KEGG   COMPOUND: C07263
Entry
C07263                      Compound                               
Name
Nevirapine
Formula
C15H14N4O
Exact mass
266.1168
Mol weight
266.30
Structure
Remark
Same as: D00435
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AG Non-nucleoside reverse transcriptase inhibitors
     J05AG01 Nevirapine
      D00435  Nevirapine (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI)
   Nevirapine
    D00435  Nevirapine (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D00435  Nevirapine (JAN/USP/INN)
Drug groups [BR:br08330]
 Antiviral
  DG01889  Non-nucleoside reverse transcriptase inhibitor (NNRTI)
   D00435  Nevirapine
  DG03107  Anti-HIV agent
   DG01656  HIV reverse transcriptase inhibitor
    D00435  Nevirapine
 Metabolizing enzyme substrate
  DG02919  CYP2B6 substrate
   D00435  Nevirapine
  DG01644  CYP2D6 substrate
   D00435  Nevirapine
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D00435  Nevirapine
Drug classes [BR:br08332]
 Antiviral
  DG03107  Anti-HIV agent
   D00435  Nevirapine
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   HIV reverse transcriptase inhibitor
    D00435  Nevirapine (JAN/USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Genome replication inhibitor
   HIV reverse transcriptase inhibitor
    D00435  Nevirapine (JAN/USP/INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00435
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00435
Other DBs
CAS: 129618-40-2
PubChem: 9472
PDB-CCD: NVP[PDBj]
NIKKAJI: J420.601K
LinkDB
KCF data

ATOM        20
            1   C5x C    31.3600  -19.3200
            2   C8y C    30.5200  -18.2000
            3   C8y C    30.8700  -16.8700
            4   N1y N    32.1300  -16.3100
            5   N1x N    32.7600  -19.3200
            6   C8y C    33.3900  -16.9400
            7   C8y C    33.6700  -18.2700
            8   N5x N    29.8200  -15.8900
            9   C8x C    28.4900  -16.3100
            10  C8x C    28.1400  -17.6400
            11  C8x C    29.1900  -18.6200
            12  C8y C    35.0000  -18.6900
            13  C8x C    36.0500  -17.7800
            14  C8x C    35.7700  -16.3800
            15  N5x N    34.4400  -15.9600
            16  O5x O    30.7300  -20.5800
            17  C1y C    32.1300  -14.9100
            18  C1a C    35.2800  -20.0900
            19  C1x C    32.8300  -13.7200
            20  C1x C    31.4300  -13.7200
BOND        23
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    1  16 2
            19    4  17 1
            20   12  18 1
            21   19  20 1
            22   20  17 1
            23   17  19 1

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