| Entry |
|
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| Name |
Rebastinib Tosylate (USAN) |
|---|
| Formula |
C30H28FN7O3. C7H8O3S
|
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| Exact mass |
725.2432
|
|---|
| Mol weight |
725.7884
|
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| Structure |
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| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Tyrosine kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01368 Rebastinib
D10399 Rebastinib Tosylate
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
TIE family
TEK (TIE2, CD202)
D10399 Rebastinib Tosylate (USAN)
Non-receptor tyrosine kinases
ABL family
BCR-ABL [HSA_VAR:25v1]
D10399 Rebastinib Tosylate (USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01368 Rebastinib
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 52
1 N5x N 12.4935 -13.7495
2 C8y C 12.4935 -12.3537
3 C8x C 13.6799 -11.6558
4 C8y C 14.9362 -12.3537
5 C8x C 14.9362 -13.7495
6 C8x C 13.6799 -14.4475
7 O2a O 16.1226 -11.6558
8 C8y C 17.3091 -12.3537
9 C8x C 17.3091 -13.7495
10 C8x C 18.5652 -11.6558
11 C8y C 19.7518 -12.3537
12 C8y C 19.7518 -13.7495
13 C8x C 18.5652 -14.4475
14 X F 20.9382 -11.6558
15 O5a O 22.1944 -12.3537
16 C5a C 22.1944 -13.7495
17 N1b N 20.9382 -14.4475
18 N1b N 23.3809 -14.4475
19 C8y C 24.6371 -13.7495
20 N4y N 25.8235 -14.4475
21 N5x N 26.8005 -13.4704
22 C8y C 26.1026 -12.2840
23 C8x C 24.7767 -12.4934
24 C8y C 25.8933 -15.8433
25 C8x C 24.6371 -16.5412
26 C8x C 24.6371 -17.9370
27 C8y C 25.8235 -18.6349
28 C8y C 27.0797 -17.9370
29 C8x C 27.0797 -16.5412
30 N5x N 25.8235 -20.0307
31 C8x C 27.0797 -20.7286
32 C8x C 28.3359 -20.0307
33 C8x C 28.2662 -18.6349
34 C1d C 26.6610 -10.9579
35 C5a C 11.2372 -11.6558
36 N1b N 10.0508 -12.3537
37 C1a C 8.8644 -11.6558
38 O5a O 11.2372 -10.2600
39 C1a C 27.8734 -11.6579
40 C1a C 25.4486 -10.2579
41 C1a C 27.3610 -9.7455
42 C8x C 30.6301 -16.5332
43 C8x C 30.6301 -17.9290
44 C8y C 31.8388 -18.6269
45 C8x C 33.0476 -17.9290
46 C8x C 33.0476 -16.5332
47 C8y C 31.8388 -15.8353
48 S4a S 31.8388 -14.4397
49 C1a C 31.8388 -20.0226
50 O1d O 33.3082 -14.4498
51 O1d O 30.2568 -14.4254
52 O1d O 31.8504 -13.0368
BOND 56
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 8 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 9 13 2
15 11 14 1
16 15 16 2
17 16 17 1
18 12 17 1
19 16 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 2
24 22 23 1
25 19 23 2
26 20 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 24 29 1
33 27 30 1
34 30 31 2
35 31 32 1
36 32 33 2
37 28 33 1
38 22 34 1
39 2 35 1
40 35 36 1
41 36 37 1
42 35 38 2
43 34 39 1
44 34 40 1
45 34 41 1
46 42 43 2
47 43 44 1
48 44 45 2
49 45 46 1
50 46 47 2
51 42 47 1
52 47 48 1
53 44 49 1
54 48 50 2
55 48 51 2
56 48 52 1
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