KEGG   Ursus maritimus (polar bear): 103675680
Entry
103675680         CDS       T03271                                 
Symbol
ITGA5
Name
(RefSeq) integrin alpha-5 isoform X1
  KO
K06484  integrin alpha 5
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr03266  Virion - Herpesvirus
umr04145  Phagosome
umr04151  PI3K-Akt signaling pathway
umr04510  Focal adhesion
umr04512  ECM-receptor interaction
umr04640  Hematopoietic cell lineage
umr04810  Regulation of actin cytoskeleton
umr04820  Cytoskeleton in muscle cells
umr05100  Bacterial invasion of epithelial cells
umr05133  Pertussis
umr05135  Yersinia infection
umr05165  Human papillomavirus infection
umr05168  Herpes simplex virus 1 infection
umr05205  Proteoglycans in cancer
umr05206  MicroRNAs in cancer
umr05410  Hypertrophic cardiomyopathy
umr05412  Arrhythmogenic right ventricular cardiomyopathy
umr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:umr00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    103675680 (ITGA5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    103675680 (ITGA5)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    103675680 (ITGA5)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    103675680 (ITGA5)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103675680 (ITGA5)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    103675680 (ITGA5)
   04810 Regulation of actin cytoskeleton
    103675680 (ITGA5)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    103675680 (ITGA5)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    103675680 (ITGA5)
   05205 Proteoglycans in cancer
    103675680 (ITGA5)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    103675680 (ITGA5)
   05165 Human papillomavirus infection
    103675680 (ITGA5)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    103675680 (ITGA5)
   05133 Pertussis
    103675680 (ITGA5)
   05100 Bacterial invasion of epithelial cells
    103675680 (ITGA5)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103675680 (ITGA5)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    103675680 (ITGA5)
   05414 Dilated cardiomyopathy
    103675680 (ITGA5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103675680 (ITGA5)
   04515 Cell adhesion molecules [BR:umr04515]
    103675680 (ITGA5)
   04090 CD molecules [BR:umr04090]
    103675680 (ITGA5)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   103675680 (ITGA5)
Cell adhesion molecules [BR:umr04515]
 Integrins
  Integrin alpha subunits
   103675680 (ITGA5)
CD molecules [BR:umr04090]
 Proteins
  103675680 (ITGA5)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_1 Integrin_A_Ig_2 FG-GAP FG-GAP_3 Integrin_alpha
Other DBs
NCBI-GeneID: 103675680
NCBI-ProteinID: XP_040498518
UniProt: A0A8M1GS21
LinkDB
Position
Unknown
AA seq 1055 aa
MGSRAPGFPLHAAQLRWGPRRRPPLPLLLLPPLLLLLPPPPRVGGFNLDAEAPAVLSGPP
GSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPWGASRVHCTPIEFDSK
GSRILELLVSGPEGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTC
YLSTDNFTRILEYAPCRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSA
TQEQIAESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKG
NLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDINGDGLDDLLVGAPLLMERTAD
GRPQEVGRVYVYLQHPAGMEPTPALTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPF
GGETQQGVVFIFPGGPGGLGSKPSQVLLPLWAAGHTPDFFGSALRGGRDLDGNGYPDLIV
GSFGVDKAVVYRGRPIVSTSASLAIFPAMFNPEERSCSLEGSPVACINLSFCLNASGKHV
PDSIGFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREECREMKIYLRNESE
FRDKLSPIHIALNFSLDPQAPVDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQ
LEVFGEQNHVYLGDKNSLNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRNPGNFSSL
SCDYSAVNQSRLLVCDLGNPMKAGASIWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQ
SEVVSFRLSVEAHAQVSLNGVSKPEAVLFPVSDWHPRDQPQEEGDVGPAVHHVYELINQG
PSSISRGMLELSCPRTLEGQQLFYMTRVTGLGNCTASHPPNPQNLELDPEGSQHHQLQRR
EAPGRSPASPGPQVLKCPEVECFRLRCELGPLHRQESRSLQLHFRVWAKTFLQREHQPFS
LQCDAVYEALKMPYRIPPQQLPRKELQVATAVQWTKAEGSHGVPLWIIILAVLVGLLLLG
LLIYVLYKLGFFKRSLPYGTAMEKAQLKPPATSDA
NT seq 3168 nt   +upstreamnt  +downstreamnt
atggggagccgggcaccagggttccctctccacgccgcgcaactgcgctggggaccccgg
cgccgacccccgctgccgctgctgctgctgccgccgctgctgctgctgctgccgccgcca
cccagggtcgggggcttcaatttggacgccgaggccccagctgtactctctgggcccccg
ggctccttcttcggcttctcggtggagttttaccggccgggaacagacggggtcagcgtg
ctggtgggagcgcccaaggctaacaccagccagccaggagtgctgcagggtggtgctgtc
tacctctgtccctggggcgccagccgggtacactgcacacccattgaatttgacagtaaa
ggctctcggatcctggagttgttggtgtccggcccagagggagaggagcctgtggagtac
aagtccttgcagtggttcggagcgacagtccgagcccacggctcctccatcttggcctgt
gctcctctgtatagctggcgcacggagaaggagccgctgagtgaccccgtgggcacctgc
tacctctccacagacaacttcacccgaattctggagtatgcgccttgccgctcagatttc
agctgggcagcaggacagggttactgccaaggcggcttcagtgctgagttcaccaagact
ggacgtgtggtcctcggtggaccagggagctatttctggcaaggccagatcctgtctgcc
acccaggaacagattgcagaatcctactaccctgagtatctgatcaacctggtgcagggg
cagctgcagacccgccaggccagttccatctacgatgacagctacctgggatactctgtg
gctgtgggcgaattcagtggtgacgacacagaagactttgttgctggcgtgcccaaaggg
aacctcacctatggttatgtcaccatccttaatggctcagacatccgatccctctacaac
ttctcaggggaacagatggcctcctacttcggctatgcagtggctgccacagacatcaac
ggggacgggctggatgacttgctggtgggggctcctctgctcatggagcggactgcggac
gggcggcctcaggaggtgggcagggtgtacgtctatctgcagcacccagctggaatggag
cccacacccgccctgaccctcaccggccatgatgagtttggccgatttggcagctccctg
acccccctgggggacctggaccaggacggctacaatgatgtagccattggagctcccttt
ggtggagagacccagcagggagtggtgtttatattccctgggggccctggggggctgggc
tctaagccatcccaggttctgctgcccctgtgggcggctggccacacgccggacttcttt
ggctctgcgctccgaggaggccgagacctggatggcaatggataccctgatctgatcgtg
gggtccttcggtgtggacaaggctgtggtgtataggggccgccccattgtctctaccagt
gcctccctcgccatcttccctgccatgttcaacccagaggagcgcagctgcagcttggag
gggagccctgtggcttgcatcaaccttagcttctgcctcaatgcttctggaaaacacgtt
cctgactccattggcttcacggtggagctccagttggactggcagaagcagaagggggga
gtgcggcgggcactgttcctggcctccagacaggcgaccctgacccagaccctgctcatc
cagaatggggctcgggaggagtgcagagagatgaagatctacctcaggaatgagtcagag
ttccgagataagctctccccgattcatatcgccctcaacttctcgctggacccccaagcc
cctgtggacagccatggcctccggccagtcctacattaccagagcaagagccgcatagag
gacaaggctcagatcttgctggactgtggagaagacaacatctgtgtgccagacctacag
ctggaagtgtttggggagcagaaccacgtgtacctgggcgacaagaactccctgaaccta
actttccacgcccagaatgtgggtgagggcggtgcctatgaggccgagcttcgggtcaca
gcccctccagaggccgagtattccgggctcgtcagaaacccagggaacttctccagcctg
agctgtgactactctgctgtgaaccagagccgcctgctggtgtgtgacctgggcaacccc
atgaaggcaggagccagtatctggggtggccttcggttcacagtccctcacctccgggac
acaaagaaaaccatccagtttgacttccagattctcagcaagaatctcaacaactcacaa
agcgaagtggtttccttccggctctcagtggaggctcacgcccaggtctcccttaatggt
gtctccaagcctgaggccgtgctattccctgtgagtgactggcatccccgagaccagcct
caggaagagggagacgtgggccctgctgtccaccacgtctatgagctcatcaaccagggc
cccagctccattagccggggcatgctggagctcagctgtccccggactctggaaggtcag
cagcttttctacatgaccagggtgacaggacttggcaactgcaccgccagtcaccccccc
aacccacagaacctggagttggatccggaaggttcccagcaccaccagctacaaagacgg
gaagctccaggccgcagcccagcctccccaggacctcaggtcctgaaatgccccgaggtg
gagtgtttcaggctgcgttgtgagcttgggccactgcaccggcaagagagccgaagtctg
caactgcatttccgagtctgggccaagaccttcctgcaacgggaacaccagccatttagc
ctgcagtgtgatgccgtgtatgaagccctgaagatgccctaccgaatcccgccgcagcaa
cttccccgaaaggaacttcaggtggccacggcggtgcagtggaccaaggcagaaggcagc
cacggcgtcccgctctggatcattatcctagccgtcctcgttggcctcctgctcctcggg
ctgctcatctatgtcctctacaagctcggattcttcaaacgctctctcccatacggcacc
gccatggaaaaagctcaactcaagccaccagccacctctgatgcctga

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