| Entry |
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| Name |
Diphenylpyraline hydrochloride (JAN);
Hispril (TN);
Vena (TN) |
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| Formula |
C19H23NO. HCl
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| Exact mass |
317.1546
|
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| Mol weight |
317.85
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| Structure |
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| Simcomp |
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
Respiratory system agent
DG01616 Xanthine derivative
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| Remark |
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| Efficacy |
Antiallergic, H1 receptor antagonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
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| Interaction |
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA07 Diphenylpyraline
D01172 Diphenylpyraline hydrochloride (JAN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for otolaryngologic use
69 Oral medicine for nasal inflammation
D01172 Diphenylpyraline hydrochloride (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Diphenylpyraline
D01172 Diphenylpyraline hydrochloride (JAN)
Third-class OTC drugs
Inorganic and organic chemicals
Diphenylpyraline
D01172 Diphenylpyraline hydrochloride (JAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01094 Diphenylpyraline
D01172 Diphenylpyraline hydrochloride
Respiratory system agent
DG01616 Xanthine derivative
DG01094 Diphenylpyraline
D01172 Diphenylpyraline hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D01172 Diphenylpyraline hydrochloride (JAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01094 Diphenylpyraline
Respiratory system agent
DG01616 Xanthine derivative
DG01094 Diphenylpyraline
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 C8x C 15.8965 -18.3777
2 C8x C 15.8965 -19.7781
3 C8x C 17.1122 -20.4783
4 C8x C 18.3208 -19.7781
5 C8y C 18.3208 -18.3777
6 C8x C 17.1122 -17.6775
7 C1c C 19.5341 -17.6783
8 C8y C 20.7462 -18.3795
9 O2a O 19.5351 -16.2779
10 C8x C 20.7398 -19.7779
11 C8x C 21.9519 -20.4789
12 C8x C 23.1653 -19.7798
13 C8x C 23.1663 -18.3794
14 C8x C 21.9540 -17.6782
15 C1y C 20.7485 -15.5788
16 C1x C 21.9589 -16.2788
17 C1x C 23.1722 -15.5796
18 N1y N 23.1733 -14.1792
19 C1x C 21.9609 -13.4780
20 C1x C 20.7478 -14.1773
21 C1a C 24.3866 -13.4799
22 X Cl 27.6442 -16.9632
BOND 23
1 4 5 1
2 5 6 2
3 6 1 1
4 8 10 2
5 10 11 1
6 11 12 2
7 12 13 1
8 13 14 2
9 14 8 1
10 9 15 1
11 5 7 1
12 7 8 1
13 1 2 2
14 7 9 1
15 15 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 15 1
21 2 3 1
22 18 21 1
23 3 4 2
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