Vicugna pacos (alpaca): 102537928
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Entry
102537928 CDS
T08098
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
vpc
Vicugna pacos (alpaca)
Pathway
vpc00020
Citrate cycle (TCA cycle)
vpc00190
Oxidative phosphorylation
vpc01100
Metabolic pathways
vpc01200
Carbon metabolism
vpc04714
Thermogenesis
vpc04932
Non-alcoholic fatty liver disease
vpc05010
Alzheimer disease
vpc05012
Parkinson disease
vpc05014
Amyotrophic lateral sclerosis
vpc05016
Huntington disease
vpc05020
Prion disease
vpc05022
Pathways of neurodegeneration - multiple diseases
vpc05208
Chemical carcinogenesis - reactive oxygen species
vpc05415
Diabetic cardiomyopathy
Module
vpc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
vpc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
vpc_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
vpc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102537928 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
102537928 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
102537928 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102537928 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
102537928 (SDHA)
05012 Parkinson disease
102537928 (SDHA)
05014 Amyotrophic lateral sclerosis
102537928 (SDHA)
05016 Huntington disease
102537928 (SDHA)
05020 Prion disease
102537928 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
102537928 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102537928 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102537928 (SDHA)
Enzymes [BR:
vpc01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
102537928 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
102537928
NCBI-ProteinID:
XP_015106997
UniProt:
A0A6J0B4Q3
LinkDB
All DBs
Position
3
AA seq
665 aa
AA seq
DB search
MSGVRAVSRLLRAQRLALSSGQQPAALQTGSRSFHFTIDGNKRSSAKVSDAISTQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECRGVIALCI
EDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLKHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKI
SQLYRDLQHLRTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKE
RVDEYDYSKPIQGQQQKPFEQHWRKHTLSYVDIKTGKVSLEYRPVIDRTLNEADCATVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggcgtacgcgcggtgtcgcggctgttgcgcgcccagcgcttggcgctgagctcc
gggcagcagccagcagcattgcagacaggatcccgcagtttccacttcaccattgatggc
aataagaggtcgtctgccaaagtttcagatgcaatttctacgcagtacccagtagtggat
catgaatttgatgcagtggtggtcggcgctggaggggctggcctacgagctgcatttggt
ctttctgaggcagggtttaacacggcctgtgttacgaagctctttcctaccaggtcacac
actgtcgcagcccaggggggcatcaacgctgccctggggaacatggaggaggacaactgg
aggtggcacttctatgacactgtgaagggctccgactggctgggggaccaggatgccatc
cactacatgacggagcaggcccccgcctccgtggtggagctggagaactacggcatgccg
ttcagcagaactgaggatgggagaatctaccagcgcgcctttggaggacagagcctgaag
ttcgggaaaggcgggcaggcccatcggtgctgctgtgtggctgaccgcactggccactca
ctgctgcacacgttgtatggaaggtctctgcgatacgataccagctattttgtggagtat
tttgccttggatctcctgatggaagatggggagtgtcgtggagttattgccctgtgcata
gaggacgggtccatccaccgcatcagagcaaagaacactgttgtggccacgggaggctac
gggcgcacctacttcagctgcacgtctgcccacaccagcaccggggatggcactgccatg
atcaccagggcaggccttccctgccaggacctggagttcgttcagttccaccccacaggc
atatacggtgctggctgtctcatcacggaagggtgccgtggagagggcggcatcctcatt
aacagtcaaggcgaaaggttcatggagcggtacgcccccgtcgcaaaggacctggcatcc
agggacgttgtgtcccggtccatgactctggaaatccgtgaaggaagaggctgtggccct
gagaaggaccacgtctacctgcagctgcatcacctgcccccagagcagctggcaatgcgc
ctgcctggcatctcagaaacggccatgatcttcgcaggcgtggatgtcaccaaggagccg
atccccgtgctccccaccgtgcactataacatgggcggcatccccacgaactacaagggg
caggttctgaagcacgtgaatggccaagatcagatcgtgccaggcctatacgcgtgtggg
gaggccgcctgcgcctctgtgcatggcgccaaccgtctgggggccaactcactcctagac
ctggtggtctttggccgagcgtgcgccctgagcatcgcagagtcctgcagacccggagat
aaggttccctcgattaaaccgaatgctggggaagaatctgtcatgaatcttgacaaattg
agatttgctaatggaagcataagaacatcggaactgcgactcaacatgcagaagtcgatg
cagagccatgctgcagtgttccgtgttgggagcgtgctgcaggagggctgtgagaagatc
agccagctctaccgcgacctgcagcacctgaggacatttgaccggggaatggtttggaac
actgacctggtggagaccctggagctgcagaacctgatgctctgtgccctgcagaccatt
tacggagcagaggcccggaaggagtcacggggcgctcatgccagggaggatttcaaggag
cgggttgatgagtacgattactccaagcccatccaggggcagcagcagaagccgtttgag
cagcactggaggaagcacacgctttcgtacgttgacatcaagacagggaaggtctcgctg
gaatacagacctgtcatcgacagaacgttgaacgaggctgactgcgccactgttccccca
gccatccgctcctactga
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