KEGG ENZYME: 2.7.1.206

ENZYME: 2.7.1.206

Entry

EC 2.7.1.206                Enzyme

Name

protein-Npi-phosphohistidine---L-sorbose phosphotransferase;
sorABFM (gene names);
L-sorbose PTS permease;
EIISor;
Enzyme IISor

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

protein-Npi-phospho-L-histidine:L-sorbose Npi-phosphotransferase

Reaction(IUBMB)

[protein]-Npi-phospho-L-histidine + L-sorbose[side 1] = [protein]-L-histidine + L-sorbose 1-phosphate[side 2] [RN:R04076]

Reaction(KEGG)

R04076

Substrate

[protein]-Npi-phospho-L-histidine [CPD:C04261];
L-sorbose[side 1] [CPD:C00247]

Product

[protein]-L-histidine [CPD:C00615];
L-sorbose 1-phosphate[side 2] [CPD:C02888]

Comment

This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate---protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.

History

EC 2.7.1.206 created 1972 as EC 2.7.1.69, part transferred 2016 to EC 2.7.1.206

Pathway

ec00051

Fructose and mannose metabolism

ec01100

Metabolic pathways

Orthology

K02812

sorbose PTS system EIIA component

K02813

sorbose PTS system EIIB component

Genes

ECE:	Z5616 Z5617

ECS:	ECs_5001(sorB) ECs_5002(sorF)

ECF:	ECH74115_5497

ETW:	ECSP_5094 ECSP_5095

ELX:	CDCO157_4684 CDCO157_4685

EOI:	ECO111_4837 ECO111_4838

EOJ:	ECO26_5130 ECO26_5131

ECOO:

ECRM13514_5147 ECRM13514_5148

ECOH:

ECRM13516_4884 ECRM13516_4885

ECG:	E2348C_4333 E2348C_4334

EOK:	G2583_4843(sorB) G2583_4844(sorF)

ELR:	ECO55CA74_23170 ECO55CA74_23175

EUN:	UMNK88_4870 UMNK88_4871

ECP:	ECP_4236 ECP_4237

ENA:	ECNA114_4174 ECNA114_4175

ECOS:

EC958_4473 EC958_4474

ECV:	APECO1_2449 APECO1_2450

ECOA:

APECO78_00875 APECO78_00880

ECM:	EcSMS35_4479 EcSMS35_4480

ECQ:	ECED1_4733 ECED1_4734

EUM:	ECUMN_4551 ECUMN_4552

ECT:	ECIAI39_4415 ECIAI39_4416

EOC:	CE10_4707(sorB) CE10_4708

ECI:	UTI89_C4586 UTI89_C4587

EIH:	ECOK1_4503 ECOK1_4504

ECZ:	ECS88_4491 ECS88_4492

ECC:	c4984 c4985

ELO:	EC042_4387(sorB) EC042_4388(sorF)

ELN:	NRG857_20075 NRG857_20080

ESE:	ECSF_3875 ECSF_3876

EAB:	ECABU_c45410 ECABU_c45420

ELU:	UM146_20205 UM146_20210

ELC:	i14_4573 i14_4574

ELD:	i02_4573 i02_4574

ELF:	LF82_635 LF82_636

ECOI:

ECOPMV1_04398(sorB) ECOPMV1_04399(manX_7)

ECOJ:

P423_22300 P423_22305

EFE:	EFER_4080 EFER_4081

EAL:	EAKF1_ch1894 EAKF1_ch1895(manX)

EMA:	C1192_18410 C1192_18415

ESZ:	FEM44_11860 FEM44_11865

SFL:	SF4091(sorB) SF4092(sorF)

SFX:	S3638(sorF) S3639(sorB)

SFV:	SFV_4096(sorB) SFV_4097(sorF)

SFE:	SFxv_4461 SFxv_4462

SFN:	SFy_5869 SFy_5870

SFS:	SFyv_5936 SFyv_5937

SFT:	NCTC1_04447(sorB) NCTC1_04448(manX_4)

SSN:	SSON_4197(sorF)

SBO:	SBO_4046(sorB) SBO_4047(sorF)

SBC:	SbBS512_E4522

ENF:	AKI40_0087 AKI40_0088

KPN:	KPN_04405(manX) KPN_04406(manX)

KPM:	KPHS_02390 KPHS_02400

KPH:	KPNIH24_01310 KPNIH24_01315

KPW:	KPNIH30_01340 KPNIH30_01345

KPY:	KPNIH31_01340 KPNIH31_01345

KPG:	KPNIH32_01345 KPNIH32_01350

KPC:	KPNIH10_01305 KPNIH10_01310

KPQ:	KPR0928_01310 KPR0928_01315

KPT:	VK055_3068 VK055_3069(manX2)

KPO:	KPN2242_00065 KPN2242_00070

KPR:	KPR_0387(sorA)

KPJ:	N559_4895 N559_4896

KPI:	D364_22435 D364_22440

KPA:	KPNJ1_05187 KPNJ1_05188

KPS:	KPNJ2_05185 KPNJ2_05186

KPNE:

KU54_025385 KU54_025390

KPNU:

LI86_25225 LI86_25230

KPNK:

BN49_5027(sorF) BN49_5028(sorB)

KVA:	Kvar_4840 Kvar_4841

KPE:	KPK_5268(sorF) KPK_5269(sorB)

KPK:	A593_12115 A593_12120

KVD:	KR75_09555 KR75_09560

KVQ:	SP68_16145 SP68_16150

KOX:	KOX_08110 KOX_08115

KOE:	A225_0286 A225_0287

KOY:	J415_01630 J415_01635

KOM:	HR38_06785 HR38_06790

KOK:	KONIH1_01650 KONIH1_01655

KOC:	AB185_05475 AB185_05480

KQV:	B8P98_26195 B8P98_26200

KLL:	BJF97_01500 BJF97_01505

KLW:	DA718_27650 DA718_27655

KAR:	LGL98_23640 LGL98_23645

KGR:	JJJ10_26115 JJJ10_26120

KPAS:

LUW96_08260 LUW96_08265

KLC:	K7H21_26245 K7H21_26250

KLM:	BWI76_01735 BWI76_01740

REE:	electrica_04781(manX_4) electrica_04782(sorB)

ROR:	RORB6_17415 RORB6_17420

RON:	TE10_03640 TE10_03645

RPLN:

B1209_25500

RAO:	DSD31_24325 DSD31_24330

RTG:	NCTC13098_06890(manX_11) NCTC13098_06892(sorB_2)

CBRA:

A6J81_15555 A6J81_15560

CYO:	CD187_22505 CD187_22510

CPOT:

FOB25_09780 FOB25_09785

CAMA:

F384_22140 F384_22145

CAF:	AL524_04920 AL524_04925

CIF:	AL515_02795 AL515_02800

CFAR:

CI104_23545 CI104_23550

CIR:	C2U53_11505 C2U53_11510

CPAR:

CUC49_20795 CUC49_20800

CTEL:

GBC03_06365 GBC03_06370

CITZ:

E4Z61_15570 E4Z61_15575

CIX:	M4I31_22180 M4I31_22185

CEN:	LH86_06510 LH86_06515

KOO:	O9K67_00435 O9K67_00440

KIN:	AB182_23575 AB182_23580

PSGC:

G163CM_32910(sorF) G163CM_32920(sorB)

EBF:	D782_4247 D782_4248

YEN:	YE0813(sorB) YE0814(sorF)

YEP:	YE105_C0701 YE105_C0702

YEY:	Y11_22381 Y11_22391

YEL:	LC20_04325 LC20_04326

YEW:	CH47_2673 CH47_2674(sorB)

YET:	CH48_2517(sorB) CH48_2518

YEF:	FORC2_3284 FORC2_3285

YEE:	YE5303_25211(sorF) YE5303_25221(sorB)

YFR:	AW19_13(sorB) AW19_14

YIN:	CH53_867 CH53_868(sorB)

YKR:	CH54_1648 CH54_1649

YMA:	DA391_17835 DA391_17840

YHI:	D5F51_14890 D5F51_14895

YCA:	F0T03_04675 F0T03_04680

YMO:	HRD69_09890 HRD69_09895

YAS:	N0H69_04405 N0H69_04410

YKI:	HRD70_08985 HRD70_08990

GQU:	AWC35_15440 AWC35_15445

GAP:	GAPWK_0307 GAPWK_0308

PACE:

A6070_08410

DES:	DSOUD_1307

DVM:

DvMF_0422

OJD:	NP439_24010

BMUR:

ABE28_013770

ACUR:

JZ785_23080

STK:

STP_1527

SPAT:

A0O21_09945 A0O21_09950

SCHJ:

DDV21_000310 DDV21_000315

LAW:	LACWKB8_0333 LACWKB8_0334

LHS:	DLD54_01590 DLD54_01595

LCS:	LCBD_0428 LCBD_0429

LCE:	LC2W_0423 LC2W_0424

LCW:	BN194_04330(levD) BN194_04340(sorB)

LCB:	LCABL_04250(sorA) LCABL_04260(sorB)

LRL:	LC705_00408(sorA) LC705_00409(sorB)

LRA:	LRHK_421 LRHK_422(sorB)

LRO:	LOCK900_0394 LOCK900_0395

LRC:	LOCK908_0415 LOCK908_0416

LNG:	BSQ50_04820 BSQ50_04825

LMAL:

LM596_09975 LM596_09980

BFP:	MOO45_04310 MOO45_04315

EGV:	EGCR1_11510 EGCR1_11515

EAV:	EH197_22890 EH197_22895

ERAF:

J9537_13590 J9537_13595

EMS:	P3T75_00105

TKR:	C7K43_01675

ACG:	AWM71_03595

CBK:

CLL_A3359

CBEI:

LF65_05130

CPAS:

Clopa_1339 Clopa_1340

CPAT:

CLPA_c28990(sorB) CLPA_c29000

CPAE:

CPAST_c28990(sorB) CPAST_c29000

CDY:	F3K33_23370

BPRL:

CL2_07370 CL2_07380

TTO:	Thethe_01741

APR:

Apre_0157

ERL:	AOC36_10705

FCZ:	IMF26_04720

PSUB:

Pelsub_P0901

STR:	Sterm_1992 Sterm_1993

» show all

Reference

1 [PMID:7700234]

Authors

Wehmeier UF, Wohrl BM, Lengeler JW

Title

Molecular analysis of the phosphoenolpyruvate-dependent L-sorbose: phosphotransferase system from Klebsiella pneumoniae and of its multidomain structure.

Journal

Mol Gen Genet 246:610-8 (1995)
DOI:10.1007/bf00298968

Sequence

[kvq:SP68_16150 SP68_16145]

Reference

2 [PMID:10613875]

Authors

Yebra MJ, Veyrat A, Santos MA, Perez-Martinez G

Title

Genetics of L-sorbose transport and metabolism in Lactobacillus casei.

Journal

J Bacteriol 182:155-63 (2000)
DOI:10.1128/JB.182.1.155-163.2000