KEGG   ORTHOLOGY: K00668
Entry
K00668                      KO                                     
Symbol
FAS1
Name
fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]
Pathway
map00061  Fatty acid biosynthesis
map01100  Metabolic pathways
map01212  Fatty acid metabolism
Module
M00082  Fatty acid biosynthesis, initiation
M00083  Fatty acid biosynthesis, elongation
Reaction
R01404  acyl-[acyl-carrier protein]:NADP+ oxidoreductase
R01624  acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase
R01626  malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase
R04428  (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase
R04430  butyryl-[acp]:NADP+ trans-2-oxidoreductase
R04535  (3R)-3-hydroxydecanoyl-[acyl-carrier-protein] hydro-lyase
R04537  (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase
R04544  (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase
R04568  (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] hydro-lyase
R04725  dodecanoyl-[acp]:NADP+ trans-2-oxidoreductase
R04954  (3R)-3-hydroxyhexanoyl-[acyl-carrier-protein] hydro-lyase
R04956  hexanoyl-[acp]:NADP+ trans-2-oxidoreductase
R04959  octanoyl-[acp]:NADP+ trans-2-oxidoreductase
R04962  decanoyl-[acp]:NADP+ trans-2-oxidoreductase
R04965  (3R)-3-hydroxydodecanoyl-[acyl-carrier-protein] hydro-lyase
R04967  tetradecanoyl-[acp]:NADP+ trans-2-oxidoreductase
R04970  hexadecanoyl-[acp]:NADP+ trans-2-oxidoreductase
R05190  acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing)
R10700  palmitoyl-[acp]:CoA S-palmitoyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K00668  FAS1; fatty acid synthase subunit beta, fungi type
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K00668  FAS1; fatty acid synthase subunit beta, fungi type
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.86  fatty-acyl-CoA synthase system
     K00668  FAS1; fatty acid synthase subunit beta, fungi type
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Yeast type
   K00668  FAS1; fatty acid synthase subunit beta, fungi type
Other DBs
GO: 0004321
Genes
SCE: YKL182W(FAS1)
SEUB: DI49_3200
SPAO: SPAR_K00390
AGO: AGOS_AER085C
ERC: Ecym_3239
KLA: KLLA0_B02717g
KMX: KLMA_40526(FAS1)
LTH: KLTH0D15070g
VPO: Kpol_1055p60
ZRO: ZYRO0B13068g
CGR: CAGL0D00528g
NCS: NCAS_0J01680(NCAS0J01680)
NDI: NDAI_0J02670(NDAI0J02670)
TPF: TPHA_0B02040(TPHA0B02040)
TBL: TBLA_0I03120(TBLA0I03120)
TGB: HG536_0E02010
TDL: TDEL_0E00900(TDEL0E00900)
KAF: KAFR_0A05730(KAFR0A05730)
KNG: KNAG_0B06300(KNAG0B06300)
ZMK: HG535_0B06760
PPA: PAS_chr1-1_0008
DHA: DEHA2B08140g
PIC: PICST_85125(FAS1)
PGU: PGUG_02173
SPAA: SPAPADRAFT_138494
LEL: PVL30_004679(FAS1)
CAL: CAALFM_C500190CA(FAS1)
CTP: CTRG_05241
COT: CORT_0E04830
CDU: CD36_50220(FAS1)
CTEN: CANTEDRAFT_107026
YLI: YALI0B15059g
CLU: CLUG_03422
CLUS: A9F13_01g07634
CAUR: CJI96_0001346
SLB: AWJ20_861(FAS1)
PKZ: C5L36_0A10650
BNN: FOA43_003644(FAS1)
BBRX: BRETT_004505(FAS1_1) BRETT_004531(FAS1_2)
OPA: HPODL_04992
SLUD: SCDLUD_004286
NCR: NCU07307(cel-2)
NTE: NEUTE1DRAFT61255(NEUTE1DRAFT_61255)
SMP: SMAC_00840
PAN: PODANSg3685 PODANSg8559
PBEL: QC761_123300(FAS1_1) QC761_207300
PPSD: QC762_123300(FAS1_1) QC762_207300
PPSP: QC763_123300(FAS1_1) QC763_207300
PPSA: QC764_123300(FAS1_1) QC764_207300
TTT: THITE_2122457
MTM: MYCTH_2310228
CTHR: CTHT_0037750
MGR: MGG_04118
PPEI: PpBr36_04604
PGRI: PgNI_05164 PgNI_06784
TMN: UCRPA7_6807
SSCK: SPSK_04790
FGR: FGSG_05322 FGSG_11656
FPU: FPSE_07168 FPSE_07818
FPOA: FPOAC1_008361
FVN: FVRRES_08932
FVR: FVEG_04242
FOX: FOXG_06392 FOXG_14342 FOXG_15138
NHE: NECHADRAFT_64009
FFC: NCS54_01273000 NCS54_01495800
FKR: NCS57_01236400
FMU: J7337_004245
TRE: TRIREDRAFT_78591
TRR: M419DRAFT_98783
MAW: MAC_02878 MAC_06765
MAJ: MAA_01138
PCHM: VFPPC_03576
CMT: CCM_02997
AMUS: LMH87_006937
PLJ: VFPFJ_00702
PTKZ: JDV02_007947(FAS1_2)
VAL: VDBG_01018
VDA: VDAG_00631
CFJ: CFIO01_03118
CLUP: CLUP02_17680
CHIG: CH63R_09768 CH63R_13998
SAPO: SAPIO_CDS7371
ELA: UCREL1_2864 UCREL1_3666
PFY: PFICI_02555 PFICI_04683 PFICI_09703
SSL: SS1G_13073
BFU: BCIN_01g00450
MBE: MBM_00559
PSCO: LY89DRAFT_624908 LY89DRAFT_784300
GLZ: GLAREA_01152 GLAREA_08470
ANI: ANIA_03381 ANIA_07814 ANIA_07873 ANIA_09408
AFM: AFUA_3G04220
ACT: ACLA_060580 ACLA_093760
NFI: NFIA_006490
AOR: AO090010000108 AO090010000156 AO090011000040 AO090026000013 AO090124000084
ANG: An01g00050 An08g10860 An09g01740 An10g00650 An12g01990
AFV: AFLA_006307 AFLA_007399 AFLA_009127 AFLA_013646 AFLA_013700
ALUC: AKAW2_20202A(FAS1) AKAW2_40150S AKAW2_52045S AKAW2_71015A AKAW2_81152S
ACHE: ACHE_40272A(FAS1)
APUU: APUU_20049S APUU_31411A APUU_50289S(FAS1)
PCS: N7525_000072 N7525_007667
PDP: PDIP_67930 PDIP_87680
POU: POX_c04753 POX_e06170 POX_g09186
TMF: EYB26_005505 EYB26_006384 EYB26_007408 EYB26_009147
TRG: TRUGW13939_07283 TRUGW13939_10098
CIM: CIMG_08479 CIMG_08565
CPW: CPC735_061460 CPC735_062230
URE: UREG_02554 UREG_04458
PBL: PAAG_01524
PBN: PADG_00255
ABE: ARB_02752 ARB_06046
TVE: TRV_06188 TRV_06922
AJE: HCAG_07637
BGH: BDBG_09189
PNO: SNOG_01108 SNOG_02167 SNOG_09091
PTE: PTT_02058 PTT_10815
BZE: COCCADRAFT_113337 COCCADRAFT_7010
BSC: COCSADRAFT_235908
BOR: COCMIDRAFT_1000
AALT: CC77DRAFT_928877
ARAB: EKO05_0004891
ZTR: MYCGRDRAFT_69244
PFJ: MYCFIDRAFT_53243
FFU: CLAFUR5_10726 CLAFUR5_14276
CBET: CB0940_02992 CB0940_06562
BCOM: BAUCODRAFT_151421 BAUCODRAFT_62139
NPA: UCRNP2_2698 UCRNP2_7996
SPO: SPAC926.09c(fas1)
SOM: SOMG_04610(fas1)
CNE: CNE04370
CNB: CNBE4370
CNG: CNAG_02099
CGI: CGB_E5660W
TMS: TREMEDRAFT_40511
TASA: A1Q1_06630
CCAC: CcaHIS019_0211180(CcaverHIS019_0211180)
TVS: TRAVEDRAFT_149581 TRAVEDRAFT_41081
DSQ: DICSQDRAFT_80488
PCO: PHACADRAFT_206686
SHS: STEHIDRAFT_165793
HIR: HETIRDRAFT_433870
PSQ: PUNSTDRAFT_137436 PUNSTDRAFT_143350
ADL: AURDEDRAFT_112733
FME: FOMMEDRAFT_17335
GTR: GLOTRDRAFT_112049
RSX: RhiXN_03112
LBC: LACBIDRAFT_296983(FAS-2)
CCI: CC1G_07064
ABP: AGABI1DRAFT61049(AGABI1DRAFT_61049)
ABV: AGABI2DRAFT217954(AGABI2DRAFT_217954)
PCUB: JR316_0005820
MRR: Moror_12902
MORE: E1B28_011100
SCM: SCHCO_01176814(SCHCODRAFT_01176814) SCHCO_0235165(SCHCODRAFT_0235165) SCHCO_02627311(SCHCODRAFT_02627311)
CPUT: CONPUDRAFT_71103
SLA: SERLADRAFT_449191
WSE: WALSEDRAFT_31561
WIC: J056_004245
UMA: UMAG_06460 UMAG_10339
PFP: PFL1_00007(fas2) PFL1_04986
SGRA: EX895_002632 EX895_005623
PGR: PGTG_06184 PGTG_06788
PTRC: PtA15_8A197
PSTR: Pst134EA_015299 Pst134EA_015306
MLR: MELLADRAFT_115404 MELLADRAFT_79679
ACAN: ACA1_069690
PIF: PITG_10922 PITG_10926 PITG_18025
PSOJ: PHYSODRAFT_324166 PHYSODRAFT_341458 PHYSODRAFT_478148 PHYSODRAFT_556584
SPAR: SPRG_21373
LKM: EFP84_19320
 » show all
Reference
PMID:3528750
  Authors
Schweizer M, Roberts LM, Holtke HJ, Takabayashi K, Hollerer E, Hoffmann B, Muller G, Kottig H, Schweizer E
  Title
The pentafunctional FAS1 gene of yeast: its nucleotide sequence and order of the catalytic domains.
  Journal
Mol Gen Genet 203:479-86 (1986)
DOI:10.1007/BF00422073
  Sequence
[sce:YKL182W]
LinkDB

KEGG   ORTHOLOGY: K00667
Entry
K00667                      KO                                     
Symbol
FAS2
Name
fatty acid synthase subunit alpha, fungi type [EC:2.3.1.86]
Pathway
map00061  Fatty acid biosynthesis
map01100  Metabolic pathways
map01212  Fatty acid metabolism
Module
M00082  Fatty acid biosynthesis, initiation
M00083  Fatty acid biosynthesis, elongation
Reaction
R04355  acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04533  (3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase
R04534  (3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04536  (3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04543  (3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04566  (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04726  dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04952  butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04953  (3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04957  hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04960  octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04963  decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R04964  (3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
R04968  tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)
R05190  acyl-CoA:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K00667  FAS2; fatty acid synthase subunit alpha, fungi type
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K00667  FAS2; fatty acid synthase subunit alpha, fungi type
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.86  fatty-acyl-CoA synthase system
     K00667  FAS2; fatty acid synthase subunit alpha, fungi type
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Yeast type
   K00667  FAS2; fatty acid synthase subunit alpha, fungi type
Other DBs
GO: 0004321
Genes
PXB: 103941732
SCE: YPL231W(FAS2)
SEUB: DI49_5237
SPAO: SPAR_P00450
AGO: AGOS_AFL138W
ERC: Ecym_2158
KLA: KLLA0_C15983g
KMX: KLMA_70219(FAS2)
LTH: KLTH0G09526g KLTH0H03190g
VPO: Kpol_1002p24
ZRO: ZYRO0E07766g
CGR: CAGL0E06138g
NCS: NCAS_0G01260(NCAS0G01260)
NDI: NDAI_0F01390(NDAI0F01390)
TPF: TPHA_0H01860(TPHA0H01860)
TBL: TBLA_0C02010(TBLA0C02010)
TGB: HG536_0A08260 HG536_0B03070
TDL: TDEL_0A06700(TDEL0A06700) TDEL_0C04130(TDEL0C04130)
KAF: KAFR_0F01200(KAFR0F01200)
KNG: KNAG_0D00890(KNAG0D00890)
ZMK: HG535_0A06580 HG535_0D02420
PPA: PAS_chr1-4_0295
DHA: DEHA2B10032g
PIC: PICST_80966(FAS2)
PGU: PGUG_02105
SPAA: SPAPADRAFT_140888(FAS2)
LEL: PVL30_003728(FAS2)
CAL: CAALFM_C304830CA(FAS2)
CTP: CTRG_02501
COT: CORT_0C01740
CDU: CD36_84800
CTEN: CANTEDRAFT_110568
YLI: YALI0B19382g
CLU: CLUG_04160
CLUS: A9F13_04g03652
CAUR: CJI96_0004975
SLB: AWJ20_164(FAS2)
PKZ: C5L36_0C07500
BNN: FOA43_003890(FAS2)
BBRX: BRETT_000610(FAS2)
OPA: HPODL_04019
SLUD: SCDLUD_001146 SCDLUD_002874
NCR: NCU07308(cel-1)
NTE: NEUTE1DRAFT61252(NEUTE1DRAFT_61252)
SMP: SMAC_00841
PAN: PODANSg3686 PODANSg8560
PBEL: QC761_123310(FAS1_2) QC761_207310
PPSD: QC762_123310(FAS1_2) QC762_207310
PPSP: QC763_123310(FAS1_2) QC763_207310
PPSA: QC764_123310(FAS1_2) QC764_207310
TTT: THITE_2122453
MTM: MYCTH_2310232
CTHR: CTHT_0037740
MGR: MGG_12154
PPEI: PpBr36_04603
PGRI: PgNI_05165 PgNI_06785
TMN: UCRPA7_6808
SSCK: SPSK_04795
FGR: FGSG_00036 FGSG_05321
FPU: FPSE_07169 FPSE_07819
FPOA: FPOAC1_008362 FPOAC1_013747(FpAPS5)
FVN: FVRRES_08933
FVR: FVEG_04241
FOX: FOXG_06391
NHE: NECHADRAFT_72277
FFC: NCS54_01273100
FKR: NCS57_01236300
FMU: J7337_004244
TRE: TRIREDRAFT_48788
TRR: M419DRAFT_35261
MAW: MAC_02884 MAC_06764 MAC_07602
MAJ: MAA_01139 MAA_01642 MAA_10451
PCHM: VFPPC_03577
CMT: CCM_02998
AMUS: LMH87_006936
PLJ: VFPFJ_00704
PTKZ: JDV02_007946(FAS1_1)
VAL: VDBG_01020
VDA: VDAG_00632
CFJ: CFIO01_03119
CLUP: CLUP02_17683
CHIG: CH63R_09523 CH63R_09765 CH63R_13996
SAPO: SAPIO_CDS7370
ELA: UCREL1_2866 UCREL1_3665
PFY: PFICI_02560 PFICI_04684 PFICI_09706
SSL: SS1G_13074
BFU: BCIN_01g00440(Bcfas2)
MBE: MBM_00558
PSCO: LY89DRAFT_624910 LY89DRAFT_650084
GLZ: GLAREA_01153 GLAREA_08471
ANI: ANIA_03380 ANIA_07815 ANIA_07880 ANIA_09407
AFM: AFUA_3G04210
ACT: ACLA_060590 ACLA_093750
NFI: NFIA_006480
AOR: AO090010000107 AO090010000171 AO090011000046 AO090026000012 AO090124000083
ANG: An01g00060 An08g10930 An09g02010 An10g00630 An12g01980
AFV: AFLA_006308 AFLA_007408 AFLA_009128 AFLA_013645 AFLA_013717
ALUC: AKAW2_20203S(FAS2_1) AKAW2_40162S AKAW2_71016A AKAW2_81151A
ACHE: ACHE_40273S(FAS2)
APUU: APUU_20048A APUU_31412S APUU_50288A(FAS2)
PCS: N7525_000073 N7525_007664
PDP: PDIP_67940 PDIP_87700
POU: POX_c04750 POX_e06168 POX_g09188
TMF: EYB26_005504 EYB26_006385 EYB26_007410 EYB26_009148
TRG: TRUGW13939_07284 TRUGW13939_10099
CIM: CIMG_08477 CIMG_08564
CPW: CPC735_061450 CPC735_062220
URE: UREG_02553 UREG_04459
PBL: PAAG_01525
PBN: PADG_00254
ABE: ARB_02757 ARB_06048
TVE: TRV_06193 TRV_06923
AJE: HCAG_07636
BGH: BDBG_09190
PNO: SNOG_01107 SNOG_02166 SNOG_09089
PTE: PTT_02059 PTT_10814 PTT_18039
BZE: COCCADRAFT_102373 COCCADRAFT_31318
BSC: COCSADRAFT_97659
BOR: COCMIDRAFT_82264
AALT: CC77DRAFT_929241
ARAB: EKO05_0004890
ZTR: MYCGRDRAFT_108403(FAS1)
PFJ: MYCFIDRAFT_212667
FFU: CLAFUR5_10725 CLAFUR5_14275
CBET: CB0940_02991 CB0940_06561
BCOM: BAUCODRAFT_144102 BAUCODRAFT_77435
NPA: UCRNP2_2699 UCRNP2_3239 UCRNP2_4858 UCRNP2_7999
TML: GSTUM_00002095001
SPO: SPAC4A8.11c(fas2)
SOM: SOMG_03675(fas2)
CNE: CNE04360
CNB: CNBE4360
CNG: CNAG_02100
CGI: CGB_E5650C CGB_E5660W
CDEU: CNBG_5248
TMS: TREMEDRAFT_40511 TREMEDRAFT_45355
TASA: A1Q1_06630 A1Q1_06631
CCAC: CcaHIS019_0211170(fas2)
TVS: TRAVEDRAFT_149581
DSQ: DICSQDRAFT_80488
PCO: PHACADRAFT_206686
SHS: STEHIDRAFT_165793
HIR: HETIRDRAFT_433870
PSQ: PUNSTDRAFT_137436 PUNSTDRAFT_143350
ADL: AURDEDRAFT_112733
FME: FOMMEDRAFT_17335
GTR: GLOTRDRAFT_112049
LBC: LACBIDRAFT_296983(FAS-2)
CCI: CC1G_07064
ABP: AGABI1DRAFT61049(AGABI1DRAFT_61049)
ABV: AGABI2DRAFT217954(AGABI2DRAFT_217954)
PCUB: JR316_0005820
MRR: Moror_12902
MORE: E1B28_011100
SCM: SCHCO_01176814(SCHCODRAFT_01176814) SCHCO_0235165(SCHCODRAFT_0235165) SCHCO_02627311(SCHCODRAFT_02627311)
CPUT: CONPUDRAFT_71103
SLA: SERLADRAFT_449191
WSE: WALSEDRAFT_31561
WIC: J056_004245
UMA: UMAG_06460 UMAG_10339
PFP: PFL1_00007(fas2) PFL1_04986
SGRA: EX895_005623
PGR: PGTG_06788 PGTG_21688
PTRC: PtA15_18A140 PtA15_5A843
PSTR: Pst134EA_009828
MLR: MELLADRAFT_45383
ACAN: ACA1_069690
PIF: PITG_10922 PITG_10926 PITG_18025
PSOJ: PHYSODRAFT_478148 PHYSODRAFT_556584
SPAR: SPRG_21373
MAUB: MAUB_47630
TBW: NCTC13354_01644(fabF)
LKM: EFP84_19320
 » show all
Reference
PMID:2900835
  Authors
Mohamed AH, Chirala SS, Mody NH, Huang WY, Wakil SJ
  Title
Primary structure of the multifunctional alpha subunit protein of yeast fatty acid synthase derived from FAS2 gene sequence.
  Journal
J Biol Chem 263:12315-25 (1988)
  Sequence
[sce:YPL231W]
LinkDB

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