Vulpes vulpes (red fox): 112907887 Help Entry 112907887         CDS       T05911                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism vvp  Vulpes vulpes (red fox) Pathway vvp01521   EGFR tyrosine kinase inhibitor resistance vvp04151   PI3K-Akt signaling pathway vvp04217   Necroptosis vvp04380   Osteoclast differentiation vvp04550   Signaling pathways regulating pluripotency of stem cells vvp04620   Toll-like receptor signaling pathway vvp04621   NOD-like receptor signaling pathway vvp04630   JAK-STAT signaling pathway vvp04658   Th1 and Th2 cell differentiation vvp04659   Th17 cell differentiation vvp05140   Leishmaniasis vvp05145   Toxoplasmosis vvp05152   Tuberculosis vvp05160   Hepatitis C vvp05161   Hepatitis B vvp05162   Measles vvp05163   Human cytomegalovirus infection vvp05164   Influenza A vvp05165   Human papillomavirus infection vvp05166   Human T-cell leukemia virus 1 infection vvp05167   Kaposi sarcoma-associated herpesvirus infection vvp05168   Herpes simplex virus 1 infection vvp05169   Epstein-Barr virus infection vvp05171   Coronavirus disease - COVID-19 vvp05200   Pathways in cancer vvp05203   Viral carcinogenesis vvp05212   Pancreatic cancer vvp05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:vvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     112907887 (JAK1)    04151 PI3K-Akt signaling pathway     112907887 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     112907887 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     112907887 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     112907887 (JAK1)    04621 NOD-like receptor signaling pathway     112907887 (JAK1)    04658 Th1 and Th2 cell differentiation     112907887 (JAK1)    04659 Th17 cell differentiation     112907887 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     112907887 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112907887 (JAK1)    05203 Viral carcinogenesis     112907887 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     112907887 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     112907887 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     112907887 (JAK1)    05161 Hepatitis B     112907887 (JAK1)    05160 Hepatitis C     112907887 (JAK1)    05171 Coronavirus disease - COVID-19     112907887 (JAK1)    05164 Influenza A     112907887 (JAK1)    05162 Measles     112907887 (JAK1)    05168 Herpes simplex virus 1 infection     112907887 (JAK1)    05163 Human cytomegalovirus infection     112907887 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     112907887 (JAK1)    05169 Epstein-Barr virus infection     112907887 (JAK1)    05165 Human papillomavirus infection     112907887 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     112907887 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     112907887 (JAK1)    05140 Leishmaniasis     112907887 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     112907887 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:vvp01001]     112907887 (JAK1) Enzymes [BR:vvp01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      112907887 (JAK1) Protein kinases [BR:vvp01001]  Non-receptor tyrosine kinases   JAK family [OT]    112907887 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  112907887 NCBI-ProteinID:  XP_025839006 UniProt:  A0A3Q7RA95 LinkDB All DBs Position Unknown AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGLEVLFYLSDREPLRLGSGEYTAEEL CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITIDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFHPNDSGNILYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEMLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPHCPEEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagactgaggtgaatctggaggcccctgaaccagggttggaagtgctcttc tatctttctgatagggagcccctccggctgggcagcggagagtacacagcagaggagcta tgcatcagggccgcgcaggaatgctgtatctctccactttgtcacaacctctttgccctg tatgatgagaacaccaagctctggtatgctccgaatcgcaccatcaccattgatgacaag acatcgctccggctccactaccggatgaggttctatttcaccaactggcatgggactaat gataatgagcagtctgtatggcgacattccccaaagaagcagaaaaatggctatgagaaa aaaaaagttccagatgctacccctcttcttgacgccagttctttggagtatctctttgct cagggacaatatgatttggtcaaatgcctggctcccattcgagaccccaagactgagcag gatgggcacgatattgagaatgagtgtctgggaatggctgtcctggccatctcccactat gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctataagcgatat attccagagacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctgaaggaatttaataacaagactatttgtgacagtagt gtatctactcatgacctaaaggtgaaatatctggctaccttggaaactttgacaaagcat tatggtgctgaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat tggtttcatccgaacgacagtggaaacattctctactatgaagtgatggtaactggaaat cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa ctcaaacggaaaaaactggaaaataaacacaagaaggacgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttacttccctgaaatcacacacattgtaataaaggagtct gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcatcccatgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagatgcccat cattacctctgcactgatgtggctcccccattgatcgtccacaacatacagaatggttgt cacggtccaatctgcacagaatatgccatcaataagttgcggcaagaaggaagcgaggaa gggatgtatgtgctgaggtggagctgtaccgacttcgacaatattctcatgactgtcacc tgctttgaaaaatctgagatgctgggtggccagaaacagttcaagaattttcagattgag gtgcagaagggccgctatagcctgcacggctcagaccgcagcttccccagcctaggggac ctgatgagccacctcaagaagcagatcctgcgtacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaatctgctggtggctactaagaaagcc caagagtggcagccagtctaccccatgagccagctgagttttgaccggatcctcaagaag gatattgtgcaaggcgagcaccttgggagaggcacacggacacacatctactctggtact ctggtggattataaggacgatgaaggaacctctgaagaaaagagaataaaagtcatcctc aaagtcttagaccccagccacagggacatttctctggctttctttgaggcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtg gagaatatcatggtggaagagtttgtggaggggggacctctagatctcttcatgcaccgg aaaagtgatgtcctcaccacaccgtggaagttcaaagttgccaaacagctggccagtgcc ctgagttacttggaggataaagacctagttcatggaaatgtgtgcactaaaaaccttctc ctggcccgtgagggcattgacagtgagtgcggcccgttcatcaagctcagtgaccctggc atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccatggattgctcct gagtgtgttgaagactccaagaacctgagtgtggctgctgataaatggagctttggaacc acattgtgggaaatctgctacaatggcgagatccctctgaaagacaagaccctgattgag aaagagagattctacgaaagccggtgccggccagtgacaccatcctgtaaggagctggct gatcttatgacccgctgcatgaactatgaccccaaccagagacccttcttccgagccatc atgagagacatcaataaactggaagagcagaatccagacattgtttccgaaagaaagccg gcaaccgaagtggatcccacacattttgaaaagcggttcttgaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggataatact ggggagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat ctgaagaaggaaatcgaaattctaaggaacctttatcatgagaacattgtgaagtacaaa ggcatctgtacagaagacggaggaaatggtattaagctcatcatggaatttctgccttca ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacaacagtta aaatatgccgttcagatttgtaaggggatggactatttaggttctcggcaatatgttcac cgggacttagcagcaaggaatgtccttgttgagagtgaacaccaagtgaaaattggagac tttggtttgaccaaagcaattgaaactgacaaggagtactacacagtcaaggatgatcgg gacagccctgtgttttggtatgctcctgaatgtttaattcaatgtaaattttatatcgcc tctgatgtctggtcgtttggagtgaccctgcatgagttgcttacttactgtgactcagat tccagccccatggcgttgtttctgaaaatgataggcccaactcatggccagatgacagta acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacctcactgtcca gaagaggtttatcaacttatgagaaaatgctgggaattccagccatctaatcggacaact tttcagaaccttattgaaggatttgaagcacttttaaaataa

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