KEGG ORTHOLOGY: K04010

ORTHOLOGY: K04010

Entry

K04010                      KO

Symbol

C5AR1, CD88

Name

C5a anaphylatoxin chemotactic receptor 1

Pathway

map04080

Neuroactive ligand-receptor interaction

map04610

Complement and coagulation cascades

map04613

Neutrophil extracellular trap formation

map04936

Alcoholic liver disease

map05150

Staphylococcus aureus infection

map05171

Coronavirus disease - COVID-19

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
   04613 Neutrophil extracellular trap formation
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
   04090 CD molecules
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Anaphylatoxin
    K04010  C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
CD molecules [BR:ko04090]
Proteins
  K04010  CD88, C5R1; complement component 5 receptor 1 (C5a ligand)

Other DBs

GO:

0004878

Genes

HSA:	728(C5AR1)

PTR:	468931(C5AR1)

PPS:	100975182(C5AR1)

PON:	100455789(C5AR1)

NLE:	100589337(C5AR1)

HMH:	116478286(C5AR1)

MCC:	718056(C5AR1)

MCF:	102122506(C5AR1)

MTHB:

126943482

MNI:	105478605(C5AR1)

CSAB:

103234937(C5AR1)

CATY:

105595203(C5AR1)

PANU:

101024314(C5AR1)

TGE:	112613036(C5AR1)

MLEU:

105531781(C5AR1)

RRO:	104673388(C5AR1)

RBB:	108540047(C5AR1)

TFN:	117091470(C5AR1)

PTEH:

111556087(C5AR1)

CANG:

105501008(C5AR1)

CJC:	100409718(C5AR1)

SBQ:	101034910(C5AR1)

CIMI:

108283846(C5AR1)

CSYR:

103255433(C5AR1)

MMUR:

105869586(C5AR1)

LCAT:

123623900(C5AR1)

PCOQ:

105817587(C5AR1)

OGA:	100945726(C5AR1)

MMU:	12273(C5ar1)

MCAL:

110299315(C5ar1)

MPAH:

110337033(C5ar1)

RNO:	113959(C5ar1)

MCOC:

116100387(C5ar1)

ANU:	117700540(C5ar1)

MUN:	110561320(C5ar1)

CGE:

113837324

MAUA:

101834425(C5ar1)

PROB:

127238800(C5ar1)

PLEU:

114681439(C5ar1)

MORG:

121449996(C5ar1)

MFOT:

126493341

AAMP:

119821147(C5ar1)

NGI:	103724910(C5ar1)

HGL:	101713576(C5ar1)

CPOC:

100135489(C5ar1)

CCAN:

109694074 109697536

DORD:

105998120(C5ar1)

DSP:	122125751(C5ar1)

PLOP:

125338961(C5ar1)

NCAR:

124967614

MMMA:

107151318(C5ar1)

OCU:

100352978

OPI:	101519644(C5AR1)

TUP:	102500766(C5AR1)

GVR:	103583189 103609598

CFA:	442974(C5AR1)

CLUD:

112645243(C5AR1)

VVP:	112931331(C5AR1)

VLG:	121484835 121484841

NPO:	129500426(C5AR1)

AML:	100470118(C5AR1)

UMR:	103657079(C5AR1)

UAH:	113243378(C5AR1)

UAR:	123776271(C5AR1)

ELK:

111160717

LLV:

125089890

MPUF:

101692871(C5AR1)

MNP:	132005322(C5AR1)

MLK:	131817734(C5AR1)

NVS:	122913892(C5AR1)

ORO:	101367254(C5AR1)

EJU:	114197037(C5AR1)

ZCA:	113936629(C5AR1)

MLX:	117998197(C5AR1)

NSU:	110572807(C5AR1)

LWW:	102750538(C5AR1)

FCA:	101098593(C5AR1)

PYU:	121018682(C5AR1)

PCOO:

112851164(C5AR1)

PBG:	122493874(C5AR1)

PVIV:

125153747(C5AR1)

LRUF:

124510980

PTG:	102962094(C5AR1)

PPAD:

109253169(C5AR1)

PUC:

125915684

AJU:

106973630

HHV:	120242817(C5AR1)

BTA:	493645(C5AR1)

BOM:	102284060(C5AR1)

BIU:	109572958(C5AR1)

BBUB:

102400801(C5AR1)

BBIS:

104997735(C5AR1)

CHX:	102178657(C5AR1)

OAS:	101118296(C5AR1)

BTAX:

128063588(C5AR1)

ODA:	120872229(C5AR1)

CCAD:

122420396(C5AR1)

MBEZ:

129546619(C5AR1)

SSC:	100048955(C5AR1)

CFR:	102505946(C5AR1)

CBAI:

105062561(C5AR1)

CDK:	105098917(C5AR1)

VPC:	102534914(C5AR1)

BACU:

103000958(C5AR1)

BMUS:

118885391(C5AR1)

LVE:	103088737(C5AR1)

OOR:	101270207(C5AR1)

DLE:	111180688(C5AR1)

PCAD:

102976859(C5AR1)

ECB:	100065997(C5AR1)

EPZ:	103567448(C5AR1)

EAI:	106845159(C5AR1)

MYB:	102247978(C5AR1)

MYD:

102755212

MMYO:

118652814(C5AR1)

PKL:	118706769(C5AR1)

EFUS:

103297797(C5AR1)

MNA:	107540051(C5AR1)

DRO:	112312961(C5AR1)

SHON:

118996167(C5AR1)

AJM:	119056650(C5AR1)

PHAS:

123823013(C5AR1)

MMF:	118639243(C5AR1)

PPAM:

129082885(C5AR1)

HAI:	109372198(C5AR1)

RFQ:	117035584(C5AR1)

PALE:

102879583(C5AR1)

PGIG:

120617902(C5AR1)

PVP:	105297312(C5AR1)

RAY:	107516012(C5AR1)

MJV:	108398858(C5AR1)

TOD:	119250459(C5AR1)

SARA:

101557429(C5AR1)

SETR:

126027513 126027514 126027516 126027527 126027528 126028584 126028585 126028586 126028588 126028589 126028590 126028591 126028592 126028593

LAV:	100660750(C5AR1)

TMU:

101348527

ETF:	101660270(C5AR1)

DNM:

101413068

MDO:	100020568(C5AR1)

GAS:	123240871(C5AR1)

SHR:	100918726(C5AR1) 105750200

AFZ:

127556252

PCW:	110202379(C5AR1)

OAA:	100090459(C3AR1) 100092664(C5AR1)

GGA:	430484(C5AR1)

PCOC:

MGP:

CJO:

NMEL:

ACYG:

CATA:

AFUL:

LSR:

PMOA:

120511904(C5AR1)

OTC:	121341209(C5AR1)

PRUF:

121364650(C5AR1)

OMA:	130262798(C5AR1)

PHI:

102111852

PMAJ:

107199300

SVG:

106864424

FPG:	101921487(C5AR1)

FCH:

102047388

CLV:	102094460(C5AR1)

EGZ:

104126435

NNI:

104011814

PCRI:

104031483(C5AR1)

PLET:

104618936(C5AR1)

PADL:

103922286(C5AR1)

AFOR:

103893237

ACHC:

115337686 115337690

HALD:

104315718(C5AR1)

AGEN:

126036741

CCRI:

104159872(C5AR1)

CSTI:

104562865

CMAC:

104481129

MUI:	104546001(C5AR1)

BREG:

104638650

FGA:	104077562(C5AR1)

GSTE:

104254845(C5AR1)

LDI:

104343608

OHA:

104329916

SHAB:

115603271(C5AR1)

PGUU:

104469817(C5AR1)

ACAR:

CVF:

CUCA:

TEO:

AAM:	106492577 106492584

AROW:

DNE:

SCAM:

ASN:

AMJ:	102564012(C5AR1)

CMY:	102933214 102933448(C5AR1)

CCAY:

125628115(C5AR1) 125628117

DCC:	119847291 119847292

CPIC:

101947905 101948363(C5AR1)

TST:	117888880(C5AR1)

CABI:

116819223(C5AR1) 116819224

MRV:	120388735(C5AR1)

ACS:	100562629(c5ar1)

ASAO:

132780892(C5AR1)

PVT:	110075705(C5AR1)

SUND:

121915804

PBI:

103051246

PMUR:

107285685(C5AR1)

CTIG:

120316500

TSR:	106541066(C5AR1)

PGUT:

117677619(C5AR1)

APRI:

131204214(C5AR1)

PTEX:

113450313

NSS:

113425573

VKO:

123023255

PMUA:

114603411(C5AR1)

PRAF:

128418170(C5AR1)

ZVI:	118086643(C5AR1)

HCG:	128333214(C5AR1)

GJA:	107106907(C5AR1)

EMC:	129343082(C5AR1)

XLA:	108698596(c5ar1.L) 108700674(c5ar1.S)

XTR:	100379958(c5ar1)

NPR:	108784379 108784403 108784405 108792253

RTEM:

120913551(C5AR1)

BBUF:

120977404

BGAR:

122946215

MUO:	115480065(C5AR1)

GSH:	117364834 117364835

DRE:	100000959(c5ar1) 794255(c3ar1)

SRX:	107709661 107709662 107709669 107717611 107727829 107727922 107733301

SANH:

107653766 107653770 107670597 107692022 107692031 107692493

SGH:	107548977 107548978 107548979 107548980 107560134 107568579 107568580 107568583 107568588 107578154 107602107

CCAR:

109046021 109046343 109060517 109061318 109066200 109071539 109072269 109072270 109075718 109076083 109084439 109089521 109091269 109091542 109098384 109106383 109106384 109112373 109112375

PTET:

122323172 122333865 122333867 122333868 122333869

LROH:

127159338 127160565 127171563 127171565 127171566 127171607 127171781 127180510(c5ar1)

OMC:	131523874(c5ar1) 131547887(c3ar1) 131548377

PPRM:

120459894 120479107

RKG:	130069993(c5ar1) 130094963

MAMB:

125253984(c5ar1) 125254122 125262527 125262536 125262706 125262990

CIDE:

127499827 127499839 127499847 127499955 127520979

MASI:

127416616 127433094 127433099 127433100 127433589 127433967 127433968 127433969 127433971 127433972 127433973 127433977 127456189

TROS:

130546347 130562686(c5ar1)

TDW:	130411835 130435764(c5ar1)

MANU:

129419323(c5ar1) 129446402

IPU:	108264848(c5ar1) 108277390

IFU:	128606993(c5ar1) 128620868

PHYP:

113534755 113544876

SMEO:

124393636 124395742(c5ar1)

TFD:	113638303 113652608 113652609(c5ar1)

TVC:	132851421(c5ar1) 132863589(c3ar1)

AMEX:

103034372 103047806

CMAO:

118818053 118825291

EEE:	113573287 113587920

CHAR:

105899485 105899487 105911740

TRU:

105417034

TFS:	130534477(c5ar1)

TNG:	GSTEN00022090G001

LCO:

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

134879925(c5ar1)

ELY:

117259678

EFO:	125889399(c5ar1)

PLEP:

121943329

SLUC:

116043850

ECRA:

117942056

ESP:	116674478 116687112

PFLV:

114553310

GAT:

120822456

PPUG:

119217494

AFB:	129088787(c5ar1)

CLUM:

117741878

PSWI:

130210606(c5ar1)

MSAM:

SCHU:

CUD:

ALAT:

MZE:	101472992 101473293 101484375

ONL:	100690001 100690266 100690534

OAU:	116330408 116330915 116330919

OLA:

101169056

OML:

112141280

CSAI:

133441601(c5ar1)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

129359066(c5ar1)

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

MCEP:

125013384(c5ar1)

CSEM:

POV:

SSEN:

HHIP:

HSP:	118106506(c5ar1)

SMAU:

118299076(c5ar1)

LCF:	108879410(c5ar1)

SDU:

111222557

SLAL:

111651336

XGL:

120792055

HCQ:	109512823 109512832

SSCV:

125972626

SBIA:

133504779 133504780

PEE:	133404767(c5ar1)

PTAO:

133481919(c5ar1)

BPEC:

110162019

MALB:

109954159 109960378

BSPL:

114868504(c5ar1)

SJO:	128359837(c5ar1) 128380636

SASA:

106568372 106568373 106581080 106612975

STRU:

115148342 115149368 115163527 115206436

OTW:	112257412 112259306 112265602 112267435

OMY:	100136104(c3ar1) 100136191(c5ar) 110504024 110537020

OGO:	123993910 124000080 124000514 124005771

ONE:	115104748 115105959 115136670 115141899

OKI:	109892050 109892384 109905790 109909199

OKE:	118391516 118391736 118397515 118397621

SALP:

111960680 111980302 111981912 111982507

SNH:	120018746 120029045 120044207 120044932

CCLU:

121558596 121568405 121574310 121574312 121574521 121574524 121574526

ELS:	105006441 105029633

SFM:	108924981 108934056

PKI:	111836084 111860455

AANG:

118208829 118213442

LOC:	102689914 102691665

PSPA:

121294565 121303853 121304895 121328378

ARUT:

117398006 117408701 117415285 117973186

PSEX:

120538730 120539721

LCM:	102358515 102360304 102360946 102361200 102361457

RTP:

109924785

CPLA:

122545762 122546485

HOC:	132813883 132813885 132813886 132813888

PMEO:

129596720

CRG:	105317391 109617265

CANU:

128164583 128164585 128164586 128164588 128172955

OED:	125672185 125672191

MMER:

123539804

ATEN:

116306857

» show all

Reference

PMID:2007135

Authors

Boulay F, Mery L, Tardif M, Brouchon L, Vignais P

Title

Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells.

Journal

Biochemistry 30:2993-9 (1991)
DOI:10.1021/bi00226a002

Sequence

[hsa:728]

Reference

PMID:24265019

Authors

Cheng L, Bu H, Portillo JA, Li Y, Subauste CS, Huang SS, Kern TS, Lin F

Title

Modulation of retinal Muller cells by complement receptor C5aR.

Journal

Invest Ophthalmol Vis Sci 54:8191-8 (2013)
DOI:10.1167/iovs.13-12428

Sequence

[hsa:728]

LinkDB

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