KEGG   DRUG: D07661Help
Entry
D07661                      Drug                                   

Name
Cerivastatin (INN)
Formula
C26H34FNO5
Exact mass
459.2421
Mol weight
459.5503
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihyperlipidemic
Remark
Same as: 
ATC code: 
Drug group: 
Target
hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor [HSA:3156] [KO:K00021]
  Pathway
hsa00900  Terpenoid backbone biosynthesis  
 
Metabolism
Enzyme: CYP2C8 [HSA:1558], CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
HMG-CoA reductase inhibitors
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AA HMG CoA reductase inhibitors
     C10AA06 Cerivastatin
      D07661  Cerivastatin (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase
    Cerivastatin
     D07661  Cerivastatin (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2C8
   Cerivastatin
    D07661  Cerivastatin (INN)
  CYP3A4
   Cerivastatin
    D07661  Cerivastatin (INN)
BRITE hierarchy
Other DBs
CAS: 
145599-86-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        33
            1   C8y C    21.7700  -17.8500
            2   C8y C    21.7700  -19.3200
            3   C8y C    20.5100  -17.2200
            4   C8y C    22.9600  -17.1500
            5   C8y C    20.5100  -20.0200
            6   C2b C    22.9600  -19.9500
            7   C8y C    19.3200  -17.9200
            8   C1b C    20.5100  -15.7500
            9   C8x C    24.1500  -17.8500
            10  C8x C    22.9600  -15.7500
            11  N5x N    19.3200  -19.3200
            12  C1c C    20.5100  -21.4200
            13  C2b C    24.1500  -19.2500
            14  C1c C    18.1300  -17.2200
            15  O2a O    19.3200  -15.1200
            16  C8x C    25.3400  -17.1500
            17  C8x C    24.1500  -15.0500
            18  C1a C    19.3200  -22.1200
            19  C1a C    21.7700  -22.1200
            20  C1c C    25.3400  -19.9500
            21  C1a C    18.1300  -15.7500
            22  C1a C    16.8700  -17.9200
            23  C1a C    19.3200  -13.7200
            24  C8y C    25.3400  -15.7500
            25  C1b C    26.6000  -19.2500
            26  O1a O    25.3400  -21.3500
            27  X   F    26.6000  -15.0500
            28  C1c C    27.7900  -19.9500
            29  C1b C    28.9800  -19.2500
            30  O1a O    27.7900  -21.3500
            31  C6a C    30.2400  -19.9500
            32  O6a O    30.2400  -21.3500
            33  O6a O    31.4300  -19.2500
BOND        34
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     4  10 1
            10    5  11 1
            11    5  12 1
            12    6  13 2
            13    7  14 1
            14    8  15 1
            15    9  16 1
            16   10  17 2
            17   12  18 1
            18   12  19 1
            19   13  20 1
            20   14  21 1
            21   14  22 1
            22   15  23 1
            23   16  24 2
            24   20  25 1
            25   20  26 1 #Down
            26   24  27 1
            27   25  28 1
            28   28  29 1
            29   28  30 1 #Down
            30   29  31 1
            31   31  32 2
            32   31  33 1
            33    7  11 2
            34   17  24 1

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