KEGG   DRUG: D08187Help
Entry
D08187                      Drug                                   

Name
Metamfetamine (INN);
Methamphetamine
Formula
C10H15N
Exact mass
149.1204
Mol weight
149.2328
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypotensive;
Sympathomimetic;
Psychostimulant
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Indication: Attention Deficit Disorder with Hyperactivity
Target
dopamine transporter inhibitor [HSA:6531] [KO:K05036];
noradrenalin transporter inhibitor [HSA:6530] [KO:K05035];
serotonin transporter inhibitor [HSA:6532] [KO:K05037]
  Pathway
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA03 Metamfetamine
      D08187  Metamfetamine (INN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Amphetamines
   Methamphetamine
    D08187  Metamfetamine (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Metamfetamine
      D08187  Metamfetamine (INN)
    SLC6A3 (dopamine transporter)
     Metamfetamine
      D08187  Metamfetamine (INN)
BRITE hierarchy
Other DBs
CAS: 
537-46-2
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        11
            1   C8y C    17.4300  -15.4700
            2   C1b C    18.6200  -14.7700
            3   C8x C    16.1700  -14.7700
            4   C8x C    17.4300  -16.8700
            5   C1c C    19.8100  -15.4700
            6   C8x C    14.9800  -15.4700
            7   C8x C    16.1700  -17.5700
            8   N1b N    21.0000  -14.7700
            9   C1a C    19.8100  -16.8700
            10  C8x C    14.9800  -16.8700
            11  C1a C    22.2600  -15.4700
BOND        11
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     4   7 2
            7     5   8 1
            8     5   9 1 #Up
            9     6  10 2
            10    8  11 1
            11    7  10 1

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