcgctgcgctcggactcgccgccgctg
tgcctggcggccgacagcaggacttactactccctggacagtcacagcacgcgggccagc
agcagacacagccgcgggccgcccccgcggggcaagcaggactcggcgcccctctag
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