Entry
Symbol
miaA, TRIT1
Name
tRNA dimethylallyltransferase [EC:
2.5.1.75 ]
Pathway
map01110 Biosynthesis of secondary metabolites
Reaction
R01122 delta2-isopentenyl-diphosphate:tRNA isopentenyltransferase
Disease
H00891 Combined oxidative phosphorylation deficiency
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00908 Zeatin biosynthesis
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01006 Prenyltransferases
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
Enzymes [BR:ko01000 ]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.75 tRNA dimethylallyltransferase
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
Prenyltransferases [BR:ko01006 ]
Compound prenylation
tRNA dimethylallyltransferase
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
Transfer RNA biogenesis [BR:ko03016 ]
Eukaryotic type
tRNA modification factors
Other tRNA modification factors
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
Prokaryotic type
tRNA modification factors
Other tRNA modification factors
K00791 miaA, TRIT1; tRNA dimethylallyltransferase
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
Leung HC, Chen Y, Winkler ME
Title
Regulation of substrate recognition by the MiaA tRNA prenyltransferase modification enzyme of Escherichia coli K-12.
Journal
Reference
Authors
Golovko A, Hjalm G, Sitbon F, Nicander B
Title
Cloning of a human tRNA isopentenyl transferase.
Journal
Sequence
Reference
Authors
Miyawaki K, Tarkowski P, Matsumoto-Kitano M, Kato T, Sato S, Tarkowska D, Tabata S, Sandberg G, Kakimoto T
Title
Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis.
Journal
Reference
Authors
Connolly DM, Winkler ME
Title
Genetic and physiological relationships among the miaA gene, 2-methylthio-N6-(delta 2-isopentenyl)-adenosine tRNA modification, and spontaneous mutagenesis in Escherichia coli K-12.
Journal
Sequence
LinkDB
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