Vulpes vulpes (red fox): 112919530 Help Entry 112919530         CDS       T05911                                  Symbol SYNE1 Name (RefSeq) nesprin-1   KO K19326   nesprin-1 Organism vvp  Vulpes vulpes (red fox) Pathway vvp04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:vvp00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     112919530 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:vvp03036]     112919530 (SYNE1) Chromosome and associated proteins [BR:vvp03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     112919530 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin CH KASH Bromo_TP Motif Other DBs NCBI-GeneID:  112919530 NCBI-ProteinID:  XP_025853801 UniProt:  A0A3Q7SF06 LinkDB All DBs Position Unknown AA seq 8828 aa AA seqDB search MAASRTTSQSPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPLVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSGSTSSVDSMVSAETASPPSKRKVA TKIQGNAKKALLKWVQYTVAKQTGIEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGR SNQENLEEAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNTGTDGQ EIDEILPGFPSFANSIQNFKREDRLILKETKVWIEQFERDLTRAQMTESNLQDKYQSFKH FRVQYEIKRKQIEHLIQPVHRDGKLSLDQALVKQSWDRVSSRLFDWHIQLDKSLPAPLGT IGAWLYRAEVALREEITIQQVHEETANTIQRKREQHKDLLQNTDAHKRAFHEIYRTRSVN GIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRR ESVELLLQNYISFIENTKFFEQYEVTYQILKQTAEMYIQADGSVEEAENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVIANWDRYGNTVASLQAWLEDAEKMLNQTEHAKKDFFRNLPHW IQQHAAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADELDRMKKEY TDCVTALSDFAMGAHKKLSEPLEVSFLNVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLI TKESSQEEANEMFATMSGLKEQLTKVKDCYSPLLYESQQLLIPLEELEKQMTFFYDSVGK INEILTVLEHEAQSSAVFKQKQQELSACQESCKKTMTQIEKGSQNVQKFMTLSSVLKHFD QTKLHRQIADAHGAFQNMMKKIGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEK GNPEDLLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQG EAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLVPQEGSEKIIKEHRIFFSDKGPHHV CEKRLQLIEELCLKLPGRDPVRNTPETCHVTLKELRAAIDTTYMKLVEDPDKWKDYTSRI SQFSSWISAKETELKGFKNEPIDTANHGKVKHAVEEIRNDVTTKGETLNWLKSRLKVLIE VSSENEAQKQGDELAKLSGSFKALVALLSEVEKMLSNFGDCVQYKEIVKSSLEELISGSK EIQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIQQAQQGEGGLPGQVREE LRKLESTLDNMEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSYSSLE SLSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPKNKQLLQQQAKSIKEQVKKLEDT LEEDIKTMEMVKNKWDHFGNNFETLSIWITEKEKELNTLETSSSAMDMQINQIKVIIQEI QSKLSSITELEESAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQ QQKFEENLRKIQKSVSEFEDKLADPVKICSSATETYKVLQEHMDLCQTLEALSSTVATTS ANAQKVANRGSCVQEAAALQQRYQEMQSQAKERQTALEKLLAHWQRLEKELSTFLTWLER CEAITSSPEMDISSDRVKVESELQSIQALQNEVVSQASVYSNLLQLKESLFSVASKDDVK MMKLHLEQLDERWRDLPQIISKRIAFLQSVVAEHQQFDELLLSLSVWIKLFLSELQSTSE ISITDHQAAFTRHKDHAAEVESKKGELQSLQDHLVKLGALVRAESLPLLQGKAEDCFQLF EEASQVVERRQLALAQLAEFLQSHVSLSGVLHRLRHTVEATNSMNRKQTDLLEKDLNHAI QDAKSLESVAISLDSVLAKAQYHLKSGSSEQRTSCRTTADHLCSELERIQNLLGIKQSEA DALAVLKKAFQDQKEELLKSIEDIEERTDKERLKELTRQALQQRLRVFNQLEDELNSHEH ELCWLKDKAKQIAQKDVAFASEVDREVNRLEVTWNDTKKLIHENQGQCCGLIDLMREYQN LKSAVSKVLENASNVIATRTTIKDQEDLKWALSKHETAKNEMCNKQKELDNFTSKGKQLL FELKKIHSSDFILVKTDMESTVDRWLDISEKIEENMDRLRVSLTIWADVLSSKDEIDGWC NSSVPRLAESISNLNNSLRAEEFLKEFESEVKNKALRLEELHCKVNDLKELTKNPETPPD LQFVEADLRQKLEHAKEITEEAKGTLKDFTAQSTQVEKSINDITSWLTKVEESLMNCAQT ETWEGLKKVKEIQKELQSQQSNISSTQENLNSLCRKYHSVELESLGSALTGLIKNQEAVS QLCSKTQASLQDSLEKHFNESMQEFQEWFSGIKAAAKESSDRTGDSKVLEAKLHHLQNIL DSISDGQSKLDAVTQEGQTLYAHVSKQIVGSIQEKITKANEEFQAFLKQCLKDKQTLQDC ALELGSFEDQHRKLNLWIHEMDERLSTENLGESKQHIPEKKNEVHKVEMFLGELLAARES LDKLSQRGQLLSEEGHGAGKEGRLCSQLLTNYQNLLRMTKEKLRSCQVALQEHEALEEAL QSMWSWVKAIQDRLAAAESTIGSKDTLEKRLLQIQDILLMKGEGEVKLNMAIGKGEQALR SSNKQGQKVIQTQLQTLKDVWADIMSSSIHAQSTLESVISKWNDYLEWKNQLEQWMESVD QKVEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHAGALQHLTSKSRELYQKTENESFKETA QEELKTQFNDIITVSKEKMRKAEEIVKDHLMYLDAVQEFTDWLHSAKEELHRWSDMSGDS SATQKKLSKIKELMDSREIGASRLSRVELLAPTVKQNTSASGCELVDTEMQALRADWKQW EDSVVQTQTSLENLVSQMALSEQEFSGQVAQLEQALEQFSALLTTWAQQLALLEGKNTDK EIVECWQKGQEILDALQKAEPKTEDLKSQLNELCRFSRDLSTYSGKVSSLIKEYNCLCLQ ASKGCQNREQILQQRFRRAFKDFQQWLVNAKITTAKCFDIPQNINEVSTNLQKIQEFLSE SENGQHKLNMMLSKGELLGTLLTKEKADGIQAKVVTAKEDWKNFHSNLHQKESALENLKI QMKDFEVSAEPVQDWLSKTEKLVQESSNRLYDLPAKRREQQKLQSVLEEINCYEPQLNRL REKAQQLWEGQAASKSFMHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQ DWLTDAVHMLDSYCHPTSDKSVLDSRMLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSP EGIPAIQQQLQSVKDMWASLSSAAIRCKSQLEGALSKWTSYQDDVRQFSGWMDSMEASLN ESERQYAELREKTSALGKAKLLSEEVLSYSSLLETIELKGAGMTEHYVTQLEFQDLQERY RAIKERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDRHSVLEGDAHTHETTLR DLQELQVRCAEGQALLNSVLHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLTETRTQF NNVVNKLRLMEQKYQQIDEWLKTLENKVKVRTGRQSNRAAKEIQLHQMKKWHEEVTAYKD EVEEVGARAQEMLDENHVSSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESELS LNSYSDWYTSTHKNFKNVATKIDRVDKVMMGKKMKMLEGLLKDMEKGHSLLKSTREKGER ALKYLEDSEAETLRNEIHEHVEQLKELTSTVRKEHMTLEKGLLLAKEFSDKYKALTQWIS EYQEILHTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSVKSVREKGEALLELVQDVTLK DEIDKLQSDYKDLCDAGKEHVCSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLMET SSLETITQQLAHHKAMMEEIAGFEDRLNNLKIKGDNLISQCADHLQAKLKQNVHAHLQGT SDSYSAICSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLTAIQPDLKPSQLPPLSRAEAV KQVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWG EIKHMKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQCKQASMTAIT ERVNKLTKKQESPEHKEISHLNDQWLDLCLQSNNLCLQREEDLQRTRDYHDCMNVVEVFL EKFTTEWDNLARSDAESTAVHLEALKKLALALQDRKQAIEDLKDQKQKMIEHLNLDDKEL VKEQTSHLEQRWFQLEDLVKRKIQVSVTNLEELNVVRSRFQELMEWAEEQQPNISEALKQ SPPPDVAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQIIQKALSDAQSH VNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQV KTCKSAQASLKTYQNEVTGLWAQGRELMKGATEQEKSEVLGKLQELQSVYDTVLQKCSHR LQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESAELHTQLAKYQHILEQSP EYENLLLTLQRTGQAILPSLNEVDHSYLNEKLNALPLQFNVVVALAKDKFYKVQEAILAR KEYASLIELTAQSLSELEDQFLKMNKVPTDLIVEEALSLQDGCRALLREVSGLGEAVDEL NQKKESFRSTGQPWQPDKMLHLVTLYHRLKRQAEQRVNLLEDTTSAYQEHEKMCHQLEKQ LEAVKTEQSKVNEETLPAEEKLKMYHSLAGSLQDSEIILKRVTVHLEDLVPHLDPLAYEK AKQQIQSWQEELKLLTSAIGATVTECESRMVQSIDFQTELSRSLDWLRSVKAELSGPVCL ELSLQDIQEEIRKIQIHQEEVQSSLRIMNALSNKEKEKFTKAKELISADLQHTLAELSEL DGDIQEALRTRQAALTQIYGQCQRYYQVFQAANDWLEDAHEMLQLAGNGIDVESAEENLK SHMEFFSTEDQFHRNLEELQGLVASLDPLIKPTGKEDLAQKMASLEDKSQRIIQDSHAQL DLLQRCAAQWQDYQKAREEVIELMNDAEKKLSEFSLSKTSSSHEAEEKLSEHKSLVSVVN SFHEKVVALEDKTLQLEKTGNDASKAAISRSMTTVWQRWTRLRAVAQDQEKILEDAVDEW KSFNNKVKKATEIIDQLQDKLPGSSAEKASKAELLTLLDFHDTLILELEQQQLALGLLRQ QALSMLQDGATKSPGEEPSIVQEITAMQDRCLNMQEKVKSNGKVVKQELKEREVVETQIN SVKSWVQETKEYLGNPTIEIDAQLEELQILLTEATNRRQNIEKMTEEQKNKYLGLYSILP SEVSLQLAEVALDLGTIHDQIQDKVREVEQSKAMSQEFSRQIQKIAKDLTTILSKLRAKT DNLAQAKSDQKVLGEELDGCNLKLMELDAAVQKFSEQNGQLGKPLAKKIGKLSELHQQTI RQAENRLSKLSQAASHLEEYNEMLEFILKWIEKAKVLVHGKITWNSANQLREQYVLHQTM LEESEEIHSNLEAMIVKLQYLASVYSTEKMSQQVAELGRESEELRQMIKIRMHNLQDAAK DMKKFETELKNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQIC QSALRIPEDVVTSLPLCHAALHLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLRE LIEGAHREIEDTPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHA TMLLTVTEVEGLAEGTEDLDRELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSE ISSPPACRSPSPVANADASVNQDIAYYQALSAERLQTDAARIHPSTLPSQEFYEPGLEPS ATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESLEH GRSPESQMAEHQALMDEILMLQDEISELQSSLAEELVSESPESDPAEQLALQSTLTVLAE RMSTIKMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDHWLLSTKATLDTALGT AKEPMDMEAQLVDCQNMLLEIEQKVVALSELSVHNDNLLLEGKAHTKEEAEQLAIKLRVL KGSLLELQRALHDKQLNIQGTAQEKEESHVDLTASQSPGVQEWLAQARTTWTHQRQSSLQ QQKELEQELAEQKSLLRSVASRGEEILTQHSAAETSGGAGEKPDVLSQELGMEGEKSAAE DQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQTQDKSAVT SLLDGLNQVFEEVSSQSGGKKRQNIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEET EACLFNQETLAKDIKEMSEEMDKNRNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVV NQRCHQMKERLQQILNFQNDLKVLCTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDG LKELDAGIIELKRRGDKLQIEQPSMQELSKLQDMYDELMMTIGSRRSGLNQNLALKSQYE RALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKII SFAVPQETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDYQELSRQLEVVESSI PSVGLVEESEDRLIDRIALYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLEGQLNQL GEHWLNNTNKVSKELHRLETVLKHWTRYQSESVELIHWLQSAKDRLEFWTQQSVTVPQEL EMVRDHLNAFLEFSKEVDAKSSLKSSVLSTGNQLLRLKKVDTAALRSELSHIDSQWTDLL TNIPTVQEKLHQLQMDKLPSRHAISEVMTWISLMENVIQKDEENIQNSVGYKAIHEYLQK YKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTE KIQLLEGLLESWSEYENNVQSLKTWYETQENRLKQQHRIGDQASVQNAMKDCQDLEDLVK AKEKEVERIEQSGLALIQNKKEEVSGIVMSTLRELNQTWANLDHMVGQLKILLKSVFDQW NNHKVAFDEINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQEKNLQRFGS ITNQLLKECHPPVTETLTNTLKDVNMRWNNLLEEISEQLHSSKALLQLWQRYKDYSQQCA STVQQQEDRTNELLKAATNKDIADDEAATWIQDCNDLLKGLGIVKDSLFVLHELGEQLKQ QVDASAASAIQSDQLSLSQHLCALEQALCKQQTTLQVGVLDYETFTKSLEALEAWIVEAE DILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQN LNRRWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLE QQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQ QRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPVSALGSVPIPLQQARTLFDEVQFKEK VFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTEIQEKWKSASVRLEEQKKKLAFLL KDWENCENGIADSLEKLRTFKKKLSQPLPDHHEELHAEQMRCKELENVAGSWTDDMAQLT LLKDTLCAYISADDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKEL CEWLTQMESKVSQNGDILIEDMIEKLKKDYQEEIAVAQENKIQLQQMGERLARASHESKA SEIEYKLGKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPI VYDSCDSDEIQKKLTEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQA TRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKISERTAAFPSSSGVLY TVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRRDNL QKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAF QQEISLNHNKIEHIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIR LPLPDDEHDLSDRELELDDSAALSDLHWRDTSADSVLSPQPSSNPSLSLVQPLRSERSGR DTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGQDDKDFYLRGAVGLSDVMIPES PEAYVKLTESAIRNTSGPPSALESQIRQLDKALDESRFQMQQTENIIRSKTPTGPELDSS YRGYMKLLGECSGSIDSVKRLEHKLREEEENFPGFVNLNSTETQTAGVIDRWELIQAQAL SKELRMKQNLQKWQQFNSDLNNIWTWLGETEEELEQLQRLELSTDIQAIELQIKKLKELQ KAVDHRKALILSINLCSSEFTQTDSEKSQDLQDRLSQMNGRWDHVCSLLEEWRGLLQDAL MQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSNQDAETLQDHHKQLMQIRHELLESQLKV ASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSSQQDL SSWSSADELDTSGSVSPTSGRSTPNRQRTPRGKCSLSQPGPSVNSPHSRSIKGGSDSSLS EPQPARSGRAFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLR YTNGPPPL NT seq 26487 nt NT seq  +upstreamnt  +downstreamnt atggcagcttccaggacgacctcacagtctcctcgggacattgccaatgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgtacttttacaaaatggatcaactctcat ctggccaagcggaaacccccactggtggtagatgatctttttgaagacatgaaagatggt gttaagctgcttgcacttctggaggttctgtccgggcagaaattgccttgtgaacaagga cgccgtatgaagcggatccatgctgttgctaatattggcacagcactcaagttccttgaa ggaaggaagtccatgtacagaggatcaccgattaaattagtcaacattaactccactgat atagctgatggccgaccatcaatagttcttggattgatgtggaccattattctatatttc cagattgaggagttgaccagcaacctgccacagctgcagtctctgtctggcagcacatcc tctgtggatagcatggttagtgctgagactgccagccccccaagtaaacggaaagtggcc accaagattcaaggaaatgctaagaaggctttattaaagtgggttcagtacacagtagcc aagcagacgggaatagaagtaaaggactttgggcggagttggagaagtggggttgccttc cattctgtcatccatgccattcgaccagaactagtggacttggagaaagtgaaaggaaga tctaaccaggaaaacctggaggaggctttcactattgctgaaacagaactaggaatcccc agactgttggatcctgaagatgttgatgtggataaaccagatgagaagtctattatgacc tatgtagcccaatttctgaagcattaccctgacatccacaacacaggcactgatgggcaa gaaattgatgaaatacttccaggttttccatcttttgcaaattctatccaaaattttaag agagaagacaggctaattttgaaggaaacaaaagtttggatagaacaatttgaaagagat ttgacaagggcacagatgacagaatcaaatttgcaagataaatatcagtcatttaagcac ttcagagttcagtatgaaataaaaaggaaacagattgaacatttaatacaaccagtacat agagatggtaaactgtcacttgaccaagcattggtaaaacaatcctgggacagagtgtcc tccaggctctttgattggcatatacagcttgataaatctctccctgcacctctgggcact ataggtgcctggttatacagagcagaggtagctctgagggaggaaattaccattcagcag gtccatgaggaaacggccaacacaatacaacggaaacgtgagcaacacaaggatctgctt caaaacacagatgcccacaaaagagcattccatgagatctaccggaccaggtctgttaac gggatcccagtgccacctgaccaattagaggacatggcagaaaggtttcattttgtttcc tccacatcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctc tcactgctggttcttgcagagtcaaagctgaaatcttggatcatcaagtatgggaggaga gagtcagtggagctgcttctgcaaaactatatctcttttatagaaaataccaagttcttt gaacagtatgaagtgacataccagatcttaaaacagacagcggagatgtacatccaagct gatggttcagtggaagaagctgagaatgtgatgaaattcatgaatgaaaccactgcccag tggaggaacctctcagtggaagttaggagtgtgcggagcatgcttgaagaagtcatcgct aactgggatcgatatggcaatacggtggccagtcttcaggcctggctggaggatgctgag aaaatgctaaatcagacagagcacgctaaaaaggattttttccgaaatttgcctcactgg atacagcagcatgctgccatgaatgatgcaggcaattttctaattgaaacatgtgatgag atggtttcccgagaccttaaacagcagttgctattgctcaatgggcgatggagggagttg ttcatggaagtcaagcaatatgctcgggctgatgagctggacagaatgaagaaggaatac acagactgtgtcactgccctgtctgattttgcaatgggagcccataagaaactttccgaa cccttagaagtctcttttcttaatgtcaagctattaattcaagacttggaggacattgag cagagggtgcctgtaatggatgctcaatacaagatgattacaaagactgcacacctcatt accaaagagagttcccaagaagaagctaatgaaatgtttgcaaccatgtctgggctcaaa gaacagctaaccaaggtcaaggactgttactctccactcctttatgagtctcagcagctg ttgataccattggaagaattagaaaagcagatgacattcttttatgactcagttgggaaa atcaatgaaattttaacagttcttgagcatgaggcacaatctagtgctgtttttaaacag aaacaacaggaactgtcagcttgtcaagaaagctgtaagaaaaccatgacacaaattgag aaaggcagtcaaaatgttcaaaagttcatgaccttgagcagtgtgttaaagcattttgat cagacaaagctgcacagacagattgcagatgcccatggtgctttccagaatatgatgaag aaaattggagactggaagaaacatgtggaaaccaatagtcgtttgatgaagaaatttgag gagtctcgagcagagttggagaaggtgctgcggatagctcaggagggcttggaagaaaag ggaaatccagaagacctcctgaggagacataccgagttcttcagccagctggaccagaga gtgctcaatgctttcctaaaagcttgtgatgagctcaccgacattctccctgagcaggaa cagcagggcctacaggaagctgttagaaagctccacaaacagtggaaggatcttcaagga gaagccccatatcatttgcttcatctgaagattgatgtggagaagaatagattcttagct tctgtagaagaatgcaggactgagctggatcgagagaccaagctggtgccccaggaaggc agtgaaaagattattaaagagcacaggattttcttcagtgacaaaggtcctcatcatgtt tgtgagaaaaggttacagcttattgaagaactgtgtctgaagctcccaggccgggaccca gtaaggaacacacctgaaacctgtcacgtgactctcaaagagctcagagctgccattgat accacctatatgaagctcgtggaggacccagacaagtggaaggactatactagcagaatt tctcagttctcatcttggatatctgcaaaggagacagagttgaaagggtttaagaatgag cccatcgatactgccaaccatggaaaggttaaacatgctgtagaggagatcagaaatgat gttaccacaaagggcgagactctcaactggctgaaatccaggcttaaagttttaattgaa gtttcttctgagaatgaagcccaaaagcaaggagatgagctagcaaaattatctggttct ttcaaagctcttgtagctttattgtcagaggttgaaaagatgttaagcaactttggggac tgtgtccagtacaaagaaatagttaaaagctcccttgaggagttaatttctggctctaaa gaaatccaggaacaagctgagaagatcctggacactgaaaatctgtttgaagcacagcag ttacttcttcatcaccagcaaaagacaaagaggatttctgcaaagaagagagatgtgcag cagcagatacagcaggcacagcagggagaaggtgggctgccgggccaagtccgggaggag ctgcgaaagctggagagcaccctggacaacatggagcacagcagggagaaacaggaacgc cgcatccaggtcacattaagaaagtgggagcgatttgaaacgaacaaagagacagtggtc agatacctttttcaaacaggttccagccatgagcgcttcctaagttatagcagtttggaa agtttatcttcagaattggaacagacaaaggagttttctaaacgaacagaaggtattgca gtccaggctgaaaatcttgtgaaggaagcttctgagataccacttgggcccaaaaataag cagctgcttcagcagcaggccaagtcaatcaaagagcaagtcaaaaaattagaagacaca cttgaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcaat aattttgagaccctgtccatctggataactgagaaagaaaaagaactcaataccttggaa acttcgtcatctgccatggacatgcaaatcaaccagattaaggtcataattcaggaaata caaagcaagctcagcagtattacagagctagaagaatcagctcaatcttttgctcagttt 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cagcatttgttatctgagatggagtcactcaagccaaaggtccatgctgtgcagatttgc cagagtgcactgaggatccctgaagatgtggtcaccagcttgccactgtgccatgctgct ctgcacctgcaggaggaggccagccggttacagcacacagcaatccagcagtgcaacatc atgcaggaggctgtggtgcaatatgaacagtatgagcaagaaatgcagcacctccgggag cttatagaaggagcgcacagagaaatcgaggatacacctgtggccaccagtaacatccag gagctgcaagcccagatttctcggcatgaggagctggctcagaaaatcaagggctaccag gagcagatcgcctctttgaactccaagtgcaagatgctgacgatgaaagccaagcacgcc accatgctgctgacggtcacggaggtggaggggctggcggaggggacggaggacctggac agggagctcctccccgcgacctcggcccacccctctgtggtcatgatgactgcaggtcgt tgtcacactttgctgtcacctgtgacggaggagtctggggaggagggaaccaacagtgaa atttcctctccacctgcctgtcgctccccttcacctgtggctaatgcagatgcctctgtt aaccaggacattgcttattaccaagcactatctgctgagaggttacagactgatgccgca aggatccaccccagcacattgccatctcaggagttctacgaaccaggactggagccatct gctactgctaaactggatgatttgcagcgttcttgggaaaccttaaagaatgtgataagt gaaaagcagcgcactctctatgaagctttggaacgccagcagaagtaccaggactcccta cagtccatctccacaaagatggaggccattgagatgaaactcagtgagagtctggagcat 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ctacagaatgttctggaacaggaacaagagcaagtgctatacagcaggccaaatcggctc ctgtctggtgtgccactatacaaaggggatgggcagacccaagacaaatctgcagtgaca tctttgctggatggattgaaccaggtcttcgaagaggtttcatcacagagtggggggaaa aagaggcagaacattcacttggaacagaagttatatgatggggtgtcagctacttccaca tggttggatgatgttgaggaacgtttatttgttgccacagcacttttaccagaagaaaca gaagcttgcctcttcaaccaagagactcttgccaaagatattaaggaaatgtctgaagaa atggataagaacaggaacttgttttcccaagcatttccagagaatggtgataaccgagat gtcattgaagacactttgggttgtcttttgggcaggttgtccttgctagactcagtagta aatcagcgctgtcatcagatgaaggaaagacttcagcaaatactaaatttccagaatgat ctgaaggtgctgtgtacatcactggctgacaacaaatacatcattctacagaaactggca aatgtgtttgaacaacctgtggcagagcaaatagaggcaatacaacaggctgaagatggg ctaaaggaactggatgcaggaatcattgaattaaaaaggcgtggtgacaagttgcagatt gagcagccttccatgcaggaactgtccaaacttcaggatatgtatgatgaactaatgatg accataggctcccggcggagtggtctgaaccagaaccttgcactcaagagtcagtacgaa agggccctgcaagatctggctgacctgctcgagactggacaggagaagatggcaggtgac cagaaaatcattgtgtcttccaaagaggaaattcaacaactacttgacaaacataaggaa tattttcagggcctggaatctcatatgatcttgactgaaacactcttcagaaagataatc agctttgcagtcccacaggaaactcagttccacacagaactgatggcacaggcttcagct gtactaaaacgggcccacaagaggggtgtggagttggagtacattctagagacatggtct catctggatgaagactatcaggagctcagcagacagctggaggtggtagaaagtagcatc ccaagtgtggggttggtggaagaaagtgaggacaggctcatcgaccggattgcactttat cagcacttgaaatccagccttaatgaataccagcccaaattatatcaggtattagatgat gggaaacgactgcttatatccattagctgctcagatctagaaggccagctaaatcaactt ggagaacactggttaaataataccaacaaagtgtctaaggaacttcacagattggaaaca gtattgaaacactggaccagatatcaaagcgaatctgtagaacttattcactggttgcaa tctgcaaaagacaggctagaattttggactcaacaatctgtgacagtcccacaagaactg gaaatggtccgtgatcatctaaatgccttcctggagttttccaaagaagtggatgccaaa tcttctctgaaatcgtctgtcctcagcactggaaatcagcttcttcgattaaagaaagta gacacagctgccctacgttcagagctgtcacacattgatagccaatggactgacctgctg acaaatattccaactgtacaggaaaagctccatcagctccaaatggataagctgccttcc cgtcatgccatttctgaagttatgacttggatttctcttatggaaaatgttattcaaaag gatgaagagaatatacaaaattcagtaggttacaaggcaattcatgaataccttcagaaa tataagggttttaagatagatattaactgtaaacagttgacagttgattttgtgaatcag tctgtgctacaaatcagtagtcaggatgtggaaagtaaacgcagtgataagactgatttt gctgaacaacttggagccatgaataaaagttggcaaatcctgcagggtctagtgactgag aagatccagctgttggaaggcttattggaatcttggtcagaatatgaaaataatgtacaa agtctgaaaacttggtatgaaacccaggaaaacagactaaagcaacagcatcgaattgga gatcaggcttcagttcagaacgcaatgaaagactgtcaggatctagaagatttggttaaa gcaaaagaaaaagaggtagagagaattgagcagagtggacttgctttgattcagaacaag aaagaagaagtctctggcattgtcatgagcacgctgcgggagctgaaccaaacctgggca aatttagaccacatggttgggcaattaaagatactgttgaagtccgtgtttgaccaatgg aacaatcacaaggtggcctttgatgagataaacagctacctcatggaggccagatattct ctttcccgcttccgtctgctgactggctctttagaagctgtacaagttcaggtagacaat cttcagaatcttcaagatgatctggaaaaacaggaaaagaacctacagaggtttggctct atcaccaaccaactgttaaaagagtgtcacccacctgtgacagaaactcttaccaataca ttaaaagatgtcaatatgagatggaataatttgctggaagagatttctgagcagctgcac tccagcaaagccctacttcaactctggcaaagatacaaggactactcccaacagtgtgct tctacagttcagcagcaagaggaccgaaccaatgagctcttgaaggcagccactaacaag gacattgctgatgacgaagctgctacatggattcaagattgcaatgatctcctcaaagga ctggggatagtgaaggattccctttttgttctccatgagctgggagagcagctcaagcaa caagtggatgcttcagcggcatcagccattcaatctgatcagctgtctttgagtcaacac ctatgtgccctagaacaggctctttgcaagcagcagactacattacaggttggagttctt gactatgagacctttaccaagagtttagaagcattggaggcctggatagtagaagctgaa gacatattacaagggcaggaccctagccactcatctgacctctcaaccattcaggaaagg atggaagaacttaagggacagatgttaaaattcagcagtatggcccctgatctagaccgt ctaaatgagcttgggtataggctaccactgaatgataaagaaatcaaaaggatgcagaat ctgaaccggcgctggtctctgatctcctctcagaccacagaaagattcagtaagttgcaa tcatttttgctacaacatcagactttcttggaaaaatgtgaaacatggatggaattcctg gttcaaacggaacaaaaattagcagtagagatttcaggcaattatcagcatcttttggag cagcagagagcgcatgagttgtttcaagcagagatgtttagtcgtcagcagattttgcac tcaatcattattgatggtcagcgtcttctagaacaaggtcaagttgatgacagggatgaa ttcaacctgaaattgacacttctcagcaatcagtggcagggagtgattcgccgggcccag cagaggaggggcatcattgacagccagattcgccagtggcagcggtacagggagatggca gagaagcttcgtaaatggttggttgaagtgtcctatcttcccgtgagtgctctcggaagt gtcccaataccactgcaacaggcaaggaccctctttgatgaagtgcagttcaaagaaaaa gtgttcctgcgacagcaaggcagttacatcctaacagtggaggctggcaagcagctcctg ctctcagcggacagtggggctgaggctgccttgcaagcagaactcactgaaatccaagag aagtggaaatcagccagcgtgcgtttggaggaacagaagaaaaaactggccttcttgttg aaagactgggaaaactgtgagaacggaatagctgattctctggagaaactacgaactttc aaaaagaagctttctcagcctcttccagatcaccatgaggagctgcatgcagagcaaatg cgttgcaaggagctggaaaatgtagctgggagctggacagatgatatggctcagctgaca ctgctgaaggatactctctgtgcctacatcagcgccgatgatatctccatcctgaatgaa cgcatggagcttctgcaaaggcagtgggaagaactgtgccaccagctctccttaaggcgg cagcaagtaagtgaaagattgaatgaatgggcagtcttcagtgaaaagaacaaggagctt tgtgaatggttgacccagatggaaagcaaagtttctcaaaatggagacatcctcattgaa gatatgatagaaaagctcaagaaggattatcaagaggaaattgctgttgcccaagagaac aaaatacagctccagcaaatgggagaacgacttgctagagccagccatgaaagcaaagcc tctgagattgaatacaaactcggaaaggttaatgacaggtggcagcatctcctggatctc atggcagccagggtaaagaagctgaaggagaccctggttgccgtacagcagctggataag aacatgagcagcctgaggacgtggctggctcacatcgagtcagagctggccaagcccata gtctatgattcctgtgactcggatgaaatacagaaaaagcttactgagcagcaggagctt cagagagacattgagaaacatagcacaggcgtggcctctgttctcaacttatgtgaggtc ctgcttcatgactgtgatgcctgcgccacggatgcagagtgtgattccatccagcaggcg acgcgaaacctggaccggcgatggagaaatatctgtgccatgtccatggaaagaaggctc aaaattgaagagacatggcgattgtggcagaagtttctcgatgattattctcgttttgaa gattggctcaagatttcagaaaggacagctgccttccccagctcttctggggtgctctat acagttgccaaggaagaactaaagaaatttgaggctttccagcgacaggtccacgagagc ctgacccagctagaactaatcaacaagcagtaccgtcgcctggccagagagaaccgcacc gattctgcttgtagcctaaagcagatggttcatgaaggcaaccagagacgggacaacctg caaaagcgtgtcacctccatcttgcgcagactcaagcatttcattggccagcgtgaggaa tttgagactgcacgggacagcattctggtgtggctgacagagatggatctacagctcact aatattgagcatttttctgagtgtgatgttcaagctaaaataaagcaactcaaggccttc cagcaagaaatttcactgaaccacaataagattgagcacataattgcccaaggagaacag cttatagaaaagagtgagcccttggatgcggcagtcattgaggaagagctagatgaactc cggcgttactgtcaggaagtctttgggcgtgtggaaagataccataagaaactgattcgc ctgcctctcccagatgatgagcatgacctctctgaccgggagctggagctggatgactct 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cgctgggaccatgtgtgctcattgctagaagagtggcggggcctgctccaagatgcactg atgcagtgtcaggatttccatgaaatgagtcatggtttgctgcttatgctggagaacatc gacagaaggaaaaatgaaattgtccctattgattctaaccaggatgcagagacacttcag gaccatcacaaacagcttatgcaaataaggcatgagctgttggaatcccagctcaaagtg gcctcactgcaagacatgtcttgccaactcttggtgaatgctgaaggcacagattgttta gaagccaaagaaaaagtccatgtgattggaaatcggctcaaacttctcttgaaggaggtc agtcgtcacatcaaggagctggagaagttattagatatgtcaagcagtcagcaggatttg tcttcctggtcttctgctgatgaactggacacctcaggatctgtgagtcctacatcagga agaagcaccccaaacagacaaagaacgccacgaggcaaatgtagtctctcacagcctgga ccctctgtcaacagtccacatagcaggtccataaaaggtggctccgattcctccctttct gagcctcagccagctcggtccggccgagccttcctattcagagtcctccgagcggctctt ccacttcagcttctcctgcttctcctcatcgggctcgcctgccttgtaccaatgtcagag gaagactatagttgtgccctctccaacaactttgcccgatcattccaccccatgctcaga tacacaaatggccctcctccgctctga

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