KEGG   DRUG: Lapuleucel-T
Entry
D06610                      Drug                                   
Name
Lapuleucel-T (USAN);
APC 8024;
Neuvenge (TN)
Class
Antineoplastic
 DG01918  Tyrosine kinase inhibitor
  DG01917  Receptor tyrosine kinase inhibitor
   DG03158  HER2 inhibitor
Efficacy
Antineoplastic, Receptor tyrosine kinase inhibitor
  Type
Cellular therapy product
Comment
Treatment of cancers over-expressing HER2/neu
Product is a specific active immunotherapeutic composed of antigen-loaded autologous antigen presenting cells designed to stimulate a T cell immune response specific for the tumor-associated antigen HER2/neu
Target
ERBB2 (HER2, CD340) [HSA:2064] [KO:K05083]
  Pathway
hsa04012  ErbB signaling pathway
hsa05200  Pathways in cancer
Interaction
Brite
Drug groups [BR:br08330]
 Antineoplastic
  DG01918  Tyrosine kinase inhibitor
   DG01917  Receptor tyrosine kinase inhibitor
    DG03158  HER2 inhibitor
     D06610  Lapuleucel-T
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   EGFR family
    ERBB2 (HER2, CD340)
     D06610  Lapuleucel-T (USAN)
Other DBs
CAS: 845680-07-1
PubChem: 47208261
LinkDB

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