Ursus maritimus (polar bear): 103668547 Help Entry 103668547         CDS       T03271                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism umr  Ursus maritimus (polar bear) Pathway umr00230   Purine metabolism umr01100   Metabolic pathways umr01522   Endocrine resistance umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04022   cGMP-PKG signaling pathway umr04024   cAMP signaling pathway umr04062   Chemokine signaling pathway umr04072   Phospholipase D signaling pathway umr04114   Oocyte meiosis umr04211   Longevity regulating pathway umr04213   Longevity regulating pathway - multiple species umr04261   Adrenergic signaling in cardiomyocytes umr04270   Vascular smooth muscle contraction umr04371   Apelin signaling pathway umr04540   Gap junction umr04611   Platelet activation umr04713   Circadian entrainment umr04714   Thermogenesis umr04723   Retrograde endocannabinoid signaling umr04724   Glutamatergic synapse umr04725   Cholinergic synapse umr04727   GABAergic synapse umr04750   Inflammatory mediator regulation of TRP channels umr04911   Insulin secretion umr04912   GnRH signaling pathway umr04913   Ovarian steroidogenesis umr04914   Progesterone-mediated oocyte maturation umr04915   Estrogen signaling pathway umr04916   Melanogenesis umr04918   Thyroid hormone synthesis umr04921   Oxytocin signaling pathway umr04923   Regulation of lipolysis in adipocytes umr04925   Aldosterone synthesis and secretion umr04926   Relaxin signaling pathway umr04927   Cortisol synthesis and secretion umr04928   Parathyroid hormone synthesis, secretion and action umr04934   Cushing syndrome umr04935   Growth hormone synthesis, secretion and action umr04961   Endocrine and other factor-regulated calcium reabsorption umr04962   Vasopressin-regulated water reabsorption umr04970   Salivary secretion umr04971   Gastric acid secretion umr04972   Pancreatic secretion umr04976   Bile secretion umr05032   Morphine addiction umr05163   Human cytomegalovirus infection umr05166   Human T-cell leukemia virus 1 infection umr05200   Pathways in cancer umr05207   Chemical carcinogenesis - receptor activation umr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103668547 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103668547 (ADCY9)    04371 Apelin signaling pathway     103668547 (ADCY9)    04020 Calcium signaling pathway     103668547 (ADCY9)    04072 Phospholipase D signaling pathway     103668547 (ADCY9)    04024 cAMP signaling pathway     103668547 (ADCY9)    04022 cGMP-PKG signaling pathway     103668547 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103668547 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     103668547 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103668547 (ADCY9)    04062 Chemokine signaling pathway     103668547 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     103668547 (ADCY9)    04923 Regulation of lipolysis in adipocytes     103668547 (ADCY9)    04912 GnRH signaling pathway     103668547 (ADCY9)    04913 Ovarian steroidogenesis     103668547 (ADCY9)    04915 Estrogen signaling pathway     103668547 (ADCY9)    04914 Progesterone-mediated oocyte maturation     103668547 (ADCY9)    04921 Oxytocin signaling pathway     103668547 (ADCY9)    04926 Relaxin signaling pathway     103668547 (ADCY9)    04935 Growth hormone synthesis, secretion and action     103668547 (ADCY9)    04918 Thyroid hormone synthesis     103668547 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     103668547 (ADCY9)    04916 Melanogenesis     103668547 (ADCY9)    04925 Aldosterone synthesis and secretion     103668547 (ADCY9)    04927 Cortisol synthesis and secretion     103668547 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103668547 (ADCY9)    04270 Vascular smooth muscle contraction     103668547 (ADCY9)   09154 Digestive system    04970 Salivary secretion     103668547 (ADCY9)    04971 Gastric acid secretion     103668547 (ADCY9)    04972 Pancreatic secretion     103668547 (ADCY9)    04976 Bile secretion     103668547 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     103668547 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     103668547 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     103668547 (ADCY9)    04727 GABAergic synapse     103668547 (ADCY9)    04725 Cholinergic synapse     103668547 (ADCY9)    04723 Retrograde endocannabinoid signaling     103668547 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103668547 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     103668547 (ADCY9)    04213 Longevity regulating pathway - multiple species     103668547 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     103668547 (ADCY9)    04714 Thermogenesis     103668547 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103668547 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     103668547 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103668547 (ADCY9)    05163 Human cytomegalovirus infection     103668547 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     103668547 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103668547 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103668547 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103668547 (ADCY9) Enzymes [BR:umr01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103668547 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  103668547 NCBI-ProteinID:  XP_008695054 UniProt:  A0A384CKP8 LinkDB All DBs Position Unknown AA seq 1352 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGVPRRVGAGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHVRSKLIVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLAAQFQVLTPLSGRVDSSNHTLAAKPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVVYSVLFETFGYHFRDKDCFPPPGAGAPHWELLSRALLHLCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQSVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVS SGPRRQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQEEHKN STKAPGAPNSKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAATTAPPPAALAVFSAALLLEMLSLVVSIR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHFTVFMGS AVLITVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSIVISHLDAGQNFSSEG NPCNSSLPRDGGTASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKI QSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKEC YRVLNELIGDFDELLSRPGYSSIEKIKTIGATYMAASGLNGAQCQDGSHPQEHLQVLFEF AKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDSTG VECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDSGAVPQHQLSISPD IRVQVDGSIGRSPTDEIANLVPSVQNADKMSLGSENNVQAKDIHLSSKRPWKEPFKAEER CRFGKAIEKSDCEEAGMEEASELTRLNVSKSV NT seq 4059 nt NT seq  +upstreamnt  +downstreamnt atggcttccccaccccaccagcagctgctgcagcaccacagcaccgaggtgagttgtgac tccagcggagacagcaacagcgtgagggtcaaaattaaccccaagcagctgtcctccaac agccaccccaagcactgcaagtacagcatctcctccagctgtagcagctctggggactca gggggtgtcccccggagagtgggcgctggaggccgcctgcgcaggcagaagaagctgccc cagctgttcgagagggcctccagccgatggtgggaccccaagttcgactccgtgaacctg gaggaggcttgcatggagcgctgcttcccgcagacccagcgccgcttccgatatgcgctc ttctacatcggcttcgcctgccttctgtggagcatctattttggggtccacgtgaggtcc aaactgattgtcatggtagccccagctctgtgcttcctcgtagtgtgtgtgggctttttt ctgtttaccttcaccaagctgtatgcccggcattacgtgtggacctctctggttctcacc ctcctggtgttcgccctgaccctggctgcccagtttcaggttttgacgcctctctcagga cgtgttgacagctccaatcataccctcgcagccaagcccacagacacttgcttatctcaa gtggggagcttttccatgtgcatcgaagtgctctttttactctacacggtcatgcactta cctttgtacttgagcttgtttttgggagtggtctattctgttctctttgagacctttggc tatcatttccgagacaaagactgctttcccccacctggagcaggggcgccacactgggag ttgctgagccgagccctgctccacctctgcattcatgccattgggatccacctatttatc atgtcccaggtgagatctcggagcacctttctcaaggtgggacagtcaattatgcatgga aaggatctggaagtggaaaaagccctgaaagagaggatgattcattctgtgatgccgaga atcatagctgatgacctgatgaaacagggggatgaggagagcgagaattctgtcaaaagg cacgcgacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctata gcattccgccctttcaaaatgcagcagatagaagaagtcagtattttatttgcagatatc gtgggcttcacaaagatgagtgccaataagtctgctcacgccctggtgggtctcctcaac gatctgtttggtcgctttgaccggttgtgtgaagagaccaagtgtgagaaaattagtacc ctgggagactgctactattgtgtggcggggtgtccggagccccgggccgaccatgcctac tgctgcattgagatgggcttgggcatgatcagagctatcgagcaattctgccaggagaag aaagagatggtgaacatgcgtgtcggggttcacacggggactgtcttgtgcggcattttg ggcatgaggaggttcaaattcgatgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggcgggcaaggttcacatttctgaggccacagcaaaatacctagat gatcggtacgaaatggaagatgggaaagttactgaacgccttggccagagcgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcagctgctcagaggccttgctttctggctttgaggtcattgacggctcacgggtgtcc tcaggtcctaggagacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgtccttcatgcggaatcacgtttgcccccaaa tcggaagctggtgcagaaggaggagcggtccaaaatggctgtcaagaggagcataaaaac agcaccaaggctcctggagcaccgaattccaaaactcagaatggacttctgagccctccc caagaggaaaagctcaccaacagtcagacctccctgtgtgagatcttacaggaaaaggga aggtgggcaggagtgagcttggaccagtcagctctccttccgctgagattcaagaacatc cgggagaaaacagatgcccattttgtcgatgttatcaaagaagacagcctgatgaaagat tattttttcaagccacccatcaatcagttcagcttgaacttcctggatcaggagctagag cgatcctataggaccagctaccaagaagaggttataaagaattctcccgtgaagactttt gccagtgccaccttcagctccctcctggatgtgtttctttcgacgacagtgtttctaatt ctctctatcacctgcttcctgaagtacggggctgccaccacggctcccccgcctgccgcc ctggcagtcttcagcgccgccctgctgctggagatgctgagccttgtggtctccatcagg atggtgtttttcctggaggatgtgatggcctgtacgaagcgcctgctggagtggatagcc ggctggctcccgcgccatttcattggggccatcctggtgtcactccctgctcttgcagtc tattcacatgtcacctctgaatttgagacaaacatacacttcaccgtgtttatgggctca gccgtcctgatcaccgtcgtgcactactgtaacttctgccagctcagctcctggatgagg tcctccttagccacagtcgtcggggctgggcccctgctcctgctctatgtctccctgtgc cctgacagttccatagtaatttcacaccttgatgcaggacagaatttcagttccgagggg aatccgtgcaatagttccttgccacgtgatggcggaacggccagcctgattggccaggag gtgattcttgtcttctttctcctgctcctgttggtctggttcctgaatcgagaattcgag gtcagctaccgcctgcactaccatggggacgtggaggcggaccttcaccgcaccaagatc cagagcatgagggaccaagctgactggctgctgagaaacatcatcccctaccacgtggcc gagcagctgaaggtctcacagacctactccaagaaccacgacagcggaggcgtcatcttc gccagcatcgtcaacttcagtgagttctacgaggagaactacgaggggggcaaggagtgc taccgggtcctcaacgagctcatcggggacttcgacgagctcctgagcaggccgggctac agcagcatcgagaagatcaagaccattggggccacgtacatggctgcatcgggtctgaac ggcgcccagtgccaggacggcagccacccgcaggagcacctgcaggtcctgtttgagttc gccaaggagatgatgcgtgtggtggacgacttcaacagcaacatgctgtggttcaacttt aagctcagggtcggcttcaaccatgggccgctcacagcgggggtcatcggcaccaccaag ctgctgtatgacatctggggcgacactgtcaacatcgccagcaggatggacagcacaggg gtggagtgccgcatccaggtgagcgaggagagctaccgcgtcctgagcaagatgggctac gacttcgactaccgggggacagtgaacgtgaagggcaagggccagatgaagacctacctg tacccaaagtgcatggacagcggggccgtgccacagcaccagctgtccatctccccggac atccgagtccaggtggacggcagcattgggcggtctcccacggatgagatcgccaacctg gtgccttctgtacagaatgcagacaagatgtctctgggttccgaaaacaacgttcaggcc aaggacattcacctgtcctctaagaggccgtggaaagagcccttcaaagccgaagaaagg tgtcgatttggcaaagccatagagaaaagtgactgtgaagaagctggcatggaggaagcc agcgagctcaccaggctcaatgtttccaagagcgtgtga

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