Ursus maritimus (polar bear): 103673532 Help Entry 103673532         CDS       T03271                                  Symbol PLA2G4D Name (RefSeq) cytosolic phospholipase A2 delta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism umr  Ursus maritimus (polar bear) Pathway umr00564   Glycerophospholipid metabolism umr00565   Ether lipid metabolism umr00590   Arachidonic acid metabolism umr00591   Linoleic acid metabolism umr00592   alpha-Linolenic acid metabolism umr01100   Metabolic pathways umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04072   Phospholipase D signaling pathway umr04217   Necroptosis umr04270   Vascular smooth muscle contraction umr04370   VEGF signaling pathway umr04611   Platelet activation umr04664   Fc epsilon RI signaling pathway umr04666   Fc gamma R-mediated phagocytosis umr04724   Glutamatergic synapse umr04726   Serotonergic synapse umr04730   Long-term depression umr04750   Inflammatory mediator regulation of TRP channels umr04912   GnRH signaling pathway umr04913   Ovarian steroidogenesis umr04921   Oxytocin signaling pathway umr05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:umr00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     103673532 (PLA2G4D)    00565 Ether lipid metabolism     103673532 (PLA2G4D)    00590 Arachidonic acid metabolism     103673532 (PLA2G4D)    00591 Linoleic acid metabolism     103673532 (PLA2G4D)    00592 alpha-Linolenic acid metabolism     103673532 (PLA2G4D)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103673532 (PLA2G4D)    04014 Ras signaling pathway     103673532 (PLA2G4D)    04370 VEGF signaling pathway     103673532 (PLA2G4D)    04072 Phospholipase D signaling pathway     103673532 (PLA2G4D)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     103673532 (PLA2G4D)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103673532 (PLA2G4D)    04664 Fc epsilon RI signaling pathway     103673532 (PLA2G4D)    04666 Fc gamma R-mediated phagocytosis     103673532 (PLA2G4D)   09152 Endocrine system    04912 GnRH signaling pathway     103673532 (PLA2G4D)    04913 Ovarian steroidogenesis     103673532 (PLA2G4D)    04921 Oxytocin signaling pathway     103673532 (PLA2G4D)   09153 Circulatory system    04270 Vascular smooth muscle contraction     103673532 (PLA2G4D)   09156 Nervous system    04724 Glutamatergic synapse     103673532 (PLA2G4D)    04726 Serotonergic synapse     103673532 (PLA2G4D)    04730 Long-term depression     103673532 (PLA2G4D)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103673532 (PLA2G4D)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     103673532 (PLA2G4D) Enzymes [BR:umr01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      103673532 (PLA2G4D) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  103673532 NCBI-ProteinID:  XP_008700537 UniProt:  A0A384D0C9 LinkDB All DBs Position Unknown AA seq 817 aa AA seqDB search MERLTTRGPPGRPHQGEASACWRLTVRVLEARNLGWTDLLSEADPYVTLQLPTVPGTKFK TKTITNSSHPVWNETFSFLIQSQVKNVLELNVYDEDSVTEDDACFKFLYDVSEVLPGKLL RKTFSLQPQGQEELDVEFLLEKTSDCPENLITNNVLVARELSCLDVHLDHTESVATVTDQ AKLELELVLTGSYENTQTSALGPASAFRFHYMAAQDAELSARVRSSESNGWNSDKTAGHL TVPLRSLAMGKEVTINIPATNTPGVRLQLETESCPKKLAVHLGFDLCAEEQAFLSRRKQV VAKALKQTLQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGI SGSTWTMAHLYGDPEWSQKDLEGPIKYAREHLTKSKMEAFSPERLASYHQELELRAEQGH PTTFVDLWALVLESMLHGQVMDQKLSEQRAALEQGQNPLPLYLSLNVKENNLETLDFKEW VEFSPYEVGFLKYGAFVPAELFGSEFFMGRLMRRLPESRICFLEGIWSNIFSLNLLDVWY GLISSDDTRKQHIKDKIRSLEESPASSKTSSWLEASWLQPGTALARAFKGLLTDRPLHQH SCNFLRGLQLHQDYRSQKDFSTWADCQLDSTASQLTPQEPQLCLVDAGYFLNTSCPSMFR SGRRLDLILAFDYSLPSPFEALQQTEVYCRARGLPFPRVEPSPQDQRQPTECHLFSDPSC PDAPVLLHFPLVNASFRDHSAPGVRRSPAELPAGQVDLTGTASPYSLFNMTYKEEDFDRL LQLSDYNVRNSQGAILQALRTAVKHRALGARPPAAQN NT seq 2454 nt NT seq  +upstreamnt  +downstreamnt atggaaagactgacaactaggggaccacctggccgccctcaccagggggaggcctctgct tgctggcggctcactgtgagggttctggaggcacggaacctgggctggactgacctgttg agtgaggcagacccctatgtgaccctacagctgcccaccgtccctggaacaaagtttaag accaaaacaatcaccaactccagtcatcctgtgtggaatgagaccttcagtttcctaatc cagagtcaggtcaagaatgtcctggagctaaatgtctatgatgaggactcagtcacggaa gatgatgcctgcttcaagtttctctatgacgtctcagaagtcctccccggcaagctgctc cggaagaccttctccctgcagccccagggacaggaggagctggacgtggagttcctgctg gaaaaaacgtcagactgtccagaaaacctcatcaccaacaacgtccttgtggcccgagag ctgtcatgcctggatgtccatctggaccacacggagagcgtagccaccgtcacagatcag gccaagctggagctggagctcgtgctgacggggtcctatgaaaacacacagacatctgcg ctggggccagcctctgccttccgcttccattacatggcagcccaagacgcagagctgagt gcgcgtgtgaggagctctgaaagcaatggctggaattccgacaagacagctgggcacctc actgtgcccctgaggtcactggccatgggaaaggaggtgacgattaacattcccgctaca aataccccaggagtgaggctgcagctcgagactgagagctgccctaagaagctggctgtg cacctgggctttgatctgtgcgcagaggagcaggccttcctgagcaggaggaaacaggtg gtcgccaaggctctcaagcagaccctgcagctggacagagacctacaggaggatgaggtc cctgtggtgggtatcatggccacaggaggaggtgcccgggccatgacctctctctacggc cacctgttggccctgcagaagctgggcctcctggactgtgtgacctacttcagcggcatc tcaggctctacatggacaatggcccacctctacggggaccctgagtggtcacagaaggac ctcgaaggacccatcaaatatgccagggaacacctgaccaagagcaagatggaggccttc tccccagagcgcctagcgagctaccaccaggagctggaactgcgggcggagcagggccac cccacgacttttgttgacctgtgggctctcgtgctggagtccatgctgcacggccaggtg atggatcagaagctgtcggaacagagagcagcactggagcagggccagaaccctctgccc ctctacttgagcctcaatgtcaaagagaacaatctggagaccctcgacttcaaggagtgg gtggagttttccccctatgaggtcgggttcctgaagtatggagccttcgtccctgccgag ctcttcggctccgagttcttcatgggccggctgatgaggaggctccctgagtcccggatc tgctttctggaaggtatctggagcaacattttctccctgaacttgctggatgtctggtac ggcctcatcagctctgatgacacccgcaagcagcacatcaaggacaagatcaggagcctg gaggagtctcctgcctcctcgaagacctcctcatggttggaggcctcatggctgcaaccc gggacagcactggccagggcgtttaagggcttgctgacggacaggccactccaccagcac agctgcaacttcctccggggcctccagctgcaccaggactaccgtagccagaaagacttc tccacctgggcagactgccagctagactccaccgctagccagctgactcctcaggagccc cagctctgcctggtagatgccggctacttcctcaacaccagctgtccctccatgttccgg tcaggccgcaggctggacctcatacttgccttcgactactccctaccctcgccctttgag gcactgcagcagactgaggtgtactgccgggcccggggactgccattccctcgagtggag cccagccctcaggaccaacgccagccaacagagtgccacctcttctcagacccctcctgc cccgatgccccggtcctgctgcacttcccactggtcaacgcctccttcagggaccactca gcccccggtgtccggcgcagccccgcagagctcccagccggccaggtggatctcactggg accgcctccccctactccctgttcaacatgacctacaaggaggaagactttgatcgtctg ctgcagcttagtgactataacgtacggaacagccagggcgccattctgcaggccttgagg actgccgtgaagcaccgggccctgggcgccaggcctccagcggcacagaattga

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