Entry Symbol PI4KA
Name phosphatidylinositol 4-kinase A [EC:
2.7.1.67 ]
Pathway map04070 Phosphatidylinositol signaling system
Module M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Reaction R03361 ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase
Disease H00266 Hereditary spastic paraplegia
H02331 Gastrointestinal defects and immunodeficiency syndrome
Brite KEGG Orthology (KO) [BR:ko00001 ]ko01000 ]ko04131 ] BRITE hierarchy Other DBs Genes » show all Taxonomy UniProt Reference Authors Bryant KL, Baird B, Holowka D
Title A novel fluorescence-based biosynthetic trafficking method provides pharmacologic evidence that PI4-kinase IIIalpha is important for protein trafficking from the endoplasmic reticulum to the plasma membrane.
Journal Sequence Reference Authors Yoshida S, Ohya Y, Goebl M, Nakano A, Anraku Y
Title A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae.
Journal J Biol Chem 269:1166-72 (1994)
Sequence Reference Authors Jesch SA, Gaspar ML, Stefan CJ, Aregullin MA, Henry SA
Title Interruption of inositol sphingolipid synthesis triggers Stt4p-dependent protein kinase C signaling.
Journal Sequence LinkDB All DBs
