KEGG   DRUG: D07445Help
Entry
D07445                      Drug                                   

Name
Amfetamine (INN);
Amphetamine;
Amfetamin (TN)
Formula
C9H13N
Exact mass
135.1048
Mol weight
135.2062
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Psychostimulant
Remark
Same as: 
ATC code: 
Drug group: 
Target
noradrenalin transporter inhibitor [HSA:6530] [KO:K05035];
dopamine transporter inhibitor [HSA:6531] [KO:K05036];
serotonin transporter inhibitor [HSA:6532] [KO:K05037]
  Pathway
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
hsa05031  Amphetamine addiction  
 
Interaction
Drug interaction
Structure map
Neurotransmitter transporter inhibitors
Other map
Amphetamine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA01 Amfetamine
      D07445  Amfetamine (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Amfetamine
      D07445  Amfetamine (INN)
    SLC6A3 (dopamine transporter)
     Amfetamine
      D07445  Amfetamine (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2D6
   Amfetamine
    D07445  Amfetamine (INN)
BRITE hierarchy
Other DBs
CAS: 
300-62-9
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        10
            1   C8y C    18.0426  -15.4812
            2   C8x C    16.8566  -14.7835
            3   C8x C    18.0426  -16.8766
            4   C1b C    19.2287  -14.7835
            5   C8x C    15.6008  -15.4812
            6   C8x C    16.8566  -17.5742
            7   C1c C    20.4845  -15.4812
            8   C8x C    15.6008  -16.8766
            9   N1a N    21.6705  -14.7835
            10  C1a C    20.4845  -16.8766
BOND        10
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     7   9 1
            9     7  10 1
            10    6   8 1

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