KEGG   Zalophus californianus (California sea lion): 113914948
Entry
113914948         CDS       T07874                                 
Symbol
RELA
Name
(RefSeq) transcription factor p65
  KO
K04735  transcription factor p65
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01523  Antifolate resistance
zca04010  MAPK signaling pathway
zca04014  Ras signaling pathway
zca04024  cAMP signaling pathway
zca04062  Chemokine signaling pathway
zca04064  NF-kappa B signaling pathway
zca04066  HIF-1 signaling pathway
zca04071  Sphingolipid signaling pathway
zca04137  Mitophagy - animal
zca04151  PI3K-Akt signaling pathway
zca04210  Apoptosis
zca04211  Longevity regulating pathway
zca04218  Cellular senescence
zca04380  Osteoclast differentiation
zca04613  Neutrophil extracellular trap formation
zca04620  Toll-like receptor signaling pathway
zca04621  NOD-like receptor signaling pathway
zca04622  RIG-I-like receptor signaling pathway
zca04623  Cytosolic DNA-sensing pathway
zca04625  C-type lectin receptor signaling pathway
zca04657  IL-17 signaling pathway
zca04658  Th1 and Th2 cell differentiation
zca04659  Th17 cell differentiation
zca04660  T cell receptor signaling pathway
zca04662  B cell receptor signaling pathway
zca04668  TNF signaling pathway
zca04722  Neurotrophin signaling pathway
zca04917  Prolactin signaling pathway
zca04920  Adipocytokine signaling pathway
zca04926  Relaxin signaling pathway
zca04931  Insulin resistance
zca04932  Non-alcoholic fatty liver disease
zca04933  AGE-RAGE signaling pathway in diabetic complications
zca04936  Alcoholic liver disease
zca05010  Alzheimer disease
zca05022  Pathways of neurodegeneration - multiple diseases
zca05030  Cocaine addiction
zca05132  Salmonella infection
zca05133  Pertussis
zca05134  Legionellosis
zca05135  Yersinia infection
zca05140  Leishmaniasis
zca05142  Chagas disease
zca05145  Toxoplasmosis
zca05146  Amoebiasis
zca05152  Tuberculosis
zca05160  Hepatitis C
zca05161  Hepatitis B
zca05162  Measles
zca05163  Human cytomegalovirus infection
zca05164  Influenza A
zca05165  Human papillomavirus infection
zca05166  Human T-cell leukemia virus 1 infection
zca05167  Kaposi sarcoma-associated herpesvirus infection
zca05168  Herpes simplex virus 1 infection
zca05169  Epstein-Barr virus infection
zca05170  Human immunodeficiency virus 1 infection
zca05171  Coronavirus disease - COVID-19
zca05200  Pathways in cancer
zca05202  Transcriptional misregulation in cancer
zca05203  Viral carcinogenesis
zca05207  Chemical carcinogenesis - receptor activation
zca05208  Chemical carcinogenesis - reactive oxygen species
zca05212  Pancreatic cancer
zca05215  Prostate cancer
zca05220  Chronic myeloid leukemia
zca05221  Acute myeloid leukemia
zca05222  Small cell lung cancer
zca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
zca05321  Inflammatory bowel disease
zca05415  Diabetic cardiomyopathy
zca05417  Lipid and atherosclerosis
zca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113914948 (RELA)
   04014 Ras signaling pathway
    113914948 (RELA)
   04064 NF-kappa B signaling pathway
    113914948 (RELA)
   04668 TNF signaling pathway
    113914948 (RELA)
   04066 HIF-1 signaling pathway
    113914948 (RELA)
   04071 Sphingolipid signaling pathway
    113914948 (RELA)
   04024 cAMP signaling pathway
    113914948 (RELA)
   04151 PI3K-Akt signaling pathway
    113914948 (RELA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    113914948 (RELA)
  09143 Cell growth and death
   04210 Apoptosis
    113914948 (RELA)
   04218 Cellular senescence
    113914948 (RELA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    113914948 (RELA)
   04620 Toll-like receptor signaling pathway
    113914948 (RELA)
   04621 NOD-like receptor signaling pathway
    113914948 (RELA)
   04622 RIG-I-like receptor signaling pathway
    113914948 (RELA)
   04623 Cytosolic DNA-sensing pathway
    113914948 (RELA)
   04625 C-type lectin receptor signaling pathway
    113914948 (RELA)
   04660 T cell receptor signaling pathway
    113914948 (RELA)
   04658 Th1 and Th2 cell differentiation
    113914948 (RELA)
   04659 Th17 cell differentiation
    113914948 (RELA)
   04657 IL-17 signaling pathway
    113914948 (RELA)
   04662 B cell receptor signaling pathway
    113914948 (RELA)
   04062 Chemokine signaling pathway
    113914948 (RELA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    113914948 (RELA)
   04917 Prolactin signaling pathway
    113914948 (RELA)
   04926 Relaxin signaling pathway
    113914948 (RELA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    113914948 (RELA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    113914948 (RELA)
  09149 Aging
   04211 Longevity regulating pathway
    113914948 (RELA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113914948 (RELA)
   05202 Transcriptional misregulation in cancer
    113914948 (RELA)
   05207 Chemical carcinogenesis - receptor activation
    113914948 (RELA)
   05208 Chemical carcinogenesis - reactive oxygen species
    113914948 (RELA)
   05203 Viral carcinogenesis
    113914948 (RELA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113914948 (RELA)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    113914948 (RELA)
   05221 Acute myeloid leukemia
    113914948 (RELA)
   05220 Chronic myeloid leukemia
    113914948 (RELA)
   05215 Prostate cancer
    113914948 (RELA)
   05222 Small cell lung cancer
    113914948 (RELA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113914948 (RELA)
   05170 Human immunodeficiency virus 1 infection
    113914948 (RELA)
   05161 Hepatitis B
    113914948 (RELA)
   05160 Hepatitis C
    113914948 (RELA)
   05171 Coronavirus disease - COVID-19
    113914948 (RELA)
   05164 Influenza A
    113914948 (RELA)
   05162 Measles
    113914948 (RELA)
   05168 Herpes simplex virus 1 infection
    113914948 (RELA)
   05163 Human cytomegalovirus infection
    113914948 (RELA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113914948 (RELA)
   05169 Epstein-Barr virus infection
    113914948 (RELA)
   05165 Human papillomavirus infection
    113914948 (RELA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113914948 (RELA)
   05135 Yersinia infection
    113914948 (RELA)
   05133 Pertussis
    113914948 (RELA)
   05134 Legionellosis
    113914948 (RELA)
   05152 Tuberculosis
    113914948 (RELA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    113914948 (RELA)
   05145 Toxoplasmosis
    113914948 (RELA)
   05140 Leishmaniasis
    113914948 (RELA)
   05142 Chagas disease
    113914948 (RELA)
  09163 Immune disease
   05321 Inflammatory bowel disease
    113914948 (RELA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113914948 (RELA)
   05022 Pathways of neurodegeneration - multiple diseases
    113914948 (RELA)
  09165 Substance dependence
   05030 Cocaine addiction
    113914948 (RELA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113914948 (RELA)
   05418 Fluid shear stress and atherosclerosis
    113914948 (RELA)
   05415 Diabetic cardiomyopathy
    113914948 (RELA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    113914948 (RELA)
   04932 Non-alcoholic fatty liver disease
    113914948 (RELA)
   04931 Insulin resistance
    113914948 (RELA)
   04933 AGE-RAGE signaling pathway in diabetic complications
    113914948 (RELA)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    113914948 (RELA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:zca03000]
    113914948 (RELA)
Transcription factors [BR:zca03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    113914948 (RELA)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer
Other DBs
NCBI-GeneID: 113914948
NCBI-ProteinID: XP_027436376
EnsemblRapid: ENSZCAG00025011130
UniProt: A0A6J2BZ88
LinkDB
Position
11:complement(106760566..106768913)
AA seq 539 aa
MDDLFPLIFPSEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPAGRPLRLSPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFNGPTDPRPPPRRIAVPSRSTTSVPKPAPQSYPFTPSLSTINF
EEFSPMVFSSGQIPNQTSALAPAPAPILAPAPAPAPAPILAPGLAQAVVPPAPKTTQAGE
GTLSEALLQLQFDADEDLGALLGNSADPAVFTDLASVDNSEFQQLLNQGVSVAPHTAEPM
LMEYPEAITRLVTGSQRPPDPTPAPLGASGLPNGLLSGDEDFSSIADMDFSALLSQISS
NT seq 1620 nt   +upstreamnt  +downstreamnt
atggacgacctgtttcccctcatcttcccgtctgagcctgcccaggcctccggcccctat
gtggagatcatcgagcagcccaagcagcggggcatgcgcttccgctacaagtgcgagggg
cgctccgccggcagtatcccgggcgagaggagcactgataccaccaagacccaccccacc
atcaagatcaatggctacactgggccagggacagttcgcatctccctggtcaccaaggac
ccccctcaccggcctcacccccatgagcttgtggggaaagactgccgggatggcttctat
gaggctgagctctgcccagaccgctgcatccacagcttccagaacctggggatccagtgt
gtaaagaagcgggacctggagcaggccatcagtcaacgcatccagaccaacaacaatccc
ttccaagttcccatagaagaacagcgtggggactacgacctgaatgcggtgcgactctgc
ttccaggtgacagtgcgggacccggcaggcaggcccctccgcttgtcacctgtcctctct
catcccatctttgacaaccgtgcccccaataccgccgagctcaagatctgccgagtgaac
cgaaactctgggagctgcctcgggggggatgagatcttcctgctgtgtgacaaggtgcag
aaagaggacattgaagtatatttcaccggaccaggctgggaggcccgaggctccttttct
caagctgacgtccaccgacaagtggccattgtgttccggacacctccctacgctgacccc
agcctgcaggcccccgtgcgtgtctccatgcagctgcggcggccttcagatcgggagctc
agcgagcccatggaattccagtacttgccagacacagatgatcgtcaccggattgaggag
aaacgcaaaaggacatatgagaccttcaagagcatcatgaaaaagagtcctttcaatgga
cccaccgacccccggcctccaccccggcgcattgctgtgccttcccgaagcacaacttcc
gttcccaagccagctccccagtcctatccctttacgccgtccctcagcaccatcaacttc
gaggagttctcccccatggtcttttcttcggggcagatcccaaaccagacctctgccttg
gccccggcccctgccccaatcctggccccagcccctgccccagcccctgccccaatctta
gccccaggccttgctcaggctgtggtccccccagcccccaagaccacccaggccggggaa
gggacgctgtcagaggccctgctgcagctgcagtttgatgccgacgaagacctgggggcc
ctgctgggcaacagcgctgaccctgccgtgttcacagacctggcatccgttgacaactct
gagtttcagcagctcctgaaccagggtgtatctgtggccccacacacagccgagcccatg
ctcatggagtaccctgaggcaataacgcgcctggtgacagggtcccagaggccccctgat
ccaactcctgctcccctaggggcctctgggctccccaacggcctcctctcaggggatgaa
gacttctcctccatcgcagatatggacttctcagcccttctgagtcagatcagctcctaa

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