Entry |
|
Name |
Eleclazine (USAN/INN) |
Formula |
C21H16F3N3O3
|
Exact mass |
415.1144
|
Mol weight |
415.36
|
Structure |
|
Efficacy |
Antiarrhythmic, Anti-ischemic, Sodium channel blocker |
Target |
|
Pathway |
hsa04261 | Adrenergic signaling in cardiomyocytes |
|
Brite |
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D11155 Eleclazine (USAN/INN)
SCN2A
D11155 Eleclazine (USAN/INN)
SCN3A
D11155 Eleclazine (USAN/INN)
SCN4A
D11155 Eleclazine (USAN/INN)
SCN5A
D11155 Eleclazine (USAN/INN)
SCN8A
D11155 Eleclazine (USAN/INN)
SCN9A
D11155 Eleclazine (USAN/INN)
SCN10A
D11155 Eleclazine (USAN/INN)
SCN11A
D11155 Eleclazine (USAN/INN)
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 30
1 C8y C 19.5300 -14.9100
2 C5x C 20.7900 -15.5400
3 N1y N 22.0500 -14.9800
4 C1x C 22.4000 -13.6500
5 C8y C 19.3200 -13.5100
6 C1x C 21.6300 -12.4600
7 O2x O 20.1600 -12.4600
8 O5x O 20.7900 -16.9400
9 C8x C 18.4800 -15.8200
10 C8y C 17.1500 -15.3300
11 C8x C 16.9400 -14.0000
12 C8x C 17.9900 -13.0900
13 C8y C 16.1000 -16.3100
14 C8x C 16.3800 -17.7100
15 C8x C 15.3300 -18.6200
16 C8y C 14.0000 -18.1300
17 C8x C 13.7200 -16.7300
18 C8x C 14.7700 -15.8200
19 O2a O 12.9500 -19.0400
20 C1d C 11.6200 -18.6200
21 X F 10.2900 -18.2700
22 X F 11.2700 -19.9500
23 X F 11.9700 -17.2900
24 C1b C 23.2400 -15.6800
25 C8y C 24.4300 -14.9800
26 N5x N 24.4300 -13.5800
27 C8x C 25.6200 -12.8800
28 C8x C 26.9500 -13.5800
29 C8x C 26.8800 -14.9800
30 N5x N 25.6200 -15.6800
BOND 33
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 2 8 2
9 1 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 5 12 2
14 10 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 13 18 1
21 16 19 1
22 19 20 1
23 20 21 1
24 20 22 1
25 20 23 1
26 24 25 1
27 24 3 1
28 25 26 2
29 26 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 25 30 1
|