KEGG ORTHOLOGY: K03359

ORTHOLOGY: K03359

Entry

K03359                      KO

Symbol

APC12, CDC26

Name

anaphase-promoting complex subunit 12

Pathway

map04110

Cell cycle

map04111

Cell cycle - yeast

map04113

Meiosis - yeast

map04114

Oocyte meiosis

map04120

Ubiquitin mediated proteolysis

map04914

Progesterone-mediated oocyte maturation

map05166

Human T-cell leukemia virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
   04111 Cell cycle - yeast
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
   04113 Meiosis - yeast
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
   04114 Oocyte meiosis
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
   03036 Chromosome and associated proteins
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   APC/C
    Other subunits
     K03359  APC12, CDC26; anaphase-promoting complex subunit 12
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Sister chromatid separation proteins
   APC/C complex
    K03359  APC12, CDC26; anaphase-promoting complex subunit 12

Genes

HSA:	246184(CDC26)

PTR:	473026(CDC26)

PPS:	103784082(CDC26)

GGO:	109028324(CDC26)

PON:	100174448(CDC26)

NLE:	100588829(CDC26)

HMH:	116475564(CDC26)

MCC:	706165(CDC26)

MCF:	102134859(CDC26)

MTHB:

126937543

MNI:	105487050(CDC26)

CSAB:

103218996(CDC26)

CATY:

105600976(CDC26)

PANU:

103878141(CDC26)

TGE:	112608480(CDC26)

MLEU:

105534820(CDC26)

RRO:	104667867(CDC26)

RBB:	108532163(CDC26)

TFN:	117098812(CDC26)

PTEH:

111550344(CDC26)

CANG:

105517562(CDC26)

CJC:	100391401(CDC26)

CIMI:

108305514(CDC26)

CSYR:

103259672(CDC26)

MMUR:

105873707(CDC26)

LCAT:

123646521(CDC26)

PCOQ:

105807742(CDC26)

OGA:	100949416(CDC26)

MMU:	66440(Cdc26)

MCAL:

110292252(Cdc26)

MPAH:

110323594(Cdc26)

RNO:	366381(Cdc26)

MCOC:

116096104(Cdc26)

ANU:	117708843(Cdc26)

MUN:	110555570(Cdc26)

CGE:	100753813(Cdc26) 100766682

MAUA:

101841726(Cdc26)

PROB:

127224760(Cdc26)

PLEU:

114683729(Cdc26)

MORG:

121433835(Cdc26) 121451121

MFOT:

126493903 126498035 126515294

AAMP:

119817846(Cdc26)

NGI:	103734527(Cdc26)

HGL:	101705159(Cdc26)

CPOC:

100732729(Cdc26)

CCAN:

109684110(Cdc26)

DORD:

105996164(Cdc26)

DSP:	122117749 122122286(Cdc26)

PLOP:

125346823(Cdc26)

NCAR:

124964718

MMMA:

107147686(Cdc26)

OCU:

100358835

OPI:	101524904(CDC26)

TUP:	102469373 102480336(CDC26)

GVR:	103587269(CDC26)

CFA:	481679(CDC26)

CLUD:

112649773(CDC26)

VVP:	112923073(CDC26)

VLG:	121494889(CDC26)

NPO:	129494844(CDC26)

AML:	100476624(CDC26)

UMR:	103678594(CDC26)

UAH:	113266311(CDC26)

UAR:	123788056(CDC26)

ELK:

111145882

LLV:

125083224

MPUF:

101680241(CDC26)

MNP:	132024500(CDC26)

MLK:	131812460(CDC26)

NVS:	122917335(CDC26)

ORO:	101365482(CDC26)

EJU:	114212921(CDC26)

ZCA:	113934368(CDC26)

MLX:	118017792(CDC26) 118017798

NSU:	110581555(CDC26) 110581556

LWW:	102738578(CDC26)

FCA:	101095692(CDC26)

PYU:	121034857(CDC26)

PCOO:

112848515(CDC26)

PBG:	122475385(CDC26)

PVIV:

125150215(CDC26)

LRUF:

124503246

PTG:	102950236(CDC26)

PPAD:

109269957(CDC26)

PUC:

125926997

AJU:

106978358

HHV:	120236502(CDC26)

BTA:	777693(CDC26)

BOM:	102280324(CDC26)

BIU:	109563364(CDC26)

BBUB:

102397540(CDC26)

BBIS:

104985154(CDC26)

CHX:	102170786(CDC26)

OAS:	101108105(CDC26) 101114750

BTAX:

128052686(CDC26)

ODA:	120863368(CDC26) 120876207

CCAD:

122431915(CDC26)

MBEZ:

129542168 129557071(CDC26)

SSC:	100621961(CDC26)

CFR:	102513728(CDC26)

CBAI:

105070746(CDC26)

CDK:	116152716(CDC26)

VPC:	102544263(CDC26)

BACU:

103003395(CDC26)

BMUS:

118896789(CDC26)

LVE:	103084930(CDC26)

OOR:	101269462(CDC26)

PCAD:

102980916(CDC26)

PSIU:

116755137(CDC26)

NASI:

112411191(CDC26)

ECB:	100053266(CDC26)

EPZ:	103565650(CDC26)

EAI:	106822719(CDC26)

MYB:	102242651(CDC26)

MYD:	102768661(CDC26)

MMYO:

118667166(CDC26)

MLF:	102436645(CDC26)

PKL:	118716158(CDC26)

EFUS:

103303921(CDC26)

MNA:	107535457(CDC26)

DRO:	112306358(CDC26)

SHON:

118995937(CDC26)

AJM:	119044925(CDC26)

PDIC:

114503201(CDC26)

PHAS:

123819979(CDC26)

MMF:	118629713(CDC26)

PPAM:

129079334(CDC26)

HAI:	109379352(CDC26)

RFQ:	117031696(CDC26)

PALE:

102882912(CDC26)

PGIG:

120605826(CDC26)

PVP:	105292626(CDC26)

RAY:	107500750(CDC26)

MJV:	108387305(CDC26)

TOD:	119232353(CDC26)

SARA:

101551524(CDC26)

SETR:

126024660(CDC26)

LAV:	100659806(CDC26)

TMU:

101360561

ETF:	101641766(CDC26)

DNM:	101411867(CDC26)

GAS:	123237269(CDC26)

SHR:	100927470(CDC26)

AFZ:

127550806

PCW:	110193688(CDC26)

OAA:	100075534(CDC26)

GGA:	417269(CDC26)

PCOC:

116234141(CDC26)

CJO:	107321604(CDC26)

TPAI:

128079758(CDC26)

LMUT:

125702489(CDC26)

NMEL:

110407118(CDC26)

APLA:

113845436(CDC26)

ACYG:

125181061(CDC26)

CATA:

118257092(CDC26)

AFUL:

116496803(CDC26)

TGU:	100190078(CDC26)

LSR:	110472227(CDC26)

SCAN:

115484585(CDC26)

PMOA:

120507474(CDC26)

OTC:	121337035(CDC26)

PRUF:

121357581(CDC26)

FAB:	101820166(CDC26)

OMA:	130260055(CDC26)

PHI:	102110981(CDC26)

PMAJ:

107212105(CDC26)

CCW:	120410918(CDC26)

ETL:	114068758(CDC26)

SVG:	106855964(CDC26)

MMEA:

130584743(CDC26)

HRT:	120761793(CDC26)

TALA:

122152756(CDC26)

ACHC:

115335353(CDC26)

HLE:	104833993(CDC26)

AGEN:

126052328

GCL:

127023699

SHAB:

115617030(CDC26)

RTD:	128917594(CDC26)

AAM:	106493015(CDC26)

AROW:

112963088(CDC26)

NPD:	112956123(CDC26)

DNE:	112991365(CDC26)

ASN:	102377802(CDC26)

AMJ:	102562333(CDC26)

CPOO:

109313811(CDC26)

GGN:	109292804(CDC26)

PSS:	102447322(CDC26)

CMY:	102943583(CDC26)

CCAY:

125623548(CDC26)

DCC:	119844175(CDC26)

CPIC:

101953141(CDC26)

TST:	117867257(CDC26)

CABI:

116823989(CDC26)

MRV:	120386785(CDC26)

ACS:	100559425(cdc26)

ASAO:

132763936(CDC26)

PVT:	110082954(CDC26)

SUND:

121937233(CDC26)

PBI:	103062667(CDC26)

PMUR:

107302814(CDC26)

CTIG:

120298861(CDC26)

PGUT:

117656246(CDC26)

APRI:

131186138(CDC26)

PTEX:

113443785(CDC26)

NSS:	113424856(CDC26)

VKO:	123035161(CDC26)

PMUA:

114588955(CDC26)

PRAF:

128406022 128406520(CDC26)

ZVI:	118079776 118084086(CDC26) 118093302 118094682

HCG:	128338877(CDC26)

GJA:	107120426(CDC26)

STOW:

125441726(CDC26)

EMC:	129342478(CDC26)

XLA:	108698127(cdc26.L)

XTR:	116408221(cdc26)

NPR:	108789378(CDC26)

RTEM:

120913960(CDC26)

BBUF:

120977335(CDC26)

BGAR:

122919356(CDC26)

MUO:	115472289(CDC26)

GSH:	117368247(CDC26)

DRE:	445501(cdc26)

SRX:	107721636 107743800

SANH:

107663762 107691734

SGH:	107566898 107603191

CCAR:

109088280(cdc26) 109090632

CAUA:

113049813 113082295

CGIB:

127958596 127994437

PTET:

122345361(cdc26)

LROH:

127164999(cdc26)

OMC:	131541549(cdc26)

PPRM:

120472225(cdc26)

RKG:	130086724(cdc26)

MAMB:

125267926(cdc26)

CIDE:

127512808

MASI:

127426987 127439916

TROS:

130548305(cdc26)

TDW:	130419785(cdc26)

MANU:

129440804(cdc26)

IPU:	100528642(cdc26)

IFU:	128603727(cdc26)

PHYP:

113531023(cdc26)

SMEO:

124379007(cdc26)

TFD:	113641385(cdc26)

TVC:	132840745(cdc26)

AMEX:

103024983(cdc26)

CMAO:

118814599(cdc26)

EEE:	113572476(cdc26)

CHAR:

122129540(cdc26)

TRU:	101078078(cdc26)

TFS:	130517291(cdc26)

TNG:	GSTEN00024792G001

LCO:	104937371(cdc26)

NCC:	104952339(cdc26)

EMAC:

134868768(cdc26)

EFO:	125906320(cdc26)

PLEP:

121959943(cdc26)

SLUC:

116037486(cdc26)

ECRA:

117959784(cdc26)

PFLV:

114571526(cdc26)

GAT:	120831784(cdc26)

PPUG:

119226820(cdc26)

AFB:	129102723(cdc26)

CLUM:

117740236(cdc26)

PSWI:

130204966(cdc26)

MSAM:

119892827 119914165(cdc26)

SCHU:

122866111(cdc26)

CUD:	121525523(cdc26)

ALAT:

119029557(cdc26)

MZE:	101480892(cdc26)

ONL:	100699054(cdc26)

OAU:	116322039(cdc26)

OML:	112138594(cdc26)

CSAI:

133451907 133452230 133455526(cdc26)

XMA:	102217578(cdc26)

XCO:	114136975(cdc26)

XHE:	116724211(cdc26)

PRET:

103460432(cdc26)

PFOR:

103130343(cdc26)

PLAI:

106937163(cdc26)

PMEI:

106910516(cdc26)

GAF:	122819760(cdc26)

PPRL:

129356192(cdc26)

CVG:	107098052(cdc26)

CTUL:

119774476(cdc26)

GMU:	124872709(cdc26)

NFU:	107374962(cdc26)

KMR:	108228298(cdc26)

ALIM:

106534585(cdc26)

NWH:	119424960(cdc26)

AOCE:

111564346(cdc26)

MCEP:

124997033(cdc26)

CSEM:

103390359(cdc26)

POV:	109646158(cdc26)

SSEN:

122758261(cdc26)

HHIP:

117771392(cdc26)

HSP:	118125586(cdc26)

SMAU:

118284540(cdc26)

LCF:

108874609

SDU:	111238744(cdc26)

SLAL:

111670249(cdc26)

XGL:	120806049(cdc26)

HCQ:	109525119(cdc26)

SSCV:

125979416

SBIA:

133490526(cdc26)

PEE:	133413512(cdc26)

PTAO:

133489928(cdc26)

BPEC:

110166018(cdc26)

MALB:

109973133(cdc26)

BSPL:

114867129(cdc26)

SJO:	128380345(cdc26)

SASA:

100195816(cdc26) 106567795

STRU:

115159715 115203956(cdc26)

OTW:	112220304 112230798(cdc26)

OMY:	110509682(cdc26) 110523464 118965226

OGO:	124006939(cdc26) 124042259 124047696

ONE:	115121194 115147168(cdc26)

OKI:	109874187(cdc26)

OKE:	118369893 118385477(cdc26)

SALP:

111961742 111963923

SNH:	120020964 120026491

CCLU:

121541571(cdc26)

ELS:	105015133(cdc26)

SFM:	108929862(cdc26)

PKI:	111847449(cdc26)

AANG:

118212530(cdc26)

LOC:	102692310(cdc26)

PSPA:

121306659(cdc26)

ARUT:

117396899 117964687

PSEX:

120542996(cdc26)

LCM:	102364023(CDC26)

CMK:	103182981(cdc26)

RTP:	109921450(cdc26)

CPLA:

122564733(cdc26)

HOC:	132825799(cdc26)

LERI:

129712152(cdc26)

LRJ:	133360183(CDC26)

BFO:

BBEL:

SCLV:

SPU:

LPIC:

APLC:

SKO:

CPII:

AME:

ACER:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

FVI:

CCAL:

NMEA:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

DQU:

CFO:

FEX:

OBO:

LHT:

LBD:

MDL:

TCA:

SOY:

AGRG:

NVL:

DPL:	KGM_216066

CCRN:

RMD:

HVI:

FOC:

TPAL:

ZNE:

BROR:

FCD:

TCF:

DPTE:

DFR:

LGI:	LOTGIDRAFT_190326

OBI:

106869900

OSN:

115217433

OTA:	OT_ostta12g01990

SCE:	YFR036W(CDC26)

SEUB:

DI49_1697

SPAO:

SPAR_F00970

AALT:

CC77DRAFT_1019465

DDI:	DDB_G0293230(cdc26)

DPP:	DICPUDRAFT_31219

DFA:	DFA_10724(cdc26)

NGD:	NGA_0384502

» show all

Reference

PMID:10922056

Authors

Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM

Title

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.

Journal

Proc Natl Acad Sci U S A 97:8973-8 (2000)
DOI:10.1073/pnas.97.16.8973

Sequence

[hsa:246184]

Reference

PMID:1736102

Authors

Araki H, Awane K, Ogawa N, Oshima Y

Title

The CDC26 gene of Saccharomyces cerevisiae is required for cell growth only at high temperature.

Journal

Mol Gen Genet 231:329-31 (1992)
DOI:10.1007/bf00279807

Sequence

[sce:YFR036W]

LinkDB

DBGET integrated database retrieval system