KEGG ENZYME: 4.1.1.38

ENZYME: 4.1.1.38

Entry

EC 4.1.1.38                 Enzyme

Name

phosphoenolpyruvate carboxykinase (diphosphate);
phosphopyruvate carboxylase (ambiguous);
PEP carboxyphosphotransferase (ambiguous);
PEP carboxykinase (ambiguous);
phosphopyruvate carboxykinase (pyrophosphate);
PEP carboxylase (ambiguous);
phosphopyruvate carboxykinase (ambiguous);
phosphoenolpyruvic carboxykinase (ambiguous);
phosphoenolpyruvic carboxylase (ambiguous);
phosphoenolpyruvate carboxytransphosphorylase (ambiguous);
phosphoenolpyruvate carboxykinase (ambiguous);
phosphoenolpyruvic carboxykinase;
phosphoenolpyruvic carboxylase;
PEPCTrP;
phosphoenolpyruvic carboxykinase (pyrophosphate);
phosphoenolpyruvic carboxylase (pyrophosphate);
phosphoenolpyruvate carboxylase (ambiguous);
phosphoenolpyruvate carboxyphosphotransferase (ambiguous);
phosphoenolpyruvic carboxytransphosphorylase (ambiguous);
phosphoenolpyruvate carboxylase (pyrophosphate);
phosphopyruvate carboxylase (pyrophosphate);
diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)

Class

Lyases;
Carbon-carbon lyases;
Carboxy-lyases

Sysname

diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)

Reaction(IUBMB)

diphosphate + oxaloacetate = phosphate + phosphoenolpyruvate + CO2 [RN:R00346]

Reaction(KEGG)

R00346

Substrate

diphosphate [CPD:C00013];
oxaloacetate [CPD:C00036]

Product

phosphate [CPD:C00009];
phosphoenolpyruvate [CPD:C00074];
CO2 [CPD:C00011]

Comment

Also catalyses the reaction: phosphoenolpyruvate + phosphate = pyruvate + diphosphate.

History

EC 4.1.1.38 created 1965

Pathway

ec00620

Pyruvate metabolism

ec01100

Metabolic pathways

Orthology

K20370

phosphoenolpyruvate carboxykinase (diphosphate)

Genes

EHI:	EHI_030750(195.t00013) EHI_166920(44.t00030) EHI_198620(34.t00028)

EDI:	EDI_082590 EDI_173460 EDI_278510

EIV:	EIN_065890 EIN_129860

TPS:	THAPSDRAFT_899

NGR:	NAEGRDRAFT_77359

GLA:	GL50803_00101278

SSAO:

94302370(SS50377_28347) 94302373(SS50377_28350)

GTT:	GUITHDRAFT_84236

MMT:	Metme_3540

MDN:	JT25_014525

MDH:	AYM39_18075

MKO:	MKLM6_3661

METL:

U737_04100

MPAD:

KEF85_11220

MELL:

IVG45_13405

MRP:	NM686_017630

MMOT:

QZJ86_17305

MEEP:

JWZ98_03720

MEEC:

PL263_11200

MEUP:

QC632_02865

MAH:	MEALZ_2193

MBUR:

EQU24_11045

MOZ:	MoryE10_04160

MISZ:

MishRS11D_33300

MESL:

KKZ03_02810

THIS:

HZT40_18115

TUN:	J9260_09965

TLO:	J9253_16855

TSB:	HMY34_08170

TANI:

J8380_16690

TPUT:

QJT81_21145

THIM:

KFB96_11170

TBOG:

LT988_06380

TNI:	TVNIR_1350

TTI:	THITH_07575

TBN:

TBH_C0778

EPS:	L0Y14_11480

SDR:	SCD_n01561

SLAC:

SKTS_27240

MEDK:

QEV83_13585

MAES:

Ga0123461_1491

MFN:	Ga0123462_0916

OTE:

Oter_4094

OBG:	Verru16b_01053

VBH:	CMV30_08260

OBT:	OPIT5_20420

CAA:

Caka_2960

RUFI:

K0V07_13780

PUO:	RZN69_09330

PPHT:

GA004_05535

VBA:	IMCC26134_08370

VBS:	EGM51_12915

RBA:

RB6610

PIR:	VN12_07235

RUL:

UC8_55490

RML:	FF011L_44340

MFF:	MFFC18_05900

ROL:	CA51_45950

AHEL:

Q31a_10380

LCRE:

Pla8534_59630

BVO:	Pan97_07860

BREM:

PSR63_06915

RLC:	K227x_62910

PBS:	Plabr_1028

PLS:	VT03_23760

FMR:	Fuma_01957

GMR:	GmarT_31400

GIM:	F1728_30220

GPN:	Pan110_30440

GFM:	Enr17x_32030

GAZ:	Pan241w_31160

GAW:	V144x_28340

GAX:	Pan161_32530

MRI:	Mal4_57980

SDYN:

Mal52_58640

AGV:	OJF2_66600

HBS:	IPV69_04310

LPRO:

PQO03_12370

SFC:	Spiaf_0914

SPER:

EW093_15265

PFER:

IRI77_32235

DORI:

FH5T_18800

DRC:	G0Q07_10925

MCOS:

GM418_24260

ASX:	CDL62_13165

MBAS:

ALGA_3186

FGL:	EM308_16940

PRN:	BW723_03070

PBAT:

JL193_08460

PUN:	NQP51_13185

POLQ:

JOP69_13340

AHZ:	APS56_12520

FOP:	FNB79_10230

SEON:

BWZ22_04855

FEK:	C1H87_15035

FAY:	Q4Q34_05085

TAY:	JJL45_04400

TAJ:	C1A40_08075

MARF:

CJ739_1125

FBE:	FF125_13765

ALUT:

O5O44_03200

AEST:

RBH94_04110

TSX:	RHP49_05145

PEI:	H9L10_07420

PAC:

PPA2334

PAK:	HMPREF0675_5414

PAV:	TIA2EST22_11560

PAX:	TIA2EST36_11420

PAZ:	TIA2EST2_11365

PAW:	PAZ_c24360

PAD:	TIIST44_04515

PCN:	TIB1ST10_11885

PACC:

PAC1_11925

PACH:

PAGK_2242

PACN:

TIA1EST1_11510

CACN:

RN83_00315

PRA:	PALO_10610

PRL:	BCB70_06670

CGRN:

4412665_01276

CEQU:

O6R08_11125

PFR:	PFREUD_02290

PFRE:

RM25_0213

PACD:

EGX94_05540

PAUS:

NCTC13651_02638

PPC:	HMPREF9154_1333

ARUB:

J5A65_08740

PBO:	PACID_16740

AACI:

ASQ49_13165

ACIJ:

JS278_01733

AJI:	C0Z10_06020

TFL:	RPIT_08485

TFA:	BW733_14605

TEZ:	BKM78_03080

TLA:	TLA_TLA_00627

TEJ:	KDB89_05130

TLS:	QH948_08985

RAIN:

Rai3103_02390

PRV:	G7070_05815

BRT:	J4N02_15205

PROP:

QQ658_12290

BROO:

brsh051_10690

MGG:	MPLG2_3394

ACQ:	AM609_14470

AOS:	AXE84_04900

ARD:	AXF14_04825

ACTC:

CHIBA101_2383

ACTO:

C3V41_09665

ANE:	ATCC27039_23250

AHW:	NCTC11636_01746

AIR:	AIF0345_3258

ASLA:

NCTC11923_00646

AVC:	NCTC10951_02266

AGH:	M3I41_08990

AMAS:

QU670_00265

ACAP:

MANAM107_10330

AUO:	R3I39_02545

ACTH:

JJJ15_07240

ACHN:

JJJ14_00130

CCOT:

CCAX7_20210

» show all

Reference

1 [PMID:4288896]

Authors

Lochmuller H, Wood HG, Davis JJ.

Title

Phosphoenolpyruvate carboxytransphosphorylase. II. Crystallization and properties.

Journal

J Biol Chem 241:5678-91 (1966)

Other DBs

ExplorEnz - The Enzyme Database:

4.1.1.38

IUBMB Enzyme Nomenclature:

4.1.1.38

ExPASy - ENZYME nomenclature database:

4.1.1.38

BRENDA, the Enzyme Database:

4.1.1.38

CAS:

9013-12-1

LinkDB

DBGET integrated database retrieval system