KEGG   DRUG: D06330Help
Entry
D06330                      Drug                                   

Name
Xanomeline (USAN)
Formula
C14H23N3OS
Exact mass
281.1562
Mol weight
281.4169
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Alzheimer's disease treatment [cholinergic agent]
Remark
Same as: 
Target
muscarinic cholinergic receptor M1, M4 agonist [HSA:1128 1132] [KO:K04129 K04132]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor M1 [HSA:1128] [KO:K04129]
     Xanomeline
      D06330  Xanomeline (USAN)
    muscarinic cholinergic receptor M4 [HSA:1132] [KO:K04132]
     Xanomeline
      D06330  Xanomeline (USAN)
BRITE hierarchy
Other DBs
CAS: 
131986-45-3
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8y C    13.3700   -7.3500
            2   C8y C    14.7700   -7.3500
            3   N5x N    15.2026   -6.0185
            4   S2x S    14.0700   -5.1956
            5   N5x N    12.9374   -6.0185
            6   O2a O    12.6700   -8.5624
            7   C2y C    15.4700   -8.5624
            8   C1x C    15.4700   -9.9624
            9   N1y N    16.6824  -10.6624
            10  C1x C    17.8949   -9.9624
            11  C1x C    17.8949   -8.5624
            12  C2x C    16.6824   -7.8624
            13  C1b C    11.4576   -7.8400
            14  C1b C    10.2451   -8.5400
            15  C1b C     9.0327   -7.8400
            16  C1b C     7.8203   -8.5400
            17  C1b C     6.6078   -7.8400
            18  C1a C     5.3954   -8.5400
            19  C1a C    16.6821  -12.0398
BOND        20
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 1
            5     1   5 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    7  12 2
            14    6  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20    9  19 1

» Japanese version   » Back

DBGET integrated database retrieval system