S-adenosyl-L-methionine [CPD:C00019];
adenine1618 in 23S rRNA
Product
S-adenosyl-L-homocysteine [CPD:C00021];
N6-methyladenine1618 in 23S rRNA
Comment
The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA [1].
History
EC 2.1.1.181 created 1976 as EC 2.1.1.48, part transferred 2010 to EC 2.1.1.181
Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA
Title
The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.