KEGG ORTHOLOGY: K04403

ORTHOLOGY: K04403

Entry

K04403                      KO

Symbol

MAP3K7IP1, TAB1

Name

TAK1-binding protein 1

Pathway

map04010

MAPK signaling pathway

map04064

NF-kappa B signaling pathway

map04380

Osteoclast differentiation

map04620

Toll-like receptor signaling pathway

map04621

NOD-like receptor signaling pathway

map04668

TNF signaling pathway

map04936

Alcoholic liver disease

map05130

Pathogenic Escherichia coli infection

map05131

Shigellosis

map05132

Salmonella infection

map05135

Yersinia infection

map05140

Leishmaniasis

map05145

Toxoplasmosis

map05161

Hepatitis B

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05170

Human immunodeficiency virus 1 infection

map05417

Lipid and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   04064 NF-kappa B signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   04668 TNF signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   04621 NOD-like receptor signaling pathway
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05161 Hepatitis B
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05168 Herpes simplex virus 1 infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05169 Epstein-Barr virus infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05132 Salmonella infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05131 Shigellosis
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05135 Yersinia infection
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
   05140 Leishmaniasis
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1

Genes

HSA:	10454(TAB1)

PTR:	458845(TAB1)

PPS:	100985128(TAB1)

GGO:	101138846(TAB1)

PON:	103888975(TAB1)

NLE:	100587157(TAB1)

HMH:	116458812(TAB1)

MCC:	703409(TAB1)

MCF:	102122493(TAB1)

MTHB:

126963720

MNI:	105464421(TAB1)

CSAB:

103223342(TAB1)

CATY:

105572923(TAB1)

PANU:

101011339(TAB1)

TGE:	112633811(TAB1)

MLEU:

105538854(TAB1)

RRO:	104682560(TAB1)

RBB:	108520466(TAB1)

TFN:	117096466(TAB1)

PTEH:

111548993(TAB1)

CANG:

105527764(TAB1)

CJC:	100398947(TAB1)

SBQ:	101041553(TAB1)

CIMI:

108315297(TAB1)

MMUR:

105858508(TAB1)

LCAT:

123640344(TAB1)

PCOQ:

105805175(TAB1)

OGA:	100949838(TAB1)

MMU:	66513(Tab1)

MCAL:

110310212(Tab1)

MPAH:

110334874(Tab1)

RNO:	315139(Tab1)

MCOC:

116076094(Tab1)

ANU:	117719404(Tab1)

MUN:	110557813(Tab1)

CGE:	100771613(Tab1)

MAUA:

101832517(Tab1)

PROB:

127225789(Tab1)

PLEU:

114694280(Tab1)

MORG:

121461507(Tab1)

MFOT:

126515732

AAMP:

119822536(Tab1)

NGI:	103748567(Tab1)

HGL:	101696480(Tab1)

CPOC:

100735373(Tab1)

CCAN:

109692995(Tab1)

DORD:

105991989(Tab1)

DSP:	122123572(Tab1)

PLOP:

125358195(Tab1)

NCAR:

124983359

MMMA:

107155868(Tab1)

OCU:

100358246

OPI:	101519619(TAB1)

TUP:	102479566(TAB1)

GVR:	103599298(TAB1)

CFA:	481245(TAB1)

CLUD:

112667628(TAB1)

VVP:	112933980(TAB1)

VLG:	121490803(TAB1)

NPO:	129511324(TAB1)

AML:	100484077(TAB1)

UMR:	103676518(TAB1)

UAH:	113241761(TAB1)

UAR:	123780921(TAB1)

ELK:

111157505

LLV:

125106336

MPUF:

101678308(TAB1)

MNP:	132019209(TAB1)

MLK:	131839494(TAB1)

NVS:	122891933(TAB1)

ORO:	101369401(TAB1)

EJU:	114218356(TAB1)

ZCA:	113921522(TAB1)

MLX:	117998660(TAB1)

NSU:	110577941(TAB1)

LWW:	102750010(TAB1)

FCA:	101083606(TAB1)

PYU:	121040322(TAB1)

PCOO:

112863443(TAB1)

PBG:	122472775(TAB1)

PVIV:

125169755(TAB1)

LRUF:

124501060

PTG:	102950874(TAB1)

PPAD:

109265583(TAB1)

PUC:

125919627

AJU:

106981055

HHV:	120233644(TAB1)

BTA:	519958(TAB1)

BOM:	102266863(TAB1)

BIU:	109559827(TAB1)

BBUB:

102395598(TAB1)

BBIS:

104992373(TAB1)

CHX:	102185161(TAB1)

OAS:	101122943(TAB1)

BTAX:

128049014(TAB1)

ODA:	120857622(TAB1)

CCAD:

122423255(TAB1)

MBEZ:

129535825(TAB1)

SSC:	100153785(TAB1)

CFR:	102508813(TAB1)

CBAI:

105073104(TAB1)

CDK:	105091931(TAB1)

VPC:	102530894(TAB1)

BACU:

103016005(TAB1)

BMUS:

118901691(TAB1)

LVE:	103084128(TAB1)

OOR:	101282675(TAB1)

DLE:	111186464(TAB1)

PCAD:

102983590(TAB1)

PSIU:

116760244(TAB1)

NASI:

112410769(TAB1)

ECB:	100070300(TAB1)

EPZ:	103542619(TAB1)

EAI:	106836857(TAB1)

MYB:	102239405(TAB1)

MYD:	102752149(TAB1)

MMYO:

118650066(TAB1)

MLF:	102427825(TAB1)

PKL:	118728922(TAB1)

EFUS:

103288851(TAB1)

MNA:	107531263(TAB1)

DRO:	112322023(TAB1)

SHON:

119002380(TAB1)

AJM:	119060232(TAB1)

PDIC:

114513395(TAB1)

PHAS:

123816012(TAB1)

MMF:	118623445(TAB1)

PPAM:

129077831(TAB1)

HAI:	109392251(TAB1)

RFQ:	117029047(TAB1)

PALE:

102882572(TAB1)

PGIG:

120603000(TAB1)

PVP:	105298074(TAB1)

RAY:	107500809(TAB1)

MJV:

108397364

TOD:

119247246

SARA:

101547502(TAB1)

SETR:

126006234(TAB1)

LAV:	100660911(TAB1)

TMU:

101344618

ETF:	101649684(TAB1)

DNM:	101412966(TAB1)

MDO:	100012432(TAB1)

GAS:	123249564(TAB1)

SHR:	100917609(TAB1)

AFZ:

127538308

PCW:	110205796(TAB1)

OAA:	100091969(TAB1)

GGA:	418014(TAB1)

PCOC:

116233362(TAB1)

MGP:	100543083(TAB1)

CJO:	107312690(TAB1)

TPAI:

128073584(TAB1)

LMUT:

125698389(TAB1)

NMEL:

110392579(TAB1)

APLA:

101793675(TAB1)

ACYG:

106035856(TAB1)

CATA:

118250627(TAB1)

AFUL:

116486860(TAB1)

TGU:	100223478(TAB1)

LSR:	110483855(TAB1)

SCAN:

103813611(TAB1)

PMOA:

120510101(TAB1)

OTC:	121342470(TAB1)

PRUF:

121361228(TAB1)

GFR:	102037151(TAB1)

FAB:	101806997(TAB1)

OMA:	130263507(TAB1)

PHI:	102100012(TAB1)

PMAJ:

107204714(TAB1)

CCAE:

111934894(TAB1)

CCW:	104696529(TAB1)

CBRC:

103618098(TAB1)

ETL:	114055360(TAB1)

ZAB:	102067079(TAB1)

ACHL:

103801279(TAB1)

SVG:	106858544(TAB1)

MMEA:

130587694(TAB1)

HRT:	120752343(TAB1)

FPG:	101921035(TAB1)

FCH:	102056178(TAB1)

CLV:	102097298(TAB1)

EGZ:	104134239(TAB1)

NNI:	104021621(TAB1)

PCRI:

104024811(TAB1)

PLET:

104623194(TAB1)

EHS:	104511180(TAB1)

PCAO:

104048535(TAB1)

ACUN:

113487745(TAB1)

TALA:

104359596(TAB1)

PADL:

103915676(TAB1)

AFOR:

103907874(TAB1)

ACHC:

115352340(TAB1)

HALD:

104311261(TAB1)

HLE:	104830655(TAB1)

AGEN:

126047737

GCL:

127029449

CCRI:

104158154(TAB1)

CSTI:

104550541(TAB1)

CMAC:

104478097(TAB1)

MUI:	104541594(TAB1)

BREG:

104632639(TAB1)

FGA:	104075678(TAB1)

GSTE:

104261669(TAB1)

LDI:	104349085(TAB1)

MNB:	103779675(TAB1)

OHA:	104329864(TAB1)

NNT:	104400334(TAB1)

SHAB:

115605620(TAB1)

DPUB:

104302014(TAB1)

PGUU:

104467799(TAB1)

ACAR:

104518470(TAB1)

CPEA:

104394925(TAB1)

AVIT:

104275827(TAB1)

CVF:	104288376(TAB1)

RTD:	128917204(TAB1)

CUCA:

104065926(TAB1)

TEO:	104373070(TAB1)

BRHI:

104493970(TAB1)

AAM:	106488645(TAB1)

AROW:

112965723

NPD:	112947715(TAB1)

TGT:	104572947(TAB1)

DNE:	112984180(TAB1)

SCAM:

104137958(TAB1)

ASN:	102378385(TAB1)

AMJ:	102563482(TAB1)

CPOO:

109316692(TAB1)

GGN:	109295987(TAB1)

PSS:	102453103(TAB1)

CMY:	102930031(TAB1)

CCAY:

125629155(TAB1)

DCC:	119859541(TAB1)

CPIC:

101951442(TAB1)

TST:

117880237

CABI:

116824549(TAB1)

MRV:	120372053(TAB1)

ACS:	100555014(tab1)

ASAO:

132775956(TAB1)

PVT:	110088081(TAB1)

SUND:

121930589(TAB1)

PBI:	103054695(TAB1)

PMUR:

107288135

CTIG:

120304658(TAB1)

TSR:	106551715(TAB1)

PGUT:

117655410(TAB1)

APRI:

131202222(TAB1)

PTEX:

113433754(TAB1)

NSS:	113432712(TAB1)

VKO:	123035987(TAB1)

PMUA:

114605668(TAB1)

PRAF:

128421845(TAB1)

ZVI:	118090907(TAB1)

HCG:	128326448(TAB1) 128347758

GJA:	107117159(TAB1)

STOW:

125435645(TAB1)

EMC:	129336319(TAB1)

XLA:	108715765(tab1.S) 398025(tab1.L)

XTR:	549217(tab1)

NPR:	108798164(TAB1)

RTEM:

120945377(TAB1)

BBUF:

120978788(TAB1)

BGAR:

122943908(TAB1)

MUO:	115473466(TAB1)

GSH:	117353508(TAB1)

DRE:	403084(tab1)

SRX:	107737983(tab1)

SANH:

107666659(tab1)

SGH:	107555091(tab1)

CCAR:

109070198 109083633

CAUA:

113089857 113095144

CGIB:

127959411 128015300

PTET:

122333337(tab1)

LROH:

127167459(tab1)

OMC:	131541848(tab1)

PPRM:

120467961(tab1)

MAMB:

125274426(tab1)

CIDE:

127513828

MASI:

127446200 127449622

TROS:

130550475(tab1)

TDW:	130425308(tab1)

MANU:

129450667(tab1)

IPU:

108273215

IFU:	128615889(tab1)

PHYP:

113538469(tab1)

SMEO:

124386302(tab1)

TFD:	113634553(tab1)

TVC:	132844901(tab1)

AMEX:

103038577(tab1)

CMAO:

118807882(tab1)

EEE:	113579727(tab1)

CHAR:

105893549(tab1)

TRU:	101062734(tab1)

TFS:	130527758(tab1)

TNG:	GSTEN00034825G001

LCO:	104925439(tab1)

TBEN:

117496540(tab1)

CGOB:

115005482(tab1)

PGEO:

117440997(tab1)

GACU:

117555242(tab1)

EMAC:

134862741(tab1)

ELY:	117255916(tab1)

EFO:	125885436(tab1)

PLEP:

121942549(tab1)

SLUC:

116042689(tab1)

ECRA:

117952378(tab1)

ESP:	116700613(tab1)

PFLV:

114568112(tab1)

PPUG:

119217964(tab1)

AFB:	129095614(tab1)

CLUM:

117730776(tab1)

PSWI:

130190177(tab1)

MSAM:

119898614(tab1)

SCHU:

122871523(tab1)

CUD:	121509064(tab1)

ALAT:

119020932(tab1)

MZE:	101484781(tab1)

ONL:	100709656(tab1)

OAU:	116329131(tab1)

OLA:	101163057(tab1)

OML:	112137107(tab1)

CSAI:

133442583(tab1)

XMA:	102220462(tab1)

XCO:	114144243(tab1)

XHE:	116720597(tab1)

PRET:

103478828(tab1)

PFOR:

103156067(tab1)

PLAI:

106953413(tab1)

PMEI:

106923896(tab1)

GAF:	122830327(tab1)

CVG:	107084249(tab1)

CTUL:

119798256(tab1)

GMU:	124869146(tab1)

NFU:	107375154(tab1)

KMR:	108232138(tab1)

ALIM:

106522488

NWH:	119422425(tab1)

AOCE:

111577584(syngr1)

MCEP:

125003854(tab1)

CSEM:

103383419(tab1)

POV:	109639281(tab1)

SSEN:

122771099(tab1)

HHIP:

117759376(tab1)

HSP:	118124569(tab1)

SMAU:

118312566(tab1)

LCF:

108889064

SDU:	111235905(tab1)

SLAL:

111671826(tab1)

XGL:	120800783(tab1)

HCQ:	109511279(tab1)

SSCV:

125968686

SBIA:

133505815(tab1)

PEE:	133403519(tab1)

PTAO:

133476686(tab1)

BPEC:

110157716(tab1)

MALB:

109975048(tab1)

BSPL:

114859929(tab1)

SJO:	128374267(tab1)

SASA:

106590780 106594427

STRU:

115147443 115178837

OTW:	112241134 121843572

OMY:	110485597 110494935

OGO:	124003947 124004368

OKI:	109884754 109885531

OKE:	118381064(tab1)

SALP:

112072398(tab1)

SNH:

120032447

CCLU:

121555890(tab1)

ELS:	105031193(tab1)

SFM:	108928827(tab1)

PKI:	111835987(tab1)

AANG:

118216816(tab1)

PSPA:

121306093(tab1)

PSEX:

120536791(tab1)

LCM:	102359833(TAB1)

CMK:	103172117(tab1)

CPLA:

122542035(tab1)

HOC:	132831144(tab1)

LERI:

129713740(tab1)

PMRN:

116956425(TAB1)

LRJ:	133348002(TAB1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

SKO:

ECOE:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:	110681096 5565238

AALB:

109402363 109416952 115259487

CQU:	CpipJ_CPIJ001668

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

100529234(tab1)

BMAN:

114241486

MSEX:

115447620

DPL:	KGM_201704

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:	114359116 114359118

PXY:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM433350

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_300758

DMK:

116917939

DPZ:

124327152

PVM:	113803511 113817175

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

119111042 119111417 119113110

DSV:

RSAN:

RMP:

VDE:

VJA:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:	129215997 129216497

SDM:

118189513

LPOL:

106469452

PMEO:

129601603

CEL:	CELE_C44H4.5(tap-1)

CBR:	CBG_07558(Cbr-tap-1)

CRQ:	GCK72_025668

NAI:	NECAME_10649

HRO:	HELRODRAFT_171540

LGI:	LOTGIDRAFT_186175

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_21120

AQU:	100636410 100636535 100641832

BBIG:

BBBOND_0106160

» show all

Reference

PMID:8638164

Authors

Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, Matsumoto K

Title

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction.

Journal

Science 272:1179-82 (1996)
DOI:10.1126/science.272.5265.1179

Sequence

[hsa:10454]

LinkDB

DBGET integrated database retrieval system