| Entry |
|
|---|
| Name |
Methoxyflurane (USP/INN);
Penthrane (TN) |
|---|
| Formula |
C3H4Cl2F2O
|
|---|
| Exact mass |
163.9607
|
|---|
| Mol weight |
164.96
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02028 Inhalational anaesthetics
DG01994 Halogenated hydrocarbons
Metabolizing enzyme substrate
DG02855 CYP2E1 substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Anesthetic (inhalation) |
|---|
| Comment |
Halogenated alkane derivative
|
|---|
| Metabolism |
Enzyme: CYP2E1 [HSA: 1571], CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02B OTHER ANALGESICS AND ANTIPYRETICS
N02BG Other analgesics and antipyretics
N02BG09 Methoxyflurane
D00544 Methoxyflurane (USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02028 Inhalational anaesthetics
DG01994 Halogenated hydrocarbons
D00544 Methoxyflurane
Metabolizing enzyme substrate
DG02855 CYP2E1 substrate
D00544 Methoxyflurane
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00544 Methoxyflurane
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00544
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 8
1 C1d C 25.7016 -18.6729
2 C1c C 24.4893 -19.3723
3 O2a O 26.9138 -19.3723
4 X F 25.7016 -17.2742
5 X F 25.6957 -20.0774
6 X Cl 23.2771 -18.6729
7 X Cl 24.4952 -20.7711
8 C1a C 28.1259 -18.6729
BOND 7
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 1
7 3 8 1
|
|---|
