KEGG ORTHOLOGY: K04284

ORTHOLOGY: K04284

Entry

K04284                      KO

Symbol

GHSR

Name

growth hormone secretagogue receptor

Pathway

map04024

cAMP signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04935

Growth hormone synthesis, secretion and action

Disease

H00254

Growth hormone deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K04284  GHSR; growth hormone secretagogue receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04284  GHSR; growth hormone secretagogue receptor
09150 Organismal Systems
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    K04284  GHSR; growth hormone secretagogue receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04284  GHSR; growth hormone secretagogue receptor
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Peptide
   Ghrelin
    K04284  GHSR; growth hormone secretagogue receptor

Other DBs

GO:

0001616

TC:	9.A.14.1.6

Genes

HSA:	2693(GHSR)

PTR:	460851(GHSR)

PPS:	100986658(GHSR)

GGO:	101129513(GHSR)

PON:	100441154(GHSR)

NLE:	100607753(GHSR)

HMH:	116480307(GHSR)

MCC:	694587(GHSR)

MCF:	102135014(GHSR)

MTHB:

126948357

MNI:	105465651(GHSR)

CSAB:

103221247(GHSR)

CATY:

105586080(GHSR)

PANU:

100126744(GHSR)

TGE:	112619058(GHSR)

MLEU:

105552584(GHSR)

RRO:	104657166(GHSR)

RBB:	108540408(GHSR)

TFN:	117077138(GHSR)

PTEH:

111543524(GHSR)

CANG:

105510994(GHSR)

CJC:	100396360(GHSR)

SBQ:	101029971(GHSR)

CIMI:

108305195(GHSR)

MMUR:

105855414(GHSR)

LCAT:

123641732(GHSR)

PCOQ:

105806959(GHSR)

OGA:	100958831(GHSR)

MMU:	208188(Ghsr)

MCAL:

110291654(Ghsr)

MPAH:

110320669(Ghsr)

RNO:	84022(Ghsr)

MCOC:

116095018(Ghsr)

ANU:	117707589(Ghsr)

MUN:	110557492(Ghsr)

CGE:	100755255(Ghsr)

MAUA:

101826609(Ghsr)

PROB:

127223196(Ghsr)

PLEU:

114697543(Ghsr)

MORG:

121453028(Ghsr)

MFOT:

126501385

AAMP:

119826916(Ghsr)

NGI:	103739878(Ghsr)

HGL:	101702096(Ghsr)

CPOC:

100731433(Ghsr)

CCAN:

109694744(Ghsr)

DORD:

105985600(Ghsr)

DSP:	122107297(Ghsr)

PLOP:

125351973(Ghsr)

NCAR:

124993493

MMMA:

107149557(Ghsr)

OCU:	100101582(GHSR)

OPI:	101522971(GHSR)

TUP:	102493418(GHSR)

GVR:	103585788(GHSR)

CFA:	100101479(GHSR)

CLUD:

112645968(GHSR)

VVP:	112926676(GHSR)

VLG:	121477312(GHSR)

NPO:	129498395(GHSR)

AML:	100484774(GHSR)

UMR:	103676206(GHSR)

UAH:	113256719(GHSR)

UAR:	123786462(GHSR)

ELK:

111151762

LLV:

125081654

MPUF:

101675017(GHSR)

MNP:	132010082(GHSR)

MLK:	131825874(GHSR)

NVS:	122910483(GHSR)

ORO:	101370855(GHSR)

EJU:	114207056(GHSR)

ZCA:	113918385(GHSR)

MLX:	118000292(GHSR)

NSU:	110591733(GHSR)

LWW:	102744515(GHSR)

FCA:	101083540(GHSR)

PYU:	121033362(GHSR)

PBG:	122492381(GHSR)

PVIV:

125175551(GHSR)

LRUF:

124525928

PTG:	102971081(GHSR)

PPAD:

109275135(GHSR)

PUC:

125921878

AJU:

106990076

HHV:	120234624(GHSR)

BTA:	514203(GHSR)

BOM:	102286831(GHSR)

BIU:	109558036(GHSR)

BBUB:

123465899(GHSR)

BBIS:

104985205(GHSR)

CHX:	102173610(GHSR)

OAS:	443238(GHSR)

BTAX:

128056061(GHSR)

ODA:	120869561(GHSR)

CCAD:

122444931(GHSR)

MBEZ:

129550954(GHSR)

SSC:	397372(GHSR)

CFR:	102505906(GHSR)

CBAI:

105063298(GHSR)

CDK:	105085945(GHSR)

VPC:	102538136(GHSR)

BACU:

102997879(GHSR)

BMUS:

118894501(GHSR)

LVE:	103089904(GHSR)

OOR:	101283330(GHSR)

DLE:	111173956(GHSR)

PCAD:

102992617(GHSR)

PSIU:

116753237(GHSR)

NASI:

112396902(GHSR)

ECB:	100057865(GHSR)

EPZ:	103546357(GHSR)

EAI:	106847553(GHSR)

MYB:	102263465(GHSR)

MYD:	102756866(GHSR)

MMYO:

118675030(GHSR)

MLF:	102442453(GHSR)

PKL:	118724545(GHSR)

EFUS:

103286810(GHSR)

MNA:	107533516(GHSR)

DRO:	112309270(GHSR)

SHON:

118987497(GHSR)

AJM:	119043467(GHSR) 119063963

PDIC:

114515134(GHSR)

PHAS:

123826967(GHSR)

MMF:	118617520(GHSR)

PPAM:

129073376(GHSR)

HAI:	109371669(GHSR)

RFQ:	117012950(GHSR)

PALE:

102885425(GHSR)

PGIG:

120604351(GHSR)

PVP:	105305701(GHSR)

RAY:	107519030(GHSR)

MJV:	108383371(GHSR)

TOD:	119256763(GHSR)

SARA:

101537161(GHSR)

SETR:

126011183(GHSR)

LAV:	100660018(GHSR)

TMU:

101358863

ETF:	101645941(GHSR)

DNM:	101435045(GHSR)

MDO:	100010258(GHSR)

GAS:	123254654(GHSR)

SHR:	100927855(GHSR)

AFZ:

127557732

PCW:	110203279(GHSR)

GGA:	378911(GHSR)

PCOC:

116243392(GHSR)

MGP:	100550294(GHSR)

CJO:	107318307(GHSR)

TPAI:

128082434(GHSR)

LMUT:

125697517(GHSR)

NMEL:

110398961(GHSR)

APLA:

101798856(GHSR)

ACYG:

106032150(GHSR)

CATA:

118253196(GHSR)

AFUL:

116492671(GHSR)

TGU:	100226951(GHSR)

LSR:	110480350(GHSR)

SCAN:

103815296(GHSR)

PMOA:

120504270(GHSR)

OTC:	121336581(GHSR)

PRUF:

121353734(GHSR)

GFR:	102042950(GHSR)

FAB:	101819691(GHSR)

OMA:	130256711(GHSR)

PHI:	102104523(GHSR)

PMAJ:

107208556(GHSR)

CCAE:

111933336(GHSR)

CCW:	104688036(GHSR)

CBRC:

103625090(GHSR)

ETL:	114061189(GHSR)

ZAB:	102062939(GHSR)

ACHL:

103806393(GHSR)

SVG:	106859650(GHSR)

MMEA:

130575495(GHSR)

HRT:	120757094(GHSR)

FPG:	101923022(GHSR)

FCH:	102048496 102050924(GHSR)

CLV:	102090014(GHSR)

EGZ:	104132495(GHSR) 104135982

NNI:	104012929 104022059(GHSR)

PCRI:

104036228(NTSR1)

PLET:

104623534(GHSR) 104625973

EHS:	104513114(GHSR) 104513964

PCAO:

104040549(GHSR) 104052927

ACUN:

113480203 113483421(GHSR)

TALA:

104358434(GHSR) 104359066

PADL:

103919200 103924980(GHSR)

AFOR:

103906174(GHSR)

ACHC:

115333636 115347745(GHSR)

HALD:

104323844(GHSR)

HLE:	104835093(GHSR)

AGEN:

126039521 126050383

GCL:	127019780 127020264

CCRI:

104163804(GHSR) 104166740

CSTI:

104563984(GHSR)

CMAC:

104485443(GHSR)

MUI:	104536949(GHSR)

BREG:

104637431(GHSR) 104637869

FGA:	104076247(GHSR) 104076847

GSTE:

104252545(GHSR) 104256014

LDI:	104343927 104350066(GHSR)

MNB:	103777106(GHSR)

OHA:	104334410(GHSR)

NNT:	104413312(GHSR)

SHAB:

115611680(GHSR)

DPUB:

104301906(GHSR)

PGUU:

104469383(GHSR)

ACAR:

104518686 104531725

CPEA:

104394569(GHSR)

AVIT:

104276063 104276233(GHSR)

CVF:	104283564 104285982(GHSR)

RTD:	128911506(GHSR) 128914770

CUCA:

104060714(GHSR)

TEO:	104382094(GHSR)

BRHI:

104499170(GHSR)

AAM:	106486567(GHSR) 106491123

AROW:

112964120(GHSR) 112966305

NPD:	112952492(GHSR)

TGT:	104571812(GHSR)

DNE:	112980831 112986475(GHSR)

SCAM:

104143324(GHSR) 104152368

ASN:	102373811(GHSR) 102379211

AMJ:	102557623(GHSR) 102566769

CPOO:

109308273(GHSR) 109310902

GGN:	109287752(GHSR) 109300484

PSS:	102450994 102462308(GHSR)

CMY:	102931963 102946258(GHSR)

CCAY:

125642929(GHSR) 125643213

DCC:	119861401 119861435(GHSR)

CPIC:

101931978(GHSR) 101941151

TST:	117882907 117882995(GHSR)

CABI:

116826729(GHSR) 116834710

MRV:	120372274(GHSR)

ACS:	100552910(ghsr) 100563939

ASAO:

132763149 132770504(GHSR)

PVT:	110079061(GHSR)

SUND:

121924766 121937004

PBI:	103056856(GHSR)

PMUR:

107286548(GHSR)

CTIG:

120305861(GHSR)

TSR:

106539928

PGUT:

117678185(GHSR)

APRI:

131201329(GHSR)

PTEX:

113439702(GHSR)

NSS:	113411839(GHSR)

VKO:	123022057 123025656(GHSR)

PMUA:

114589299 114597985(GHSR)

PRAF:

128406901 128414777(GHSR)

ZVI:	118078276 118093943(GHSR)

HCG:	128335427 128351030(GHSR)

GJA:	107110543 107113857(GHSR)

STOW:

125438161(GHSR) 125442941

EMC:	129332769(GHSR) 129341639

XLA:	108698472 108717007(ghsr.L) 108718095(ghsr.S)

XTR:	100497774(ghsr) 108648264

NPR:	108784842(GHSR) 108798882

RTEM:

120914447 120936755(GHSR)

BBUF:

120978107 121000043(GHSR)

BGAR:

122919759 122935947(GHSR)

MUO:	115458281 115474988 115478992(GHSR)

GSH:	117349795 117360294 117367025(GHSR)

DRE:	100332193(ghsrb) 795753(ghsra)

SRX:	107721864 107722546 107725860 107732507 107737948

SANH:

107663640 107680230 107685461 107688542

SGH:	107550603 107572971 107586567 107586810 107590301

CCAR:

109049047 109049508 109059938 109105102 109105612

CAUA:

113041872 113042770 113045922 113065771 113065859 113065948 113069722

CGIB:

127944856 127946492 127951350 128013257 128029025

PTET:

122324615(ghsra) 122330033(ghsrb) 122334597

LROH:

127155479(ghsrb) 127162299 127174994(ghsra)

OMC:	131531673 131533271(ghsrb) 131552527(ghsra)

PPRM:

120471103 120482066(ghsra) 120488144

RKG:	130070952(ghsra) 130072358 130084006(ghsrb)

MAMB:

125251737(ghsra) 125258386(ghsrb) 125260840

CIDE:

127497380 127504883 127505848

MASI:

127419335 127420182 127431627 127434499 127441524 127442298

TROS:

130545243 130547044(ghsrb) 130554650(ghsra)

TDW:	130409699 130413095(ghsrb) 130417860(ghsra)

MANU:

129425391(ghsrb) 129430424 129442238(ghsra)

IPU:	100335022 100335024(ghsrb) 108275694

IFU:	128599525(ghsrb) 128619056 128621256(ghsra)

PHYP:

113524393(ghsr) 113525610

SMEO:

124394405(ghsra) 124398850 124403789(ghsrb)

TFD:	113638098(ghsra) 113646102 113660359(ghsrb)

TVC:	132840272(ghsrb) 132858104(ghsra) 132862326

AMEX:

103029199(ghsr) 103034504 103043916

CMAO:

118797182 118798916 118822239

EEE:	113568394 113576120 113576492

CHAR:

105891412 105894704 105908527(ghsra)

TRU:	101066697(ghsr)

TFS:	130540278(ghsra)

TNG:	GSTEN00012720G001

LCO:	104920044(ghsr)

NCC:

104942334

TBEN:

117493860(ghsra)

CGOB:

115027907

PGEO:

117467900(ghsra)

GACU:

117554380 117558836(ghsra)

EMAC:

134881617(ghsra)

ELY:	117248665(ghsra)

EFO:	125901459(ghsra)

PLEP:

121953947(ghsra)

SLUC:

116057716(ghsra)

ECRA:

117936236(ghsra)

ESP:

116670608

PFLV:

114547201(ghsr)

GAT:	120833431(ghsra)

PPUG:

119228190(ghsra)

AFB:	129103738(ghsra)

CLUM:

117751122(ghsra)

PSWI:

130201060(ghsra)

MSAM:

119910946(ghsra)

SCHU:

122862129(ghsra)

CUD:	121526536(ghsra)

ALAT:

119034290(ghsra)

MZE:	101480140(ghsr)

ONL:

100699280

OAU:	116318182(ghsra)

OLA:

101167158

OML:	112143358(ghsra)

CSAI:

133462268(ghsra)

XMA:	102220554(ghsr)

XCO:

114133908

XHE:	116708665(ghsr)

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122846608(ghsra)

PPRL:

129365339(ghsra)

CVG:	107085115(ghsr)

CTUL:

119788174(ghsra)

GMU:	124855108(ghsra)

NFU:	107392073(ghsr)

KMR:	108249780(ghsra)

ALIM:

106525547(ghsr)

NWH:	119427440(ghsra)

AOCE:

111569997

MCEP:

125023679(ghsra)

CSEM:

103378932 103393713

POV:	109640855(ghsr)

SSEN:

122782618(ghsra)

HHIP:

117756512(ghsra) 117766111 117766114 117766367 117775652

HSP:	118116495(ghsra) 118119233

SMAU:

118285965(ghsra)

LCF:

108874990

SDU:

111225895

SLAL:

111665848

XGL:	120795612(ghsra)

HCQ:	109517221(ghsr)

SSCV:

125981047

SBIA:

133513263(ghsra)

PEE:	133413161(ghsra)

PTAO:

133487537(ghsra)

BPEC:

110158781(ghsr) 110171296

MALB:

109967530 109969604

BSPL:

114848973(ghsra)

SJO:	128374841(ghsra)

SASA:

100379640(ghsr) 106575425 106594151

STRU:

115176432 115179376 115182341 115195229

OTW:	112238997 112267525(ghsra) 121841112 121846184

OMY:	100136603(ghs-r) 110495701 110520795 110534239

OGO:	124006471 124008404 124011171

ONE:	115122365 115122940 115124255 115129821

OKI:	109884648 109885909 109887932 109906862

OKE:	118377689 118378328 118380335 127928118

SALP:

112074963 112075144

SNH:	120033699 120033700 120037153 120047739

CCLU:

121542724 121543188 121587432(ghsra)

ELS:	105019793 105024489

SFM:	108922888 108925309 108934981(ghsr)

PKI:	111834970 111846370 111850475 111853458(ghsr)

AANG:

118224342 118226298 118229904(ghsra)

LOC:	102691610 102695220(ghsr)

PSPA:

121305646 121323528 121327356(ghsra)

ARUT:

117404500 117416961 117423253 117967942

PSEX:

120518578(ghsra) 120526484 120538186

LCM:	102346476(GHSR) 102356891

CMK:	103190460 103190578

RTP:	109938452(ghsra)

CPLA:

122556338(ghsra)

HOC:	132821472(ghsra)

LERI:

129703413

PMRN:

116952618 116954588 116956262

LRJ:	133353809 133357206 133357411

BFO:	118413719 118414702 118428071 118428118

BBEL:

109477714 109477819 109484979

CIN:	100181208 101242126 113475788

SCLV:

120328805 120329818 120332611 120332863 120332938 120333215 120333253 120342527 120343111 120343425 120344557 120344953 120347179

LPIC:

SKO:

DER:

DMN:

DNV:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:	105180702 105185644

DQU:

106749226

CFO:	105253038 105258745

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

TPRE:

MDL:

CGLO:

CCRN:

API:

DNX:

RMD:

ACOO:

DVT:

DCI:	103516662 103519157

CLEC:

106662489

HVI:

124363059

MQU:

128988908

DPX:	DAPPUDRAFT_95505

EAF:

TCF:

LPOL:

PMEO:

LGI:	LOTGIDRAFT_135960

PVUL:

126808723 126818814 126822045 126822240

PCAN:

112553964 112561594 112570297 112570300

GAE:	121369841 121379093 121379152 121387249

HRF:	124113784 124131534 124146683

HRJ:	124256268 124256269 124259324 124282399

CRG:	105333193 105334555 105337119 105341458 105341606 105341607 109620553 117689138

CVN:	111110627 111115024 111115492 111116592 111126683 111129401 111129610 111130804 111133718

CANU:

128163990 128164007 128173103 128175821 128176484 128177063 128177463 128178703 128179039 128179072 128191136

OED:	125647313 125647314 125647460 125649373 125650451 125652044 125665704 125681418

MYI:

110445659

PMAX:

117322080 117329703 117333841 117334938 117341340

MMER:

123527671 123534892 123539202 123565490

RPHI:

132712931 132714729 132714731 132719265 132729506 132730822 132736330 132737540 132741721 132745772 132747415 132748926 132752890

DPOL:

127863735 127866593 127866594 127870056 127870413 127872184 127878811

OBI:

106873507

OSN:	115209834 115214476

LAK:

106155388

ATEN:

116286702 116289827 116292607 116292979 116298286 116300548 116300552 116306035 116306421 116308574

ADF:

107353380

PDAM:

113666629 113683964 113685193

HSY:	130624300 130655097

» show all

Reference

PMID:8688086

Authors

Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, Hamelin M, Hreniuk DL, Palyha OC, Anderson J, Paress PS, Diaz C, Chou M, Liu KK, McKee KK, Pong SS, Chaung LY, Elbrecht A, Dashkevicz M, Heavens R, Rigby M, Sirinathsinghji DJ, Dean DC, Melillo DG, Patchett AA, Nargund R, Griffin PR, DeMartino JA, Gupta SK, Schaeffer JM, Smith RG, Van der Ploeg LH

Title

A receptor in pituitary and hypothalamus that functions in growth hormone release.

Journal

Science 273:974-7 (1996)
DOI:10.1126/science.273.5277.974

Sequence

[hsa:2693]

LinkDB

DBGET integrated database retrieval system