| Entry |
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| Name |
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| Formula |
C12H21NO8S
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| Exact mass |
339.0988
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| Mol weight |
339.36
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| Structure |
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| Remark |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AX Other antiepileptics
N03AX11 Topiramate
D00537 Topiramate (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
Anticonvulsants, Other
Topiramate
D00537 Topiramate (JAN/USP/INN)
Antimigraine Agents
Antimigraine Agents, Other
Topiramate
D00537 Topiramate (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
113 Antiepileptics
1139 Others
D00537 Topiramate (JAN/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
D00537 Topiramate
Neuropsychiatric agent
DG03199 Antiepileptic agent
DG01569 AMPA receptor antagonist
D00537 Topiramate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00537 Topiramate
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03199 Antiepileptic agent
D00537 Topiramate
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00537 Topiramate (JAN/USP/INN) <JP/US>
Glutamate (ionotropic), non-NMDA
GRIA
D00537 Topiramate (JAN/USP/INN) <JP/US>
GRIK
D00537 Topiramate (JAN/USP/INN) <JP/US>
Voltage-gated ion channels
Sodium channels
SCN1A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN2A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN3A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN4A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN5A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN8A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN9A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN10A
D00537 Topiramate (JAN/USP/INN) <JP/US>
SCN11A
D00537 Topiramate (JAN/USP/INN) <JP/US>
Calcium channels
CACNA1-L
D00537 Topiramate (JAN/USP/INN) <JP/US>
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA2
D00537 Topiramate (JAN/USP/INN) <JP/US>
CA4
D00537 Topiramate (JAN/USP/INN) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00537
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00537
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 C1z C 25.3309 -17.5267
2 C1y C 24.1301 -18.2229
3 O2x O 26.3691 -18.4490
4 O2x O 25.3309 -16.1287
5 C1y C 22.9236 -17.5267
6 O2x O 24.4261 -19.5802
7 C1z C 25.9517 -19.7949
8 C1x C 24.1242 -15.4269
9 C1y C 22.9178 -16.1287
10 O2x O 21.5952 -17.9559
11 O2x O 21.5894 -15.6996
12 C1z C 20.7716 -16.8307
13 C1a C 19.7739 -15.8271
14 C1a C 19.7739 -17.8108
15 C1b C 26.7114 -17.5267
16 O2a O 27.4075 -16.3202
17 S4a S 28.7937 -16.3202
18 O3c O 28.7881 -17.7123
19 C1a C 25.5910 -21.1411
20 C1a C 27.3454 -19.7949
21 O3c O 30.1874 -16.3202
22 N1a N 28.7937 -14.9265
BOND 24
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 5 10 1
10 9 11 1
11 10 12 1
12 12 13 1
13 12 14 1
14 6 7 1
15 8 9 1
16 11 12 1
17 15 16 1
18 16 17 1
19 17 18 2
20 1 15 1 #Down
21 7 19 1
22 7 20 1
23 17 21 2
24 17 22 1
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